Establishment of HIV-1 latency in resting CD4⁺ T cells depends on chemokine-induced changes in the actin cytoskeleton

Autor: Cameron, Paul U., Saleh, Suha, Sallmann, Georgina, Solomon, Ajantha, Wightman, Fiona, Evans, Vanessa A., Boucher, Genevieve, Haddad, Elias K., Sekaly, Rafick-Pierre, Harman, Andrew N., Anderson, Jenny L., Jones, Kate L., Mak, Johnson, Cunningham, Anthony L., Jaworowski, Anthony, Lewin, Sharon R.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2010 Sep . 107(39), 16934-16939.

Externí odkaz: https://www.jstor.org/stable/20779889

Expression and reactivation of HIV in a chemokine induced model of HIV latency in primary resting CD4+ T cells

Autor: Khoury Gabriela, Kumar Nitasha, Alexander Marina, Ramanayake Saumya, Wightman Fiona, Saleh Suha, Pereira Cândida, Purcell Damian, Cameron Paul U, Lewin Sharon R

Publikováno v: Retrovirology, Vol 8, Iss 1, p 80 (2011)

Abstract Background We recently described that HIV latent infection can be established in vitro following incubation of resting CD4+ T-cells with chemokines that bind to CCR7. The main aim of this study was to fully define the post-integration blocks

Externí odkaz: https://doaj.org/article/e26c04ca46c540d9808a04ed339d5705

No adverse safety or virological changes two years following vorinostat in HIV-infected individuals on antiretroviral therapy

Autor: MOTA, Talia M, RASMUSSEN, Thomas A, RHODES, Ajantha, TENNAKOON, Surekha, DANTANARAYANA, Ashanti, WIGHTMAN, Fiona, HAGENAUER, Michelle, RONEY, Janine, SPELMAN, Tim, PURCELL, Damian FJ, McMAHON, James, HOY, Jennifer F, PRINCE, H. Miles, ELLIOTT, Julian H, LEWIN, Sharon R

Publikováno v: Mota, T M, Rasmussen, T A, Rhodes, A, Tennakoon, S, Dantanarayana, A, Wightman, F, Hagenauer, M, Roney, J, Spelman, T, Purcell, D F J, McMahon, J, Hoy, J F, Prince, H M, Elliott, J H & Lewin, S R 2017, ' No adverse safety or virological changes two years following vorinostat in HIV-infected individuals on antiretroviral therapy ', AIDS . https://doi.org/10.1097/QAD.0000000000001442

OBJECTIVE: To determine the long term effects of vorinostat on safety and virological parameters in HIV-infected individuals on suppressive antiretroviral therapy (ART).DESIGN: Prospective longitudinal observational extended follow up of 20 HIV-infec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::67ddc6040ff87095d153efc9b1c30bb8
https://pure.au.dk/portal/da/publications/no-adverse-safety-or-virological-changes-two-years-following-vorinostat-in-hivinfected-individuals-on-antiretroviral-therapy(9b0b3099-b3f3-44b6-9626-b681eb6c2e25).html

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