Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Wilfred W. Li"'
Molecular Dynamics Analysis of Antibody Recognition and Escape by Human H1N1 Influenza Hemagglutinin
Publikováno v:
Biophysical Journal. 108:2704-2712
The antibody immunoglobulin (Ig) 2D1 is effective against the 1918 hemagglutinin (HA) and also known to cross-neutralize the 2009 pandemic H1N1 influenza HA through a similar epitope. However, the detailed mechanism of neutralization remains unclear.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea91283348bd980fed2adccf9cf7eec6
https://doi.org/10.1016/j.bpj.2015.04.025
https://doi.org/10.1016/j.bpj.2015.04.025
Publikováno v:
Concurrency and Computation: Practice and Experience. 26:878-893
The MapReduce programming model has proven useful for data-driven high throughput applications. However, the conventional MapReduce model limits itself to scheduling jobs within a single cluster. As job sizes become larger, single-cluster solutions g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::feb6827a9015f5697a545a84824d4036
https://doi.org/10.1002/cpe.2929
https://doi.org/10.1002/cpe.2929
Autor:
Jens Erik Nielsen, Samir Unni, Nathan A. Baker, Robert M. Hanson, Sriram Krishnan, Wilfred W. Li, Yong Huang, Malcolm Tobias
Publikováno v:
Journal of Computational Chemistry. 32:1488-1491
APBS and PDB2PQR are widely utilized free software packages for biomolecular electrostatics calculations. Using the Opal toolkit, we have developed a Web services framework for these software packages that enables the use of APBS and PDB2PQR by users
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f1553396c1bca009abb02ce0d4c0d13
https://doi.org/10.1002/jcc.21720
https://doi.org/10.1002/jcc.21720
Publikováno v:
Nucleic Acids Research
The proteome-wide characterization and analysis of protein ligand-binding sites and their interactions with ligands can provide pivotal information in understanding the structure, function and evolution of proteins and for designing safe and efficien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e590656cae58801799c455e05c9655ef
https://doi.org/10.1093/nar/gkq400
https://doi.org/10.1093/nar/gkq400
Autor:
William Stafford Noble, Jingyuan Ren, Luca Clementi, Fabian A. Buske, Martin C. Frith, Wilfred W. Li, Mikael Bodén, Timothy L. Bailey, Charles E. Grant
Publikováno v:
Nucleic Acids Research
The MEME Suite web server provides a unified portal for online discovery and analysis of sequence motifs representing features such as DNA binding sites and protein interaction domains. The popular MEME motif discovery algorithm is now complemented b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52f7854c3da49c2e356cb2d520af2bd3
https://doi.org/10.1093/nar/gkp335
https://doi.org/10.1093/nar/gkp335
Autor:
Anushka Michailova, Jeffrey J. Saucerman, Peter Arzberger, Shaoying Lu, Michael Holst, Andrew D. McCulloch, Masahiko Hoshijima, James Andrew McCammon, Takeharu Hayashi, Wilfred W. Li, Zeyun Yu, Yuhui Cheng, T. Kaiser, Randolph E. Bank
Publikováno v:
IEEE Engineering in Medicine and Biology Magazine. 28:46-57
This paper indicates that in ventricular myocytes when the SR (sarcoplasmic reticulum) is pharmacologically inhibited, the intracellular Ca2+concentration rapidly increases during Ca2+ entrance (0-70 ms), whereas the decay of Ca2+ is slow; in the abs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcc1a0d224e4f9c5fdee93b9a28474c2
https://doi.org/10.1109/memb.2009.931787
https://doi.org/10.1109/memb.2009.931787
Autor:
Peter Arzberger, J. Andrew McCammon, E. Irene Newhouse, Wilfred W. Li, Dong Xu, Lily S. Cheng, Hsing C. Pao, Rommie E. Amaro, Phineus R. L. Markwick
Publikováno v:
Journal of Molecular Biology. 387:465-491
Hemagglutinin (HA) binds to sialylated glycans exposed on the host cell surface in the initial stage of avian influenza virus infection. It has been previously hypothesized that glycan topology plays a critical role in the human adaptation of avian f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6abff873bd772f04224498921092c5e8
https://doi.org/10.1016/j.jmb.2009.01.040
https://doi.org/10.1016/j.jmb.2009.01.040
Publikováno v:
New Generation Computing. 25:373-394
As more and more life science researchers start to take advantages of grid technologies in their work, the demand increases for a robust yet easy to use metascheduler or resource broker. In this paper, we have extended the metascheduler CSF4 by provi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44a0e480e5c3f8c2fd62ffa397a41a06
https://doi.org/10.1007/s00354-007-0024-6
https://doi.org/10.1007/s00354-007-0024-6
Publikováno v:
Nucleic Acids Research
MEME (Multiple EM for Motif Elicitation) is one of the most widely used tools for searching for novel 'signals' in sets of biological sequences. Applications include the discovery of new transcription factor binding sites and protein domains. MEME wo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03e28d24c9e235109308f870bf988f41
https://doi.org/10.1093/nar/gkl198
https://doi.org/10.1093/nar/gkl198
Publikováno v:
Journal of the American Chemical Society
Within influenza viral particles, the intricate balance between host cell binding and sialic acid receptor destruction is carefully maintained by the hemagglutinin (HA) and neuraminidase (NA) glycoproteins, respectively. A major outstanding question
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30134c651b876cbc2363e8391bf0f2b9
https://doi.org/10.1021/ja9073672
https://doi.org/10.1021/ja9073672