Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Wilfred F. A. den Dunnen"'
Autor:
Christos E. Zois, Anne M. Hendriks, Syed Haider, Elisabete Pires, Esther Bridges, Dimitra Kalamida, Dimitrios Voukantsis, B. Christoffer Lagerholm, Rudolf S. N. Fehrmann, Wilfred F. A. den Dunnen, Andrei I. Tarasov, Otto Baba, John Morris, Francesca M. Buffa, James S. O. McCullagh, Mathilde Jalving, Adrian L. Harris
Publikováno v:
Cell Death and Disease, Vol 13, Iss 6, Pp 1-15 (2022)
Abstract Channelling of glucose via glycogen, known as the glycogen shunt, may play an important role in the metabolism of brain tumours, especially in hypoxic conditions. We aimed to dissect the role of glycogen degradation in glioblastoma (GBM) res
Externí odkaz:
https://doaj.org/article/b1ef617fb3104ffda4ec574e955e7b3f
Autor:
Bart R. J. van Dijken, Hanne-Rinck Jeltema, Justyna Kłos, Peter Jan van Laar, Roelien H. Enting, Ronald G. H. J. Maatman, Klaas Bijsterveld, Wilfred F. A. Den Dunnen, Rudi A. Dierckx, Paul E. Sijens, Anouk van der Hoorn
Publikováno v:
Diagnostics, Vol 13, Iss 17, p 2791 (2023)
Isocitrate dehydrogenase (IDH) mutation status is an important biomarker in the glioma-defining subtype and corresponding prognosis. This study proposes a straightforward method for 2-hydroxyglutarate (2-HG) quantification by MR spectroscopy for IDH
Externí odkaz:
https://doaj.org/article/88d6706036dd49d38b2cb0651fcfd264
Autor:
Marcus C. M. Stroet, Bianca M. Dijkstra, Sebastiaan E. Dulfer, Schelto Kruijff, Wilfred F. A. den Dunnen, Frank A. E. Kruyt, Rob J. M. Groen, Yann Seimbille, Kranthi M. Panth, Laura Mezzanotte, Clemens W. G. M. Lowik, Marion de Jong
Publikováno v:
EJNMMI Research, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Background There is a growing body of nuclear contrast agents that are repurposed for fluorescence-guided surgery. New contrast agents are obtained by substituting the radioactive tag with, or adding a fluorescent cyanine to the molecular st
Externí odkaz:
https://doaj.org/article/4aebdcf478de47da9c40600858fc1dba
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Externí odkaz:
https://doaj.org/article/bccf2026c4564135a2b9c700f2e4b32e
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Alzheimer’s disease (AD), the most common form of dementia, currently affects 40–50 million people worldwide. Despite the extensive research into amyloid β (Aβ) deposition and tau protein hyperphosphorylation (p-tau), an effective treatment to
Externí odkaz:
https://doaj.org/article/70e3ebdf0f3a4ca586fca500825cfac0
Autor:
Larissa E. van Eijk, Adriana Tami, Jan-Luuk Hillebrands, Wilfred F. A. den Dunnen, Martin H. de Borst, Peter H. J. van der Voort, Marian L. C. Bulthuis, Alida C. M. Veloo, Karin I. Wold, María F. Vincenti González, Bernardina T. F. van der Gun, Harry van Goor, Arno R. Bourgonje
Publikováno v:
Antioxidants, Vol 10, Iss 12, p 2022 (2021)
Oxidative stress has been implicated to play a critical role in the pathophysiology of coronavirus disease 2019 (COVID-19) and may therefore be considered as a relevant therapeutic target. Serum free thiols (R-SH, sulfhydryl groups) comprise a robust
Externí odkaz:
https://doaj.org/article/41f67a41a6a14cf7afdae82c5b5b9171
Autor:
Esteban M Rodríguez, María M Guerra, Karin Vío, César González, Alexander Ortloff, Luis F Bátiz, Sara Rodríguez, María C Jara, Rosa I Muñoz, Eduardo Ortega, Jaime Jaque, Francisco Guerra, Deborah A Sival, Wilfred F. A. den Dunnen, Antonio J Jiménez, María D Domínguez-Pinos, José M Pérez-Fígares, James P McAllister, Conrad Johanson
Publikováno v:
Biological Research, Vol 45, Iss 3, Pp 231-241 (2012)
Most cells of the developing mammalian brain derive from the ventricular (VZ) and the subventricular (SVZ) zones. The VZ is formed by the multipotent radial glia/neural stem cells (NSCs) while the SVZ harbors the rapidly proliferative neural precurso
Externí odkaz:
https://doaj.org/article/8d0adf41333a41d9958c176c1bcab3bd
Autor:
Bianca M, Dijkstra, Julie, Nonnekens, Wouter, Nagengast, Schelto, Kruijff, Gert Jan, Meersma, Wilfred F A, den Dunnen, Frank A E, Kruyt, Rob J M, Groen
Publikováno v:
Journal of Neurosurgery, 138(5), 1263-1272. American Association of Neurological Surgeons
OBJECTIVE Meningiomas are frequently occurring, often benign intracranial tumors. Molecular fluorescence can be used to intraoperatively identify residual meningioma tissue and optimize safe resection; however, currently no clinically approved agent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9e8e2781d93adb40bb6b12ca8ab056c
https://pure.eur.nl/en/publications/3d1ec1d0-8c62-4100-835a-d85849ec1dad
https://pure.eur.nl/en/publications/3d1ec1d0-8c62-4100-835a-d85849ec1dad
Autor:
Eelke M. Bos, Wilfred F. A. den Dunnen, Marcel G. M. Olde Rikkert, Annette K. Offringa, Amaal Eman Abdulle, Nikola Kolundzic, Douwe J. Mulder, Jan-Luuk Hillebrands, Harry van Goor, Johannes G. van der Hoeven, Mathijs Binkhorst, Larissa E. van Eijk, Peter H. J. van der Voort, Arno R. Bourgonje
Publikováno v:
The Journal of Pathology
Journal of Pathology, 254, 4, pp. 307-331
The journal of pathology, Early View
Journal of Pathology, 254, 307-331
Journal of Pathology, 254, 4, pp. 307-331
The journal of pathology, Early View
Journal of Pathology, 254, 307-331
Contains fulltext : 234014.pdf (Publisher’s version ) (Open Access) Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continues to spread globally despite the worldwide implementation of pr
Autor:
Marion de Jong, Yann Seimbille, Schelto Kruijff, Rob J. M. Groen, Clemens W G M Löwik, Bianca M. Dijkstra, Wilfred F. A. den Dunnen, Laura Mezzanotte, Frank A.E. Kruyt, Sebastiaan E. Dulfer, Marcus C. M. Stroet, Kranthi M. Panth
Publikováno v:
EJNMMI Research, 11(1):47, 1-8. SpringerOpen
EJNMMI research, vol. 11, no. 1, pp. 47
EJNMMI Research, 11:47. Springer-Verlag
EJNMMI Research, Vol 11, Iss 1, Pp 1-8 (2021)
EJNMMI research, vol. 11, no. 1, pp. 47
EJNMMI Research, 11:47. Springer-Verlag
EJNMMI Research, Vol 11, Iss 1, Pp 1-8 (2021)
Background There is a growing body of nuclear contrast agents that are repurposed for fluorescence-guided surgery. New contrast agents are obtained by substituting the radioactive tag with, or adding a fluorescent cyanine to the molecular structure o