Zobrazeno 1 - 10
of 228
pro vyhledávání: '"Wightman, R M"'
Autor:
Wightman, R. M., Jankowski, J. A., Kennedy, R. T., Kawagoe, K. T., Schroeder, T. J., Leszczyszyn, D. J., Near, J. A., Diliberto,, E. J., Viveros, O. H.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1991 Dec 01. 88(23), 10754-10758.
Externí odkaz:
https://www.jstor.org/stable/2358330
Autor:
Wightman, R. M., Millan, J. L., King, I. F., Yadav, M. C., Street, S. E., Zylka, M. J., Taylor-Blake, B., Walsh, P. L., Kramer, N. J., Vihko, P.
Prostatic acid phosphatase (PAP) and ecto-5′-nucleotidase (NT5E) hydrolyze extracellular AMP to adenosine in dorsal root ganglia (DRG) neurons and in the dorsal spinal cord. Previously, we found that adenosine production was reduced, but not elimin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfcda2ab71fc912c71d717218bbffc94
Dopamine and serotonin (5-hydroxytryptamine or 5-HT) are neurotransmitters that are implicated in many psychological disorders. Although dopamine transmission in the brain has been studied extensively in vivo with fast scan cyclic voltammetry, detect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b43ea61a9bc55f1ecd1553d2ae1d092
The mesolimbic dopamine projection from the ventral tegmental area (VTA) to the nucleus accumbens (NAc) is critical in mediating reward-related behaviors, but the precise role of dopamine in this process remains unknown. We completed a series of stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5fe4ad412590c072b744d0b585796b1
Synapsins are a family of synaptic vesicle proteins that are important for neurotransmitter release. Here we have used triple knockout (TKO) mice lacking all three synapsin genes to determine the roles of synapsins in the release of two monoamine neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d4c716906cb67c8e4a8130413592b18
Fast-scan cyclic voltammetry (FSCV) at carbon-fiber microelectrodes has been used to demonstrate that sub-second changes in catecholamine concentration occur within the nucleus accumbens (NAc) shell during motivated behaviors, and these fluctuations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31136699d7605d24bc8f52631aa7b1a0
Publikováno v:
Journal of Biological Chemistry. 267:18329-18335
Secretion of catecholamines from individual bovine adrenal medullary cells grown in primary culture has been investigated with a carbon-fiber microelectrode placed adjacent to the cells. Oxidation of catecholamines at the electrode surface results in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b206d334a9eb13b6affb03715137f87
https://doi.org/10.1016/s0021-9258(19)36964-9
https://doi.org/10.1016/s0021-9258(19)36964-9
Dopamine in the nucleus accumbens (NAc) is an important neurotransmitter for reward-seeking behaviors such as intracranial self-stimulation (ICSS), although its precise role remains unclear. Here, dynamic fluctuations in extracellular dopamine were m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16b2ddb7ff2ab8a2bff22fdbb8a60488
Autor:
Cleaveland, N. A., Wightman, R. M., Carelli, R. M., Day, J. J., Stuber, G. D., Aragona, B. J.
Preferential enhancement of dopamine transmission within the nucleus accumbens (NAc) shell is a fundamental aspect of the neural regulation of cocaine reward. Despite its importance, the nature of this effect is poorly understood. Here, we used fast-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03e520a102e1122ecd05dc5b4b6afaea
Autor:
Holmstrand, E., Medvedev, I. O., Murphy, K., Nicholls, P. J., Gainetdinov, R. R., Wong, L., Ghisi, V., Caron, M. G., Sotnikova, T. D., Sesack, S. R., Salahpour, A., Kile, B., Ramsey, A. J., Wightman, R. M.
The dopamine transporter (DAT) plays a key role in the regulation of dopaminergic signaling wherein it controls both the spatial and temporal actions of dopamine. Here we evaluated the behavioral and neurochemical consequences of increased DAT functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cf159a13e3371e898ca6cb23bbd0e34