Zobrazeno 1 - 10
of 265
pro vyhledávání: '"Wiley J. Youngs"'
Autor:
Kylin A. Emhoff, Lakshmi Balaraman, Sydney R. Simpson, Michael L. Stromyer, Haitham F. Kalil, James R. Beemiller, Philipp Sikatzki, Teya S. Eshelman, Ahmed M. H. Salem, Michael A. DeBord, Matthew J. Panzner, Wiley J. Youngs, W. Christopher Boyd
Publikováno v:
ACS Omega, Vol 3, Iss 11, Pp 16021-16027 (2018)
Externí odkaz:
https://doaj.org/article/fcc2ec5796664e269dc1da87392cdc7a
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 71, Iss 4, Pp 357-359 (2015)
In the title compound, C18H14O, with systematic name 1-(anthracen-9-yl)-2-methylprop-2-en-1-one, the ketonic C atom lies 0.2030 (16) Å out of the anthryl-ring-system plane. The dihedral angle between the planes of the anthryl and methacryloyl moieti
Externí odkaz:
https://doaj.org/article/e17b4c69285e435d90a59ff9aaaac210
Publikováno v:
Molecules, Vol 22, Iss 8, p 1263 (2017)
Because of their great structural diversity and multitude of chemical properties, N-heterocyclic carbenes (NHCs) have been utilized in a variety of capacities. Most recently, NHCs have been utilized as carrier molecules for many transition metals in
Externí odkaz:
https://doaj.org/article/178e6eb4f68141af9efd39906c293faf
Publikováno v:
Acta Crystallographica Section E, Vol 67, Iss 9, Pp m1178-m1179 (2011)
Ethanesulfonic acid-based buffers like 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid (HEPES) are commonly used in biological experiments because of their ability to act as non-coordinating ligands towards metal ions. However, recent work ha
Externí odkaz:
https://doaj.org/article/194c49ed931940d29f1fefce74f5b398
Publikováno v:
Acta Crystallographica Section E, Vol 65, Iss 1, Pp m105-m105 (2009)
Single crystals of the title compound bis[bis(1-ethyl-3-methyl-imidazol-2-ylidene)silver(I)] 1,5,5,7,11,11-hexachloro-2,8-dioxa-4,6,10,12,13,14-hexaaza-1λ5,3,5λ5,7λ5,9,11λ5-hexaphosphatricyclo[7.3.1.13,7]tetradeca-1(13),4,7(14),10-tetraene-6,12-d
Externí odkaz:
https://doaj.org/article/4f446997a1ec4c71852cf358ed74c513
Publikováno v:
Bladder Cancer. 6:471-479
BACKGROUND: Bladder cancer is one of the most common types of cancer diagnosed each year, and more than half of patients have non-muscle invasive bladder cancer (NMIBC). The standard of care for patients with high-grade NMIBC is Bacillus Calmette-Gue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74cb5b865e54215fc7d872ee590048d4
https://doi.org/10.3233/blc-200340
https://doi.org/10.3233/blc-200340
Autor:
Uttam Satyal, David Weader, Henkel Valentine, Michael Stromyer, Wiley J. Youngs, Philip H. Abbosh
Publikováno v:
Cancer Research. 82:4058-4058
Introduction: Intravesical therapy is critical in management of high-risk non-muscle invasive bladder cancer. The most effective intravesical therapy, BCG, has an ongoing shortage, while other second line therapies are not very effective, leaving rad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ddc435bb80d92f7d4a840c65a8a07fd
https://doi.org/10.1158/1538-7445.am2022-4058
https://doi.org/10.1158/1538-7445.am2022-4058
Autor:
Sailaja Paruchuri, Nikki K. Robishaw, Michael C. Konopka, Marie R. Southerland, Michael A. DeBord, Leah P. Shriver, Claire A. Tessier, David A. Hunstad, Wiley J. Youngs, Patrick O. Wagers, Matthew J. Panzner, Kyle T. Whiddon, Kristin M. Tiemann
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 27:764-775
Alkyl- and N,N′-bisnaphthyl-substituted imidazolium salts were tested in vitro for their anti-cancer activity against four non-small cell lung cancer cell lines (NCI–H460, NCI–H1975, HCC827, A549). All compounds had potent anticancer activity w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4c4f602f55c1a16d3b766f90a20c3e5
https://doi.org/10.1016/j.bmcl.2017.01.035
https://doi.org/10.1016/j.bmcl.2017.01.035
Autor:
Michael L. Stromyer, Matthew J. Panzner, Nicholas A. Johnson, Michael A. DeBord, Patrick O. Wagers, Leah P. Shriver, Wiley J. Youngs, Chrys Wesdemiotis, Steven R. Crabtree, Marie R. Southerland, Nicolas Alexander, Claire A. Tessier
Publikováno v:
Bioorg Med Chem
A series of novel bis-imidazolium salts was synthesized, characterized, and evaluated in vitro against a panel of non-small cell lung cancer (NSCLC) cells. Two imidazolium cores were connected with alkyl chains of varying lengths to develop a structu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28f376803925eb84f624f7b8a859532f
https://doi.org/10.1016/j.bmc.2020.115893
https://doi.org/10.1016/j.bmc.2020.115893
Autor:
Radisa Tosanovic, Kerri L. Shelton, Alexandra Taraboletti, Nikki K. Robishaw, Patrick O. Wagers, Claire A. Tessier, Michael A. DeBord, Sailaja Paruchuri, Leah P. Shriver, Wiley J. Youngs, Daniel Paul Jackson, Matthew J. Panzner, William G. Kofron, Marie R. Southerland
Publikováno v:
Tetrahedron. 72:5729-5743
The syntheses and characterization of C4 and C5 substituted N,N′-bis(arylmethyl)imidazolium salts with hydrophilic or lipophilic substituents on the imidazole ring are reported. A structure-activity relationship study revealed that the lipophilicit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5aa67b8b89cc6f779bd3dd1bffddaf15
https://doi.org/10.1016/j.tet.2016.07.068
https://doi.org/10.1016/j.tet.2016.07.068