Ace inhibitors and cardiovascular regulation the importance of autocrine and paracrine mechanisms

Autor: Wijngaarden, Jan van.

Proefschrift Rijksuniversiteit Groningen.
Met lit.opg. - Met samenvatting in het Nederlands.

Externí odkaz: http://irs.ub.rug.nl/ppn/298212978

Myeloperoxidase Inhibition in Heart Failure With Preserved or Mildly Reduced Ejection Fraction: SATELLITE Trial Results

Autor: Lam, Carolyn S P, Lund, Lars H, Shah, Sanjiv J, Voors, Adriaan A, Erlinge, David, Saraste, Antti, Pirazzi, Carlo, Grove, Erik L, Barasa, Anders, Schou, Morten, Aziz, Ahmed, Svedlund, Sara, Wijngaarden, Jan VAN, Lindstedt, Eva-Lotte, Gustavsson, Andreas, Nelander, Karin, Garkaviy, Pavlo, Gan, Li-Ming, Gabrielsen, Anders

Publikováno v: Lam, C S P, Lund, L H, Shah, S J, Voors, A A, Erlinge, D, Saraste, A, Pirazzi, C, Grove, E L, Barasa, A, Schou, M, Aziz, A, Svedlund, S, Wijngaarden, J VAN, Lindstedt, E-L, Gustavsson, A, Nelander, K, Garkaviy, P, Gan, L-M & Gabrielsen, A 2023, ' Myeloperoxidase Inhibition in Heart Failure With Preserved or Mildly Reduced Ejection Fraction : SATELLITE Trial Results ', Journal of Cardiac Failure . https://doi.org/10.1016/j.cardfail.2023.04.003

BACKGROUND: Inflammation is a key driver of heart failure (HF) with preserved left ventricular ejection fraction (LVEF). AZD4831 inhibits extracellular myeloperoxidase, reduces inflammation and improves microvascular function in preclinical disease m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::763df7acd2f82147099403eedb6c232b
https://doi.org/10.1016/j.cardfail.2023.04.003

Ace inhibitors and cardiovascular regulation: the importance of autocrine and paracrine mechanisms

Autor: Wijngaarden, Jan van

As demonstrated in a large number of clinical studies, angiotensin converting enzyme (ACE) inhibitors are of great value for the treatment of cardiovascular disorders. Although the clinical merits of these drugs are now well recognized, their mechani

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::170e0cddb0c4aa0e20984a9b0250f5e1
https://research.rug.nl/en/publications/8692e7ec-8b89-4cf6-87fb-7e715d88b1c2