Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Wilco P. Pulskens"'
Autor:
Nike Claessen, Wilco P. Pulskens, Melissa Uil, Chi M. Hau, Gerrie Nieuwenhuizen, Frederike J. Bemelman, Marcel. P. B. Jansen, Dorien Standaar, Jaklien C. Leemans, Joris J. T. H. Roelofs, Rienk Nieuwland, Sandrine Florquin
Publikováno v:
Nephrology, dialysis, transplantation, 35(8), 1320-1327. Oxford University Press
Background Ischaemia-reperfusion (IR) injury is an important determinant of delayed graft function (DGF) affecting allograft function. Mitochondrial DNA (mtDNA) is released upon cell death and platelet activation into the extracellular environment an
Autor:
Wilco P Pulskens, Melissa Verkaik, Fareeba Sheedfar, Ellen P van Loon, Bart van de Sluis, Mark G Vervloet, Joost G Hoenderop, René J Bindels, NIGRAM Consortium
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142510 (2015)
Impaired mineral homeostasis and inflammation are hallmarks of chronic kidney disease (CKD), yet the underlying mechanisms of electrolyte regulation during CKD are still unclear. Here, we applied two different murine models, partial nephrectomy and a
Externí odkaz:
https://doaj.org/article/1dae194f46cf4180a54c7c04a6a512c1
Autor:
Wilco P Pulskens, Loes M Butter, Gwendoline J Teske, Nike Claessen, Mark C Dessing, Richard A Flavell, Fayyaz S Sutterwala, Sandrine Florquin, Jaklien C Leemans
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85775 (2014)
Progressive renal disease is characterized by tubulo-interstitial injury with ongoing inflammation and fibrosis. The Nlrp3 inflammasome contributes to these pathophysiological processes through its canonical effects in cytokine maturation. Nlrp3 may
Externí odkaz:
https://doaj.org/article/0524e48a0d334abe8297ad94bf16c189
Autor:
Wilco P. Pulskens, Charles A. Dinarello, Luuk B. Hilbrands, M.A.H. Bakker-van Bebber, J. van der Vlag, Mihai G. Netea, M. Kouwenberg, Laura E. Diepeveen
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0251809 (2021)
PLoS One, 16
PLoS One, 16, 5
PLoS ONE
PLoS One, 16
PLoS One, 16, 5
PLoS ONE
Contains fulltext : 235331.pdf (Publisher’s version ) (Open Access) The dendritic cell (DC)-derived cytokine profile contributes to naive T cell differentiation, thereby directing the immune response. IL-37 is a cytokine with anti-inflammatory char
Autor:
Hamid Aslami, Wilco P Pulskens, Maria T Kuipers, Aafkeline P Bos, André B P van Kuilenburg, Ronald J A Wanders, Jeroen Roelofsen, Joris J T H Roelofs, Raphaela P Kerindongo, Charlotte J P Beurskens, Marcus J Schultz, Wim Kulik, Nina C Weber, Nicole P Juffermans
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63497 (2013)
Sepsis is characterized by a generalized inflammatory response and organ failure, associated with mitochondrial dysfunction. Hydrogen sulfide donor NaHS has anti-inflammatory properties, is able to reduce metabolism and can preserve mitochondrial mor
Externí odkaz:
https://doaj.org/article/66d0b4d10b034ee9a477c87e096ffef5
Autor:
Coert J Zuurbier, Willeke M C Jong, Otto Eerbeek, Anneke Koeman, Wilco P Pulskens, Loes M Butter, Jaklien C Leemans, Markus W Hollmann
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40643 (2012)
Recent studies indicate that the innate immune system is not only triggered by exogenous pathogens and pollutants, but also by endogenous danger signals released during ischemia and necrosis. As triggers for the innate immune NLRP3 inflammasome prote
Externí odkaz:
