Interaction of TWEAK with Fn14 leads to the progression of fibrotic liver disease by directly modulating hepatic stellate cell proliferation‡

Autor: Wilhelm, Annika, Shepherd, Emma L, Amatucci, Aldo, Munir, Mamoona, Reynolds, Gary, Humphreys, Elizabeth, Resheq, Yazid, Adams, David H, Hübscher, Stefan, Burkly, Linda C, Weston, Christopher J, Afford, Simon C

Publikováno v: The Journal of Pathology

Tumour necrosis factor‐like weak inducer of apoptosis (TWEAK) and its receptor fibroblast growth factor‐inducible 14 (Fn14) have been associated with liver regeneration in vivo. To further investigate the role of this pathway we examined their ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8fa6e10407fbcca8b3e30b0cae491d8b
http://europepmc.org/articles/PMC4949530

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

CD248/endosialin critically regulates hepatic stellate cell proliferation during chronic liver injury via a PDGF-regulated mechanism

Autor: Wilhelm, Annika, Aldridge, Victoria, Haldar, Debashis, Naylor, Amy J, Weston, Christopher J, Hedegaard, Ditte, Garg, Abhilok, Fear, Janine, Reynolds, Gary M, Croft, Adam P, Henderson, Neil C, Buckley, Christopher D, Newsome, Philip N

Publikováno v: Wilhelm, A, Aldridge, V, Haldar, D, Naylor, A J, Weston, C J, Hedegaard, D, Garg, A, Fear, J, Reynolds, G M, Croft, A P, Henderson, N C, Buckley, C D & Newsome, P N 2016, ' CD248/endosialin critically regulates hepatic stellate cell proliferation during chronic liver injury via a PDGF-regulated mechanism ', Gut, vol. 65, no. 7, pp. 1175-1185 . https://doi.org/10.1136/gutjnl-2014-308325
Gut

INTRODUCTION: CD248 (endosialin) is a stromal cell marker expressed on fibroblasts and pericytes. During liver injury, myofibroblasts are the main source of fibrotic matrix.OBJECTIVE: To determine the role of CD248 in the development of liver fibrosi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::43f0eda820b8e4690629109bf648fc93
https://hdl.handle.net/20.500.11820/4cfe8cd0-11a0-4826-b476-484cca404787

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.