Zobrazeno 1 - 10
of 270
pro vyhledávání: '"Wilfried Weber"'
Autor:
Pamela E. Molinari, Adriana R. Krapp, Andrea Weiner, Hannes M. Beyer, Arun Kumar Kondadi, Tim Blomeier, Melina López, Pilar Bustos-Sanmamed, Evelyn Tevere, Wilfried Weber, Andreas S. Reichert, Nora B. Calcaterra, Mathias Beller, Nestor Carrillo, Matias D. Zurbriggen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract NADP(H) is a central metabolic hub providing reducing equivalents to multiple biosynthetic, regulatory and antioxidative pathways in all living organisms. While biosensors are available to determine NADP+ or NADPH levels in vivo, no probe ex
Externí odkaz:
https://doaj.org/article/b1ef3a8f51134470b32d0beb2347929b
Autor:
Chao Su, Marta Rodriguez-Franco, Beatrice Lace, Nils Nebel, Casandra Hernandez-Reyes, Pengbo Liang, Eija Schulze, Evgeny V. Mymrikov, Nikolas M. Gross, Julian Knerr, Hong Wang, Lina Siukstaite, Jean Keller, Cyril Libourel, Alexandra A. M. Fischer, Katharina E. Gabor, Eric Mark, Claudia Popp, Carola Hunte, Wilfried Weber, Petra Wendler, Thomas Stanislas, Pierre-Marc Delaux, Oliver Einsle, Robert Grosse, Winfried Römer, Thomas Ott
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
In plants, plasma membrane topologies are predominantly driven by the cell wall. In this study, the authors demonstrate that remorin proteins can take over these functions at specialized, unwalled plasma membranes such as infection droplets associate
Externí odkaz:
https://doaj.org/article/c0bfb6f46faf4340a3db7b4eb63fdce2
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Signal processing for downstream functional and morphological adaptations is crucial for understanding and re-enacting features of living systems. Here, the authors show DNAzyme-containing, metabolic protocells that induce prototissue formation via c
Externí odkaz:
https://doaj.org/article/06678f59ad9d42b380bcb8a872eb566a
Autor:
Marissa Russ, Anna K. Ehret, Maximilian Hörner, Daniel Peschkov, Rebecca Bohnert, Vincent Idstein, Susana Minguet, Wilfried Weber, Björn F. Lillemeier, O. Sascha Yousefi, Wolfgang W. Schamel
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
The kinetics of a ligand-receptor interaction determine the responses of the receptor-expressing cell. One approach to experimentally and reversibly change this kinetics on demand is optogenetics. We have previously developed a system in which the in
Externí odkaz:
https://doaj.org/article/ceac173bb5db4dc798bfa3529829a5dc
Publikováno v:
Advanced Science, Vol 8, Iss 9, Pp n/a-n/a (2021)
Abstract Three recent approvals and over 100 ongoing clinical trials make adeno‐associated virus (AAV)‐based vectors the leading gene delivery vehicles in gene therapy. Pharmaceutical companies are investing in this small and nonpathogenic gene s
Externí odkaz:
https://doaj.org/article/3e9715ac034b476fb1e20d318f83b8c4
Autor:
Philipp S. Lienemann, Queralt Vallmajo‐Martin, Panagiota Papageorgiou, Ulrich Blache, Stéphanie Metzger, Anna‐Sofia Kiveliö, Vincent Milleret, Ana Sala, Sylke Hoehnel, Aline Roch, Raphael Reuten, Manuel Koch, Olaia Naveiras, Franz E. Weber, Wilfried Weber, Matthias P. Lutolf, Martin Ehrbar
Publikováno v:
Advanced Science, Vol 7, Iss 7, Pp n/a-n/a (2020)
Abstract The treatment of bone defects with recombinant bone morphogenetic protein‐2 (BMP‐2) requires high doses precluding broad clinical application. Here, a bioengineering approach is presented that strongly improves low‐dose BMP‐2‐based
Externí odkaz:
https://doaj.org/article/ff1b5c7bb89f4cc493ad1ee1b1a8a396
Autor:
O. Sascha Yousefi, Maximilian Hörner, Maximilian Wess, Vincent Idstein, Wilfried Weber, Wolfgang Schamel
Publikováno v:
Bio-Protocol, Vol 10, Iss 5 (2020)
T cells are one major cell type of the immune system that use their T cell antigen receptor (TCR) to bind and respond to foreign molecules derived from pathogens. The ligand-TCR interaction half-lives determine stimulation outcome. Until recently, sc
Externí odkaz:
https://doaj.org/article/570978d322d0438cac185007171e3556
Publikováno v:
Bio-Protocol, Vol 10, Iss 5 (2020)
In the field of extracellular optogenetics, photoreceptors are applied outside of cells to obtain systems with a desired functionality. Among the diverse applied photoreceptors, phytochromes are the only ones that can be actively and reversibly switc
Externí odkaz:
https://doaj.org/article/9384861756e04d268228f37099a8b27b
Autor:
Ramona Emig, Callum M. Zgierski-Johnston, Friedhelm Beyersdorf, Bartosz Rylski, Ursula Ravens, Wilfried Weber, Peter Kohl, Maximilian Hörner, Rémi Peyronnet
Publikováno v:
Frontiers in Physiology, Vol 10 (2020)
Fibrosis is associated with aging and many cardiac pathologies. It is characterized both by myofibroblast differentiation and by excessive accumulation of extracellular matrix proteins. Fibrosis-related tissue remodeling results in significant change
Externí odkaz:
https://doaj.org/article/c7d0df74de5f42d3a032870173bb4551
Autor:
Oliver S. Thomas, Wilfried Weber
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 7 (2019)
The exploitation of nanosized materials for the delivery of therapeutic agents is already a clinical reality and still holds unrealized potential for the treatment of a variety of diseases. This review discusses physiological barriers a nanocarrier m
Externí odkaz:
https://doaj.org/article/bebe0730c2374990a3f064e319730048