Altered age‐linked regulation of plasma DYRK1A in elderly cognitive complainers (INSIGHT‐preAD study) with high brain amyloid load

Autor: Jean M. Delabar, Marion Ortner, Stephanie Simon, Anne Wijkhuisen, Cecile Feraudet‐Tarisse, Jonathan Pegon, Emma Vidal, Yael Hirschberg, Bruno Dubois, Marie‐Claude Potier

Publikováno v: Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 6, Iss 1, Pp n/a-n/a (2020)

Abstract Introduction An effective therapy has not yet been developed for Alzheimer's disease (AD), in part because pathological changes occur years before clinical symptoms manifest. We recently showed that decreased plasma DYRK1A identifies individ

Externí odkaz: https://doaj.org/article/78824974b0234847bd01a264b6d1fc28

Evaluation of In-Flow Magnetoresistive Chip Cell—Counter as a Diagnostic Tool

Autor: Manon Giraud, François-Damien Delapierre, Anne Wijkhuisen, Pierre Bonville, Mathieu Thévenin, Gregory Cannies, Marc Plaisance, Elodie Paul, Eric Ezan, Stéphanie Simon, Claude Fermon, Cécile Féraudet-Tarisse, Guénaëlle Jasmin-Lebras

Publikováno v: Biosensors, Vol 9, Iss 3, p 105 (2019)

Inexpensive simple medical devices allowing fast and reliable counting of whole cells are of interest for diagnosis and treatment monitoring. Magnetic-based labs on a chip are one of the possibilities currently studied to address this issue. Giant ma

Externí odkaz: https://doaj.org/article/01844057710541ba8b9c2047a29ef282

Evaluation of Anti-Cancer Effects of Lycopene extracted from Pink Guava Psidium guajava L. and its Combination with Apigenin or Resveratrol

Autor: Anne Wijkhuisen, Odile Marcelin, Fabienne Priam, Roselyne Marcus, Emilie Juliette Smith-Ravin

Background Active biomolecules extracted from plant biodiversity appear to offer an alternative to the frequently toxic chemotherapy methods used to treat cancer. The micronutrients obtained from certain fruits, including pink guava Psidium guajava L

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::65c9f80ff5847a421fab5af777b9f29a
https://doi.org/10.21203/rs.3.rs-626677/v1

Curative properties of antibodies against prion protein: A comparative in vitro study of monovalent fragments and divalent antibodies

Autor: Alexandrenne, Coralie, Hanoux, Vincent, Dkhissi, Fatima, Boquet, Didier, Couraud, Jean-Yves, Wijkhuisen, Anne

Publikováno v: In Journal of Neuroimmunology 2009 209(1):50-56

Characterization of a highly neutralizing single monoclonal antibody to botulinum neurotoxin type A

Autor: Christine Rasetti-Escargueil, Anne Wijkhuisen, Emmanuel Lemichez, Stéphanie Simon, Michel R. Popoff, Sébastien Brier, Maud Marechal

Publikováno v: FASEB Journal
FASEB Journal, 2021, 35 (5), ⟨10.1096/fj.202002492R⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2021, 35 (5), ⟨10.1096/fj.202002492R⟩

International audience; Compared to conventional antisera strategies, monoclonal antibodies (mAbs) represent an alternative and safer way to treat botulism, a fatal flaccid paralysis due to botulinum neurotoxins (BoNTs). In addition, mAbs offer the a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fa47619ad51c6b2afa7f5b8e8b27e30
https://pubmed.ncbi.nlm.nih.gov/33817838