Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Wiley A. Schell"'
Autor:
Julia R. Palmucci, Blake E. Sells, Charles D. Giamberardino, Dena L. Toffaletti, Baodi Dai, Yohannes G. Asfaw, Laura G. Dubois, Zhong Li, Barbara Theriot, Wiley A. Schell, William Hope, Jennifer L. Tenor, John R. Perfect
Publikováno v:
mBio, Vol 15, Iss 5 (2024)
ABSTRACTInvasive fungal infections are a significant public health concern, with mortality rates ranging from 20% to 85% despite current treatments. Therefore, we examined whether a ketogenic diet could serve as a successful treatment intervention in
Externí odkaz:
https://doaj.org/article/1c4d26c9463d44078161728fc5c59925
Autor:
Charles D. Giamberardino, Wiley A. Schell, Jennifer L. Tenor, Dena L. Toffaletti, John R. Perfect
Publikováno v:
Journal of Fungi, Vol 10, Iss 8, p 520 (2024)
Cryptococcal meningitis (CM) causes significant global morbidity and mortality. Current therapeutic strategies rely on deoxycholated or liposomal forms of the polyene amphotericin B. Nystatin is also a polyene with broad-spectrum antimicrobial activi
Externí odkaz:
https://doaj.org/article/97071ee09cf54f59b5a21e0ffb80f0f2
Autor:
Charles D. Giamberardino, Wiley A. Schell, Jennifer L. Tenor, Dena L. Toffaletti, Julia R. Palmucci, Choiselle Marius, Jane-Valeriane K. Boua, Quinlyn Soltow, Robert Mansbach, M. Arthur Moseley, J. Will Thompson, Laura G. Dubois, William Hope, John R. Perfect, Karen Joy Shaw
Publikováno v:
mBio, Vol 13, Iss 6 (2022)
ABSTRACT Cryptococcal Meningitis (CM) is uniformly fatal if not treated, and treatment options are limited. We previously reported on the activity of APX2096, the prodrug of the novel Gwt1 inhibitor APX2039, in a mouse model of CM. Here, we investiga
Externí odkaz:
https://doaj.org/article/12c94fc2bb48423287573f9192ce65ce
Autor:
Robert Rolfe, Jr., Wiley A. Schell, Becky Smith, Jacob Klapper, John R. Perfect, Julia A. Messina
Publikováno v:
Medical Mycology Case Reports, Vol 29, Iss , Pp 12-14 (2020)
We present a case of an invasive Curvularia infection in a patient who developed following bilateral orthotopic lung transplantation despite receiving post-transplant antifungal prophylaxis. This infection presented as mold colonies studding the inte
Externí odkaz:
https://doaj.org/article/1c5d73b57703438aabc32a7041fa7ac3
Autor:
Syed Mohammed Qasim Hussaini, Deng Madut, Betty C. Tong, Elizabeth N. Pavlisko, Wiley A. Schell, John R. Perfect, Nathan M. Thielman
Publikováno v:
BMC Infectious Diseases, Vol 18, Iss 1, Pp 1-6 (2018)
Abstract Background Blastomycosis is an endemic mycosis in North America that is caused by the dimorphic fungus Blastomyces dermatitidis. The illness is a systemic disease with a wide variety of pulmonary and extra-pulmonary manifestations. The initi
Externí odkaz:
https://doaj.org/article/9e07f0f4785046cbae8f16bf07e70fe5
Autor:
Jacob N. Schroder, Ramesh A Bharadwaj, Michelle Maureen McGauvran, Barbara D. Alexander, Rebekah W. Moehring, Shanti Narayanasamy, Wiley A. Schell, Adam R. Williams, John R. Perfect, Thuy Le
Publikováno v:
Open Forum Infectious Diseases. 8
We report the first case of Curvularia alcornii aortic pseudoaneurysm following bioprosthetic aortic valve replacement in an immunocompetent host. Infection was complicated by septic emboli to multiple organs. Despite aggressive surgical intervention
Autor:
Jacob A. Klapper, Wiley A. Schell, John R. Perfect, Becky Smith, Julia A. Messina, Robert Rolfe
Publikováno v:
Medical Mycology Case Reports, Vol 29, Iss, Pp 12-14 (2020)
Medical Mycology Case Reports
Medical Mycology Case Reports
We present a case of an invasive Curvularia infection in a patient who developed following bilateral orthotopic lung transplantation despite receiving post-transplant antifungal prophylaxis. This infection presented as mold colonies studding the inte
Autor:
Julie Autmizguine, Pablo J. Sánchez, Kristi Prather, Roger Kim, Mark L. Hudak, Kelly C. Wade, Catherine M. Bendel, Dan L. Stewart, Robert E. White, Echezona E. Ezeanolue, Paresh Pandit, Gratias Mundakel, Scott Macgilvray, Jamie Gao, Seetha Shankaran, Shahnaz Duara, Neil N. Finer, Natalie Neu, David J. Burchfield, Barry R. Bloom, Brenda B. Poindexter, David A. Kaufman, Agnes Perenyi, Rune Toms, Margarita Bidegain, Girija Natarajan, Anand Kantak, Daniel K. Benjamin, Jonathan Nedrelow, Karen E. Shattuck, Mohan Pammi, Ramasubbareddy Dhanireddy, Ashley Ross, Phillip Gordon, Antonio Arrieta, Kathleen A. Kennedy, Wiley A. Schell, P. Brian Smith
Objectives Extremely premature infants are at high risk of developing invasive candidiasis; fluconazole prophylaxis is safe and effective for reducing invasive candidiasis in this population but further study is needed. We sought to better understand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4c6d76defadfd03a4ad7ea649cbea95
https://europepmc.org/articles/PMC6927883/
https://europepmc.org/articles/PMC6927883/
Autor:
Jennifer L. Tenor, Jonathan Covel, Mili Kapoor, Michael Trzoss, Charles Giamberardino, John R. Perfect, Wiley A. Schell, Molly K. Moloney, Peter Webb, Quinlyn A. Soltow, Karen Joy Shaw, Gisele Duboc, Dena L. Toffaletti
Publikováno v:
Antimicrobial Agents and Chemotherapy
Cryptococcal meningitis (CM), caused primarily by Cryptococcus neoformans, is uniformly fatal if not treated. Treatment options are limited, especially in resource-poor geographical regions, and mortality rates remain high despite current therapies.<
Autor:
Nathan M. Thielman, Syed Mohammed Qasim Hussaini, Elizabeth N. Pavlisko, Wiley A. Schell, John R. Perfect, Deng B. Madut, Betty C. Tong
Publikováno v:
BMC Infectious Diseases, Vol 18, Iss 1, Pp 1-6 (2018)
BMC Infectious Diseases
BMC Infectious Diseases
Background Blastomycosis is an endemic mycosis in North America that is caused by the dimorphic fungus Blastomyces dermatitidis. The illness is a systemic disease with a wide variety of pulmonary and extra-pulmonary manifestations. The initial presen