Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Wilbur H Chen"'
Autor:
Rahsan Erdem, Gwen Ambler, Mohamed Al-Ibrahim, Katarzyna Fraczek, Steven D Dong, Christopher Gast, Laina D Mercer, Michael Raine, Sharon M Tennant, Wilbur H Chen, Eugenio L de Hostos, Robert K M Choy
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 11, p e0009969 (2021)
Cholera remains a major cause of infectious diarrhea globally. Despite the increased availability of cholera vaccines, there is still an urgent need for other effective interventions to reduce morbidity and mortality. Furthermore, increased prevalenc
Externí odkaz:
https://doaj.org/article/3eb98ede54d04b3a96edfa0752e351a9
Autor:
Motaher Hossain, Kamrul Islam, Meagan Kelly, Leslie M Mayo Smith, Richelle C Charles, Ana A Weil, Taufiqur Rahman Bhuiyan, Pavol Kováč, Peng Xu, Stephen B Calderwood, Jakub K Simon, Wilbur H Chen, Michael Lock, Caroline E Lyon, Beth D Kirkpatrick, Mitchell Cohen, Myron M Levine, Marc Gurwith, Daniel T Leung, Andrew S Azman, Jason B Harris, Firdausi Qadri, Edward T Ryan
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 11, p e0007874 (2019)
BackgroundAntibodies targeting O-specific polysaccharide (OSP) of Vibrio cholerae may protect against cholera; however, little is known about this immune response in infected immunologically naïve humans.MethodologyWe measured serum anti-OSP antibod
Externí odkaz:
https://doaj.org/article/916ab507d03948078640a876d62ccc61
Autor:
Tonya M Santaus, Shan Li, Lahari Saha, Wilbur H Chen, Siya Bhagat, O Colin Stine, Chris D Geddes
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0220102 (2019)
The ability for safe and rapid pathogenic sample transportation and subsequent detection is an increasing challenge throughout the world. Herein, we describe and use bead-beating, vortex, sonication, 903 protein saver cards, and Lyse-It methods, aimi
Externí odkaz:
https://doaj.org/article/2bafc6d4f6874f41af329aa36138b88d
Autor:
Kamrul Islam, Motaher Hossain, Meagan Kelly, Leslie M Mayo Smith, Richelle C Charles, Taufiqur Rahman Bhuiyan, Pavol Kováč, Peng Xu, Regina C LaRocque, Stephen B Calderwood, Jakub K Simon, Wilbur H Chen, Douglas Haney, Michael Lock, Caroline E Lyon, Beth D Kirkpatrick, Mitchell Cohen, Myron M Levine, Marc Gurwith, Jason B Harris, Firdausi Qadri, Edward T Ryan
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 4, p e0006376 (2018)
BACKGROUND:Cholera is an acute voluminous dehydrating diarrheal disease caused by toxigenic strains of Vibrio cholerae O1 and occasionally O139. A growing body of evidence indicates that immune responses targeting the O-specific polysaccharide (OSP)
Externí odkaz:
https://doaj.org/article/5a7a697cf70e4170a1b24a53b409d81b
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 1, p e0005291 (2017)
Enterotoxigenic Escherichia coli (ETEC) is a non-invasive enteric pathogen of considerable public health importance, being one of the most common attributable causes of diarrheal illness in infants and young children in developing countries and the m
Externí odkaz:
https://doaj.org/article/8b4c1c04b6c047e594fb7fcfbd140269
Autor:
Wilbur H. Chen, Joelle Woolston, Silvia Grant-Beurmann, Courtney K. Robinson, Garima Bansal, Joseph Nkeze, Jasnehta Permala-Booth, Claire M. Fraser, Sharon M. Tennant, Mallory C. Shriver, Marcela F. Pasetti, Yuanyuan Liang, Karen L. Kotloff, Alexander Sulakvelidze, Jennifer A. Schwartz
Publikováno v:
Antibiotics, Vol 13, Iss 9, p 858 (2024)
Bacterial diseases of the gastrointestinal (GI) tract continue to be a major worldwide cause of human morbidity and mortality. Among various enteric pathogens, Shigella spp. are some of the most common and deadly bacterial pathogens. They are respons
Externí odkaz:
https://doaj.org/article/f228fda926f54c15bcfb2837bfeed2bd
Autor:
Hyung-Joon Kwon, Martina Kosikova, Weichun Tang, Uriel Ortega-Rodriguez, Peter Radvak, Ruoxuan Xiang, Kelly E. Mercer, Levan Muskhelishvili, Kelly Davis, Jerrold M. Ward, Ivan Kosik, Jaroslav Holly, Insung Kang, Jonathan W. Yewdell, Ewan P. Plant, Wilbur H. Chen, Mallory C. Shriver, Robin S. Barnes, Marcela F. Pasetti, Bin Zhou, David E. Wentworth, Hang Xie
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105507- (2022)
Summary: Here we interrogate the factors responsible for SARS-CoV-2 breakthrough infections in a K18-hACE2 transgenic mouse model. We show that Delta and the closely related Kappa variant cause viral pneumonia and severe lung lesions in K18-hACE2 mic
Externí odkaz:
https://doaj.org/article/f958b51bb99d4ff58bffab752bca1d75
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 15, Iss 6, Pp 1357-1378 (2019)
Enterotoxigenic Escherichia coli (ETEC) is a major cause of travelers’ diarrhea and of diarrhea among young children in developing countries. Experimental challenge studies in adult volunteers have played a pivotal role in establishing ETEC as an e
Externí odkaz:
https://doaj.org/article/b171ee2dce2c4eb285100a53b3536571
Autor:
Kirsten E Wiens, Anita S Iyer, Taufiqur R Bhuiyan, Lenette L Lu, Deniz Cizmeci, Matthew J Gorman, Dansu Yuan, Rachel L Becker, Edward T Ryan, Stephen B Calderwood, Regina C LaRocque, Fahima Chowdhury, Ashraful I Khan, Myron M Levine, Wilbur H Chen, Richelle C Charles, Andrew S Azman, Firdausi Qadri, Galit Alter, Jason B Harris
Publikováno v:
The Lancet Microbe. 4:e228-e235
Publikováno v:
Expert Review of Vaccines, Vol 16, Iss 3, Pp 197-213 (2017)
Introduction: Cholera remains a problem in developing countries and a risk for travelers. Hypochlorhydria, blood group O, cardiac and renal disease increase the risk of developing cholera gravis. Oral vaccines containing inactivated Vibrio cholerae a
Externí odkaz:
https://doaj.org/article/835fdf3a8a794bfa8376c16df19d275b