Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Wieslawa Olszewska"'
Autor:
Devika Sawant, Peter J. M. Openshaw, Corinna Schnoeller, Wieslawa Olszewska, Dominique Raze, Camille Locht, Xavier Le Roux
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 189:194-202
We attenuated virulent Bordetella pertussis by genetically eliminating or detoxifying three major toxins. This strain, named BPZE1, is being developed as a possible live nasal vaccine for the prevention of whooping cough. It is immunogenic and safe w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36d8bc5db55724bb5d031d530f5f0fe7
https://doi.org/10.1164/rccm.201307-1227oc
https://doi.org/10.1164/rccm.201307-1227oc
Autor:
Rebecca Helson, John S. Tregoning, Peter J. M. Openshaw, Amin E. Moghaddam, Wieslawa Olszewska, Quentin J. Sattentau, Belinda Wang
Heat, oxidation and exposure to aldehydes create reactive carbonyl groups on proteins, targeting antigens to scavenger receptors. Formaldehyde is widely used in making vaccines, but has been associated with atypical enhanced disease during subsequent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8251277bae2f4f91b8545e29cf84a46b
https://doi.org/10.1038/nm1456
https://doi.org/10.1038/nm1456
Autor:
D Sawant, Dirk Roymans, R. Verloes, Koen Andries, P Sowinski, B Wang, Anil Koul, Marc Vanstockem, B Van Kerckhove, D Nauwelaers, Marie-Claude Rouan, Peter J. M. Openshaw, F Van Velsen, M De Meulder, P Van Remoortere, C Schnoeller, Wieslawa Olszewska, G Ispas, Jean-François Bonfanti, T Van de Casteele
Publikováno v:
European Respiratory Journal. 38:401-408
Respiratory syncytial virus (RSV) causes bronchiolitis in young children and common colds in adults. There is no licensed vaccine, and prophylactic treatment with palivizumab is very expensive and limited to high-risk infants. Ribavirin is used as an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86870442d480a236e604b1db14574811
https://doi.org/10.1183/09031936.00005610
https://doi.org/10.1183/09031936.00005610
Publikováno v:
Expert Opinion on Emerging Drugs. 14:207-217
Although respiratory syncytial virus (RSV) was discovered > 40 years ago, treatment remains largely supportive. There are no safe and effective vaccines or specific treatments other than prophylaxis with passive antibody therapy (palivizumab). Howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::339f05659206c417e4c957d416e95f19
https://doi.org/10.1517/14728210902946399
https://doi.org/10.1517/14728210902946399
Autor:
Jan zur Megede, Manmohan Singh, José A. Melero, Derek T. O'Hagan, Rebecca Helson, Wieslawa Olszewska, Peter J. M. Openshaw
Publikováno v:
Vaccine. 26:753-761
Priming with the major surface glycoprotein G of respiratory syncytial virus (RSV) expressed by recombinant vaccinia leads to strong Th2 responses and lung eosinophilia during viral challenge. We now show that DNA vaccination in BALB/c mice with plas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7045150f76808622c2e13bc6ccdc18c
https://doi.org/10.1016/j.vaccine.2007.12.006
https://doi.org/10.1016/j.vaccine.2007.12.006
Autor:
Michael W. Steward, Wieslawa Olszewska
Publikováno v:
Virology. 310(1):183-189
Two nonrelated viruses, cowpea mosaic virus (wtCPMV) and measles virus (MV), were found to induce cross-reactive antibodies. The nature of this cross-reactivity was studied and results are presented here demonstrating that antiserum raised against wt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bbfda96fc681e9b3c368418c6cb9e22
Publikováno v:
Vaccine. 20:S27-S31
Inducing a strong immune response is an essential aim of vaccination. Although immune responses to virus infections are usually protective, they can also be harmful. The best-documented examples of an immune response increasing disease severity are w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5155135d512aaec65f59593eeb982908
https://doi.org/10.1016/s0264-410x(01)00301-2
https://doi.org/10.1016/s0264-410x(01)00301-2
Publikováno v:
Archives of Virology. 146:293-302
In this study the immunogenicity of recombinant nucleoprotein (Np) administered intranasally or intraperitoneally, and its ability to support a systemic protective anti-virus antibody response was examined, in a mouse model of measles virus (MV)-indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b3cb5d3ac77073586758e32d4d6d72b
https://doi.org/10.1007/s007050170176
https://doi.org/10.1007/s007050170176
Autor:
Jean‐François Bonfanti, Dirk Roymans, Tom Valerius Josepha Gevers, Frans van Velsen, Gabriela Ispas, Wieslawa Olszewska
Publikováno v:
Antiviral Drugs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87ea76dc99a876d30cfd9c97fe3934f8
https://doi.org/10.1002/9780470929353.ch24
https://doi.org/10.1002/9780470929353.ch24
Autor:
Peter J. M. Openshaw, Allan Randrup Thomsen, Anette Stryhn, Wieslawa Olszewska, Christina Bartholdy
Publikováno v:
The Journal of general virology. 85(Pt 10)
A CD8+ T-cell memory response to respiratory syncytial virus (RSV) was generated by using a DNA vaccine construct encoding the dominant Kd-restricted epitope from the viral transcription anti-terminator protein M2 (M282–90), linked covalently to hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7487dcd2f3195067eb50d2148e4032e
https://pubmed.ncbi.nlm.nih.gov/15448365
https://pubmed.ncbi.nlm.nih.gov/15448365