Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Wilfredo F. García-Beltrán"'
Autor:
David J. Gregory, Augustin Vannier, Akiro H. Duey, Tyler J. Roady, Richard K. Dzeng, Maia N. Pavlovic, Michael H. Chapin, Sonia Mukherjee, Hannah Wilmot, Nic Chronos, Richelle C. Charles, Edward T. Ryan, Regina C. LaRocque, Tyler E. Miller, Wilfredo F. Garcia-Beltran, Julia C. Thierauf, A. John Iafrate, Steven Mullenbrock, Mark D. Stump, Randall K. Wetzel, Roberto D. Polakiewicz, Vivek Naranbhai, Mark C. Poznansky
Publikováno v:
Virulence, Vol 13, Iss 1, Pp 890-902 (2022)
Antibodies to SARS-CoV-2 are central to recovery and immunity from COVID-19. However, the relationship between disease severity and the repertoire of antibodies against specific SARS-CoV-2 epitopes an individual develops following exposure remains in
Externí odkaz:
https://doaj.org/article/e0d631b0eef044d7b1cd22855041802d
Autor:
José A. Lasalde-Dominicci, Coral M. Capó-Vélez, Roberto I. Melendez, Edwin Vázquez-Rosa, José R. Mercado, Félix M. Ramos, Leomar Ballester, Wilfredo F. García-Beltrán, Raymond Rios
Publikováno v:
Journal of Biological Chemistry. 287:3079-3086
Approximately 30–50% of the >30 million HIV-infected subjects develop neurological complications ranging from mild symptoms to dementia. HIV does not infect neurons, and the molecular mechanisms behind HIV-associated neurocognitive decline are not
Autor:
Kim Vanuytsel, Carlos Villacorta-Martin, Jonathan Lindstrom-Vautrin, Zhe Wang, Wilfredo F. Garcia-Beltran, Vladimir Vrbanac, Dylan Parsons, Evan C. Lam, Taylor M. Matte, Todd W. Dowrey, Sara S. Kumar, Mengze Li, Feiya Wang, Anthony K. Yeung, Gustavo Mostoslavsky, Ruben Dries, Joshua D. Campbell, Anna C. Belkina, Alejandro B. Balazs, George J. Murphy
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
During human embryonic development, haematopoietic stem cells of the foetal liver undergo expansion, while retaining engraftment capacity. Here the authors apply CITE-seq to profile single cells from a human foetal liver, identifying a molecular sign
Externí odkaz:
https://doaj.org/article/cac11a57fa10405ca22f6fddb6df2365
Autor:
Klara Klein, Angelique Hölzemer, Tim Wang, Tae-Eun Kim, Haley L. Dugan, Stephanie Jost, Marcus Altfeld, Wilfredo F. Garcia-Beltran
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
While human leukocyte antigen (HLA) and HLA-like proteins comprise an overwhelming majority of known ligands for NK-cell receptors, the interactions of NK-cell receptors with non-conventional ligands, particularly carbohydrate antigens, is less well
Externí odkaz:
https://doaj.org/article/817f14afd14f4171ab4d81ffe9b0d460
Autor:
Wilfredo F. Garcia-Beltran, Daniel T. Claiborne, Colby R. Maldini, Meredith Phelps, Vladimir Vrbanac, Marshall E. Karpel, Katharine L. Krupp, Karen A. Power, Christian L. Boutwell, Alejandro B. Balazs, Andrew M. Tager, Marcus Altfeld, Todd M. Allen
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Humanized bone marrow-liver-thymus (HuBLT) mice are a revolutionary small-animal model that has facilitated the study of human immune function and human-restricted pathogens, including human immunodeficiency virus type 1 (HIV-1). These mice recapitul
Externí odkaz:
https://doaj.org/article/e6c1b3fbd7f14cf4a30a0e8d524ed2d0
Autor:
Anaïs Chapel, Wilfredo F. Garcia-Beltran, Angelique Hölzemer, Maja Ziegler, Sebastian Lunemann, Gloria Martrus, Marcus Altfeld
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract The activating NK cell receptor KIR2DS1 has been shown to be involved in many disorders including autoimmune diseases, malignancies and pregnancy outcomes. However, the precise ligands and functions of this receptor remain unclear. We aimed
Externí odkaz:
https://doaj.org/article/3a5085e41caa41e8b81a476f571ddaf4
Autor:
Maja Christiane Ziegler, Ferran Borràs Grañana, Wilfredo F. Garcia-Beltran, Julian Schulze zur Wiesch, Christian Hoffmann, Anne Rechtien, Sebastian Lunemann, Marcus Altfeld
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Inhibitory KIRs play a central role in regulating NK cell activity. KIR2DL2/3 bind to HLA-C molecules, but the modulation of these interactions by viral infections and presentation of viral epitopes is not well-understood. We investigated whether the
Externí odkaz:
https://doaj.org/article/a45c8acba21940fc982c326d263ff615
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Natural killer (NK) cells are effector lymphocytes of the innate immune system that are able to mount a multifaceted antiviral response within hours following infection. This is achieved through an array of cell surface receptors surveilling host cel
Externí odkaz:
https://doaj.org/article/a0fcd3e322e24dcdbf73a333db58d75d