Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Wilfried Kramer"'
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0136778 (2015)
A major challenge in gene library generation is to guarantee a large functional size and diversity that significantly increases the chances of selecting different functional protein variants. The use of trinucleotides mixtures for controlled randomiz
Externí odkaz:
https://doaj.org/article/ea1b5bd7f9d34ea8a9695dc30acf0537
Publikováno v:
Yeast. 34:459-470
Gle2/Rae1 is highly conserved from yeast to humans and has been described as an mRNA export factor. Additionally, it is implicated in the anaphase-promoting complex-mediated cell cycle regulation in higher eukaryotes. Here we identify an involvement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::621e9546e6bca5511cdf811b5e0da287
https://doi.org/10.1002/yea.3249
https://doi.org/10.1002/yea.3249
Publikováno v:
DNA Repair. 10:45-55
Stalling of replication forks at lesions is a serious threat to genomic integrity and cell viability. Cells have developed a variety of pathways that allow continuation of synthesis, including translesion synthesis, postreplication repair and homolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18c2ec5a625bbc3cdb6177acdb6d32df
https://doi.org/10.1016/j.dnarep.2010.09.009
https://doi.org/10.1016/j.dnarep.2010.09.009
Autor:
Sabine Smolorz, Svetlana Ber, Elena Ciirdaeva, Wilfried Kramer, Hans-Joachim Fritz, Lars Schomacher
Publikováno v:
Nucleic Acids Research
The mutagenic threat of hydrolytic DNA cytosine deamination is met mostly by uracil DNA glycosylases (UDG) initiating base excision repair. However, several sequenced genomes of archaeal organisms are devoid of genes coding for homologues of the othe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::830372f26fd38ca88d1b1e57e9363f81
https://doi.org/10.1093/nar/gkq270
https://doi.org/10.1093/nar/gkq270
Autor:
Lars Schomacher, Hans-Joachim Fritz, Elena Ciirdaeva, K. Anke Schürer, Paul McDermott, Wilfried Kramer, James P. J. Chong
Publikováno v:
DNA Repair. 9:438-447
Hydrolytic deamination of DNA cytosine residues results in U/G mispairs, pre-mutagenic lesions threatening long-term genetic stability. Hence, DNA uracil repair is ubiquitous throughout all extant life forms and base excision repair, triggered by a u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::527cfd7832f830c4b9405ec3b2591f17
https://doi.org/10.1016/j.dnarep.2010.01.004
https://doi.org/10.1016/j.dnarep.2010.01.004
Autor:
Evandro Rocco Panico, Christopher Ede, Michael Schildmann, Kirsten Anke Schürer, Wilfried Kramer
Publikováno v:
Yeast. 27:11-27
In yeast as in human, DNA helicases play critical roles in assisting replication fork progression. The Saccharomyces cerevisiae MPH1 gene, homologue of human FANCM, has been involved in homologous recombination and DNA repair. We describe a synthetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9b1caf9d3f2b3051378ed7e68fc6162
https://doi.org/10.1002/yea.1727
https://doi.org/10.1002/yea.1727
Publikováno v:
Nucleic Acids Research
No genes for any of the known uracil DNA glycosylases of the UDG superfamily are present in the genome of Methanothermobacter thermautotrophicus DeltaH, making it difficult to imagine how DNA-U repair might be initiated in this organism. Recently, Mt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec7464eaad0da14ce8313def491c7a8f
http://europepmc.org/articles/PMC2673441
http://europepmc.org/articles/PMC2673441
Publikováno v:
Medizinische Klinik. 104:52-57
Ein 59-jahriger Mann wurde zur Abklarung einer seit 4 Wochen bestehenden Symptomatik aus Luftnot, Husten und thorakalem Engegefuhl stationar eingewiesen. Zudem berichtete er uber erhohte Temperaturen und Abgeschlagenheit. Kardiovaskulare Risikofaktor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ad8734543ac81b396d3939cc24d1e5e
https://doi.org/10.1007/s00063-009-1006-x
https://doi.org/10.1007/s00063-009-1006-x
Publikováno v:
Medizinische Klinik. 103:827-830
The cause of severe cardiac conduction disturbances or sinus node dysfunction is often unknown. The objective of this study was to assess the incidence of coronary artery disease (CAD) and the necessity of revascularization in patients with symptomat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49c5fe3e92184714ff0536cbd7671417
https://doi.org/10.1007/s00063-008-1130-z
https://doi.org/10.1007/s00063-008-1130-z
Koinzidenz von koronarer Herzkrankheit und Takotsubo-Kardiomyopathie bei einer 72-jährigen Patientin
Publikováno v:
Medizinische Klinik. 103:665-669
Bei der Takotsubo-Kardiomyopathie handelt es sich um ein Krankheitsbild mit reversiblen Wandbewegungsstorungen des linken Ventrikels bei angiographisch unauffalligen Koronararterien. Die Koinzidenz einer koronaren Herzkrankheit und einer Takotsubo-Ka
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b58b960fe434ee0b427445a5bda2730
https://doi.org/10.1007/s00063-008-1105-0
https://doi.org/10.1007/s00063-008-1105-0