Downregulation of IL-6-induced STAT3 tyrosine phosphorylation by TGF-beta 1 is mediated by caspase-dependent and -independent processes

Autor: Wierenga, ATJ, Schuringa, JJ, Eggen, BJL, Kruijer, W, Vellenga, E

Publikováno v: Leukemia, 16(4), 675-682. Nature Publishing Group

To explore the possible cross-talk between the IL-6 and TGF-beta1 pathways in AML blast cells, the effect of TGF-beta1 pretreatment on IL-6-induced STAT3 tyrosine phosphorylation was studied. A reduction of STAT3 tyrosine phosphorylation after TGF-be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::8d6fe5ec3f1a571565943ee9057ba073
https://research.rug.nl/en/publications/96d1bc86-4e7b-4473-9a11-6e908ec40163

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Hereditary Alpha Tryptasemia: Validation of a Single-Well Multiplex Digital Droplet PCR Assay in a Cohort of Symptomatic Patients.

Autor: Alheraky A; Department of Laboratory Medicine, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Wierenga ATJ; Department of Laboratory Medicine, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.; Department of Hematology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Simpelaar A; Department of Laboratory Medicine, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Hesp LB; Department of Laboratory Medicine, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Minovic I; Department of Laboratory Medicine, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Bagheri N; Department of Laboratory Medicine, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Roozendaal C; Department of Laboratory Medicine, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Span LFR; Department of Hematology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Oude Elberink HNG; Department of Allergology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.; Groningen Research Institute for Asthma and COPD (GRIAC), University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Kema IP; Department of Laboratory Medicine, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Mulder AB; Department of Laboratory Medicine, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.

Publikováno v: Clinical chemistry [Clin Chem] 2024 Feb 07; Vol. 70 (2), pp. 425-433.