https://doaj.org/article/a94404d28503471b94ce215442b01358
Autor:
Jaklien C. Leemans, Nicole P. Juffermans, Sandrine Florquin, Joris J. T. H. Roelofs, Loes M. Butter, Marcel. P. B. Jansen, Wilco P. Pulskens
Publikováno v:
Shock (Augusta, Ga.), 49(3), 301-310. Lippincott Williams and Wilkins
Systemic inflammatory response syndrome (SIRS) is characterized by the activation of the innate immune system resulting in stimulation of inflammatory responses, coagulation, and platelet activation that may contribute to complication such as the dev
Autor:
Wilco P Pulskens, Gwendoline J Teske, Loes M Butter, Joris J Roelofs, Tom van der Poll, Sandrine Florquin, Jaklien C Leemans
Publikováno v:
PLoS ONE, Vol 3, Iss 10, p e3596 (2008)
Toll-like receptors (TLRs) can detect endogenous danger molecules released upon tissue injury resulting in the induction of a proinflammatory response. One of the TLR family members, TLR4, is constitutively expressed at RNA level on renal epithelium
Externí odkaz:
https://doaj.org/article/7fda4bf1189c4ccd90d0c5f09f205f3a
Autor:
Jaklien C. Leemans, Alessandra Tammaro, Sandrine Florquin, Johannes Roth, Tom van der Poll, Wilco P. Pulskens, Thomas Vogl, Loes M. Butter, Gwendoline J. D. Teske, Marco van Eijk, Mark C. Dessing, Nike Claessen
Publikováno v:
Kidney International. Supplement, 87, 85-94
Kidney international, 87(1), 85-94. Nature Publishing Group
Kidney International. Supplement, 87, 1, pp. 85-94
Kidney international, 87(1), 85-94. Nature Publishing Group
Kidney International. Supplement, 87, 1, pp. 85-94
Item does not contain fulltext Upon ischemia/reperfusion (I/R)-induced injury, several damage-associated molecular patterns are expressed including the calcium-binding protein S100A8/A9 complex. S100A8/A9 can be recognized by Toll-like receptor-4 and
Autor:
Eline A. E. van der Hagen, Wilco P. Pulskens, Ellen P. M. van Loon, Joost G. J. Hoenderop, René J. M. Bindels, Marla Lavrijsen, Marc G. Vervloet, Harry van Goor
Publikováno v:
American Journal of Physiology : Renal Physiology, 309, F359-68
American Journal of Physiology. Renal Physiology, 309(4), F359-F368. American Physiological Society
American journal of physiology-Renal physiology, 309(4), F359-F368. AMER PHYSIOLOGICAL SOC
van Loon, E P M, Pulskens, W P, van der Hagen, E A E, Lavrijsen, M, Vervloet, M G, van Goor, H, Bindels, R J M & Hoenderop, J G J 2015, ' Shedding of klotho by ADAMs in the kidney ', American Journal of Physiology. Renal Physiology, vol. 309, no. 4, pp. F359-F368 . https://doi.org/10.1152/ajprenal.00240.2014
American Journal of Physiology : Renal Physiology, 309, 4, pp. F359-68
American Journal of Physiology. Renal Physiology, 309(4), F359-F368. American Physiological Society
American journal of physiology-Renal physiology, 309(4), F359-F368. AMER PHYSIOLOGICAL SOC
van Loon, E P M, Pulskens, W P, van der Hagen, E A E, Lavrijsen, M, Vervloet, M G, van Goor, H, Bindels, R J M & Hoenderop, J G J 2015, ' Shedding of klotho by ADAMs in the kidney ', American Journal of Physiology. Renal Physiology, vol. 309, no. 4, pp. F359-F368 . https://doi.org/10.1152/ajprenal.00240.2014
American Journal of Physiology : Renal Physiology, 309, 4, pp. F359-68
Contains fulltext : 153960.pdf (Publisher’s version ) (Closed access) The anti-aging gene klotho plays an important role in Ca(2+) and phosphate homeostasis. Membrane-bound klotho is an essential coreceptor for fibroblast growth factor-23 and can b