Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Wiggert J, Altenburg"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Encapsulins are recently discovered protein compartments able to specifically encapsulate cargo proteins in vivo. Encapsulation is dependent on C-terminal targeting peptides (TPs). Here, we characterize and engineer TP-shell interactions in
Externí odkaz:
https://doaj.org/article/91c356a784e24cafbcf78672c4a1ab34
Autor:
Wiggert J. Altenburg, N. Amy Yewdall, Daan F. M. Vervoort, Marleen H. M. E. van Stevendaal, Alexander F. Mason, Jan C. M. van Hest
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Mimicking the crowded cytosol of cells in synthetic cells has been a major limitation to the functionality. Here, the authors used the interaction between nickel, nitrilotriacetic acid and histidine tagged proteins to control loading of macromolecule
Externí odkaz:
https://doaj.org/article/2f279e085191415dabac0fab918c9cf7
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
Compartmentalization of proteins can potentially increase the productivity of engineered metabolic pathways. Here the authors use encapsulins to build non-endogenous organelles in Saccharomyces cerevisiae.
Externí odkaz:
https://doaj.org/article/8acf6e9857834d91a3d30674051ecf08
Autor:
Thijs W. van Veldhuisen, Wiggert J. Altenburg, Madelief A. M. Verwiel, Lenne J. M. Lemmens, Alexander F. Mason, Maarten Merkx, Luc Brunsveld, Jan C. M. van Hest
Publikováno v:
Advanced Materials.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17d271f33965c989e49ea88cf367c696
https://doi.org/10.1002/adma.202300947
https://doi.org/10.1002/adma.202300947
Autor:
Tsuyoshi Mashima, Marleen H. M. E. van Stevendaal, Femke R. A. Cornelissens, Alexander F. Mason, Bas J. H. M. Rosier, Wiggert J. Altenburg, Koji Oohora, Shota Hirayama, Takashi Hayashi, Jan C. M. van Hest, Luc Brunsveld
Publikováno v:
Angewandte Chemie-International Edition, 61(17):e202115041. Wiley
The regulation of protein uptake and secretion is crucial for (inter)cellular signaling. Mimicking these molecular events is essential when engineering synthetic cellular systems. A first step towards achieving this goal is obtaining control over the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4609e9477d71a4e81daa23bd7cc3178c
https://pubmed.ncbi.nlm.nih.gov/35133040
https://pubmed.ncbi.nlm.nih.gov/35133040
Autor:
Wiggert J. Altenburg, Daan F. M. Vervoort, Jan C. M. van Hest, Loai K. E. A. Abdelmohsen, N. Amy Yewdall, Alexander F. Mason, Suzanne B. P. E. Timmermans, Bastiaan C. Buddingh
Publikováno v:
ChemBioChem, 20(20), 2643-2652. Wiley-VCH Verlag
ChemBioChem
Chembiochem
ChemBioChem
Chembiochem
The bottom‐up construction of cell mimics has produced a range of membrane‐bound protocells that have been endowed with functionality and biochemical processes reminiscent of living systems. The contents of these compartments, however, experience
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f725f0f81d17fa5ee215a84da1ead77f
http://www.scopus.com/inward/record.url?scp=85070974230&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85070974230&partnerID=8YFLogxK
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reports, 11(1):4951. Nature Publishing Group
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reports, 11(1):4951. Nature Publishing Group
Encapsulins are recently discovered protein compartments able to specifically encapsulate cargo proteins in vivo. Encapsulation is dependent on C-terminal targeting peptides (TPs). Here, we characterize and engineer TP-shell interactions in the Therm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a22d4b765c7c0ed1867aa8e0aac00f02
http://europepmc.org/articles/PMC7925596
http://europepmc.org/articles/PMC7925596
Autor:
Alexander F, Mason, Wiggert J, Altenburg, Shidong, Song, Marleen, van Stevendaal, Jan C M, van Hest
Publikováno v:
Methods in enzymology. 646
The utilization of liquid-liquid phase separated systems has seen increased attention as synthetic cell platforms due to their innate ability to sequester interesting, functional, and biologically relevant materials. However, their applications are l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9aeacac34b01e0b0c6c1d7ffa2e297c9
https://pubmed.ncbi.nlm.nih.gov/33453933
https://pubmed.ncbi.nlm.nih.gov/33453933
Autor:
Marleen H. M. E. van Stevendaal, Daan F. M. Vervoort, Jan C. M. van Hest, Alexander F. Mason, Wiggert J. Altenburg, N. Amy Yewdall
Publikováno v:
Nature Communications
Nature Communications, 11(1):6282. Nature Publishing Group
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature Communications, 11(1):6282. Nature Publishing Group
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
The cell cytosol is crowded with high concentrations of many different biomacromolecules, which is difficult to mimic in bottom-up synthetic cell research and limits the functionality of existing protocellular platforms. There is thus a clear need fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::502d18763635f436aefa27fcf3aae018
http://europepmc.org/articles/PMC7722712
http://europepmc.org/articles/PMC7722712
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
Nature Communications
Nature Communications
Compartmentalization of proteins into organelles is a promising strategy for enhancing the productivity of engineered eukaryotic organisms. However, approaches that co-opt endogenous organelles may be limited by the potential for unwanted crosstalk a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a32e2f0859bd5dbd26d59ae50d28661
https://doaj.org/article/8acf6e9857834d91a3d30674051ecf08
https://doaj.org/article/8acf6e9857834d91a3d30674051ecf08