Zobrazeno 1 - 6 of 6 pro vyhledávání: '"Wigberto J. Hernandez"'
1
Toxicity and Apoptosis Related Effects of Benzimidazo [3,2-α] Quinolinium Salts Upon Human Lymphoma Cells
Autor: Christian Velez, Ana I. Ortiz-Colón, Karoline Rios, Luz Silva, Beatriz Zayas, Luis A. Rivera, Osvaldo Cox, Jessica Soto, Wigberto J. Hernandez
Publikováno v: The Open Medicinal Chemistry Journal
Objectives: The present study evaluates novel cationic quinoline derivatives known as benzimidazo[3,2-a]quinolinium salts (BQS) named NBQ-48 and ABQ-48 that have structural similarities to known anti-cancer substances such as ellipticine and berberin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f72f5ab19803cd9f330d410e3a99447
https://doi.org/10.2174/1874104501711010054
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3
Comparison of the nucleic acid covalent binding capacity of two nitro-substituted benzazolo[3,2-a]quinolinium salts upon enzymatic reduction
Autor: Osvaldo Cox, Beatriz Zayas, Wigberto J. Hernandez, Marisol Cordero, Maria Terron, Antonio E. Alegria, Juan Beyley
Publikováno v: Toxicology in Vitro. 21:1155-1164
The DNA binding capacity of two nitro-substituted benzazolo[3,2-a]quinolinium chlorides (NBQs), NBQ-38 and NBQ-95, was evaluated upon their enzymatic reduction with hypoxanthine (HX)/xanthine oxidase (XO) under anaerobic conditions. In the presence o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30ef62d7be508becf066e2a75fb4cb59
https://doi.org/10.1016/j.tiv.2007.03.004
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4
Crystal and molecular structure of (Z)-2-(1,3-benzothiazol-2-yl)-2-(6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ylidene)ethanonitrile
Autor: Yan Gao, Osvaldo Cox, Wigberto J. Hernandez, Yong J. Li
Publikováno v: Journal of Crystallographic and Spectroscopic Research. 23:825-828
The title compound C20H16N2S is crystallized in the monoclinic space groupP21/c with cell parametersa=10.663(4),b=17.585(9),c=9.418(5)A,β=115.23°(4),V=1598(3)A3,Z=4. The structure was refined by full-matrix least-squares methods using X-ray data se
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ea1af3c251831497e2e415b218c77e5e
https://doi.org/10.1007/bf01247248
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5
Crystal and molecular structure of 2-(1,3-benzothiazol-2-yl)-2-(4-tert-butylcyclohexylidene)ethanonitrile
Autor: Wigberto J. Hernandez, Osvaldo Cox, Fei Wu, Yong J. Li
Publikováno v: Journal of Crystallographic and Spectroscopic Research. 23:645-648
The crystal and molecular structure of the title compound (C19H22N2S) has been investigated by single crystal X-ray methods. The crystals are orthorhombic, space groupPbca, with cell dimensions:a=12.082(2)A,b=11.460(2)A,c=25.128(4)A. The structure wa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b8526efa45f285fc3b22f8d4bfdc2b86
https://doi.org/10.1007/bf01325188
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6
1-(1,3-Benzothiazol-2-yl)-2-(2-bromo-5-nitrophenyl)ethanone
Autor: Wigberto J. Hernandez, T. Ruiwu, D. Cardona, Osvaldo Cox, C. L. Barnes, S. D. Huang
Publikováno v: Acta crystallographica. Section C, Crystal structure communications. 53
The title compound, C15H9BrN2O3S, was isolated as an unexpected product from the reaction of the anion of sodium 2-(1,3-benzothiazolyl)ethanonitrile with alpha,2-dibromo-5-nitrotoluene. Its structure features a benzothiazole fragment and a bromo- and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f630dcb6f900c5209d5e0800a614c746
https://pubmed.ncbi.nlm.nih.gov/9208461
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