Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Wiktor Banachewicz"'
Publikováno v:
Proceedings of the National Academy of Sciences. 108:5596-5601
Members of the homeodomain superfamily are three-helix bundle proteins whose second and third helices form a helix-turn-helix motif (HTH). Their folding mechanism slides from the ultrafast, three-state framework mechanism for the engrailed homeodomai
Publikováno v:
Science. 329:1312-1316
Transient Protein Conformations Transient conformations are important to protein function; however, detecting and characterizing these states is technically challenging. Korzhnev et al. (p. 1312 ; see the Perspective by Al-Hashimi ) combined recently
Publikováno v:
British Journal of Pharmacology. 141:497-507
We have previously shown that, in glioma C6 cells, two nucleotide ADP-sensitive receptors coexist: P2Y1, coupled to PLC and responsible for Ca2+ release, and P2Y12, negatively coupled to adenylate cyclase. In the present study, we examined the effect
Current questions in protein folding mechanisms include how fast can a protein fold and are there energy barriers for the folding and unfolding of ultrafast folding proteins? The small 3-helical engrailed homeodomain protein folds in 1.7 μs to form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b967d62684799ccc63278b0ba95aeb6f
https://europepmc.org/articles/PMC3021018/
https://europepmc.org/articles/PMC3021018/
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 107(51)
Small proteins can fold remarkably rapidly, even in μ s. What limits their rate of folding? The Engrailed homeodomain is a particularly well-characterized example, which folds ultrafast via an intermediate, I, of solved structure. It is a puzzle tha
Publikováno v:
Collection Symposium Series.
Publikováno v:
Collection Symposium Series.
Publikováno v:
Purinergic Signalling
In developing muscle cells environmental stimuli transmitted by purines binding to the specific receptors are crucial proliferation regulators. C2C12 myoblasts express numerous purinergic receptors representing both main classes: P2X and P2Y. Among P