Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Wilford Tse"'
Autor:
Chee Fan Tan, Hui San Teo, Jung Eun Park, Bamaprasad Dutta, Shun Wilford Tse, Melvin Khee-Shing Leow, Walter Wahli, Siu Kwan Sze
Publikováno v:
Cells, Vol 9, Iss 5, p 1320 (2020)
Studies have shown that the process of extracellular vesicles (EVs) secretion and lysosome status are linked. When the lysosome is under stress, the cells would secrete more EVs to maintain cellular homeostasis. However, the process that governs lyso
Externí odkaz:
https://doaj.org/article/59c6442a021c414f9d523c7c43b639d5
Autor:
Bamaprasad Dutta, Shun Wilford Tse, James P. Tam, Kheng Wei Yeoh, Jee Keem Low, Oi Lian Kon, Siu Kwan Sze, Jung Eun Park, Nikhil Gupta, Chee Fan Tan
Publikováno v:
Oncogene. 38:5158-5173
Developing tumors rapidly outgrow their oxygen supply and are subject to hypoxia, which stimulates hypersecretion of tumor-derived exosomes that promote angiogenesis, metastasis, and immunosuppression, but the molecular mediators of these pathologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::513c3976389d148d77a88922546c2c6c
https://doi.org/10.1038/s41388-019-0782-x
https://doi.org/10.1038/s41388-019-0782-x
Autor:
Hui Qi Vanessa Koh, Jian Qing Lin, Kevin Pethe, Huan Jia, Muhammad Taufiq Jaafa, Sylvie Alonso, Swathi Pasunooti, Sze Wai Ng, So Fong Cam Ngan, Jieling Lim, Wilford Tse, Jie Yin Grace Ngan, Wei Meng, Siu Kwan Sze, Julien Lescar, Noradibah Abdul Ghani, Su Lei Sharol Cho
Publikováno v:
Proc Natl Acad Sci U S A
GTPase high f requency of l ysogenization X (HflX) is highly conserved in prokaryotes and acts as a ribosome-splitting factor as part of the heat shock response in Escherichia coli. Here we report that HflX produced by slow-growing Mycobacterium bovi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce468437b222899a0e83f2948051b57e
https://europepmc.org/articles/PMC8000101/
https://europepmc.org/articles/PMC8000101/
Publikováno v:
Biochemical Journal
Nitrite binding to recombinant wild-type Sperm Whale myoglobin (SWMb) was studied using a combination of spectroscopic methods including room-temperature magnetic circular dichroism. These revealed that the reactive species is free nitrous acid and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::414b1bd2c047a5c14a44f78916e3a8fb
https://ueaeprints.uea.ac.uk/id/eprint/79380/
https://ueaeprints.uea.ac.uk/id/eprint/79380/
Autor:
Jee Keem Low, Chor Yong Tay, Kheng Wei Yeoh, Jung Eun Park, Shun Wilford Tse, Sai Kiang Lim, Neil E. McCarthy, JebaMercy Gnanasekaran, Wee Joo Chng, Nikhil Gupta, Siu Kwan Sze, Chee Fan Tan
Publikováno v:
Cancers
Volume 12
Issue 10
Cancers, Vol 12, Iss 2917, p 2917 (2020)
Volume 12
Issue 10
Cancers, Vol 12, Iss 2917, p 2917 (2020)
Simple Summary Human cells can communicate with each other by releasing small packets of protein called ‘vesicles’ that are absorbed by other cells nearby and at distant locations, leading to major changes in biological activity. This is also the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8653e70a2b9e87cd522ff6949abee1de
https://pubmed.ncbi.nlm.nih.gov/33050615
https://pubmed.ncbi.nlm.nih.gov/33050615
Autor:
Shun Wilford Tse, Chee Fan Tan, Jung Eun Park, JebaMercy Gnanasekaran, Nikhil Gupta, Jee Keem Low, Kheng Wei Yeoh, Wee Joo Chng, Chor Yong Tay, Neil McCarthy, Sai Kiang Lim, Siu Kwan Sze
Background: Extracellular vesicles (EVs) mediate critical intercellular communication within healthy tissues, but are also exploited by tumour cells to promote angiogenesis, metastasis, and host immunosuppression under hypoxic stress. We hypothesize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ffbed2cc8d13db5d5b7819259778066
https://doi.org/10.21203/rs.3.rs-42528/v1
https://doi.org/10.21203/rs.3.rs-42528/v1
Autor:
Koh Hqv, Ng Sw, Ngan Sfc, Cho Sls, Julien Lescar, Kevin Pethe, Abdulghani N, Huan Jia, Jun Yi Stanley Lim, Sylvie Alonso, Wilford Tse, Ngan Jyg, Jaafar Mt, Swathi Pasunooti, Wei Meng, Siu Kwan Sze
GTPase HflX is highly conserved in prokaryotes and is a ribosome splitting factor during heat shock in E. coli. Here we report that HflX produced by slow growing M. tuberculosis and M. bovis BCG is a GTPase that plays a critical role in the pathogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6462846f8b46ae2da2a4cbb858fea878
Autor:
Low Jee Kim, Wilford Tse, Neil E. McCarthy, Siu Kwan Sze, Jung Eun Park, Oi Lian Kon, Nikhil Gupta
Publikováno v:
Oncotarget
Pancreatic cancer is a leading cause of mortality worldwide due to difficulty detecting early-stage disease and our poor understanding of the mediators that drive the progression of hypoxic solid tumours. We, therefore, used a heavy isotope ‘pulse/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5809cd825aae6d4b8185f01a5be96ca8
https://pubmed.ncbi.nlm.nih.gov/31666928
https://pubmed.ncbi.nlm.nih.gov/31666928
Autor:
Oi Lian Kon, Gallart Palau Xavier Ramon, James P. Tam, Aida Serra Maqueda, Siu Kwan Sze, Guo Xue, Chor Yong Tay, Shun Wilford Tse, Christina Assisi, Jung Eun Park, Jee Keem Low
Publikováno v:
Oncotarget
Hypoxia is an environmental cue that is associated with multiple tumorigenic processes such as immunosuppression, angiogenesis, cancer invasion, metastasis, drug resistance, and poor clinical outcomes. When facing hypoxic stress, cells initiate sever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0bf3e7e89fd3af9230907990119bcae
https://hdl.handle.net/10356/145346
https://hdl.handle.net/10356/145346