Hydroxycitric acid delays intestinal glucose absorption in rats

Autor: Wielinga, PY, Wachters-Hagedoorn, RE, Bouter, B, van Dijk, TH, Stellaard, F, Nieuwenhuizen, AG, Verkade, HJ, Scheurink, AJW, Nieuwenhuizen, Arie G.

Publikováno v: American Journal of Physiology-Gastrointestinal and Liver Physiology, 288(6), G1144-1149. American Physiological Society
American Journal of Physiology-Gastrointestinal and Liver Physiology, 288(6), G1144-G1149. AMER PHYSIOLOGICAL SOC

In this study, we investigated in rats if hydroxycitric acid (HCA) reduces the postprandial glucose response by affecting gastric emptying or intestinal glucose absorption. We compared the effect of regulator HCA (310 mg/kg) and vehicle (control) on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1f56be62a10d1b22f4726753a970155
https://cris.maastrichtuniversity.nl/en/publications/f4620eb4-98a4-40aa-80cb-4e5ff77fc72d

Lipid ratios representing SCD1, FADS1, and FADS2 activities as candidate biomarkers of early growth and adiposity.

Autor: Olga L; Department of Paediatrics, University of Cambridge, Cambridge, UK., van Diepen JA; Mead Johnson Pediatric Nutrition Institute, Nijmegen, the Netherlands., Bobeldijk-Pastorova I; Department of Metabolic Health Research, The Netherlands Organization for Applied Scientific Research (TNO), Leiden, The Netherlands., Gross G; Mead Johnson Pediatric Nutrition Institute, Nijmegen, the Netherlands., Prentice PM; Department of Paediatrics, University of Cambridge, Cambridge, UK., Snowden SG; Core Metabolomics and Lipidomics Laboratory, Metabolic Research Laboratories, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK., Furse S; Core Metabolomics and Lipidomics Laboratory, Metabolic Research Laboratories, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK., Kooistra T; Department of Metabolic Health Research, The Netherlands Organization for Applied Scientific Research (TNO), Leiden, The Netherlands., Hughes IA; Department of Paediatrics, University of Cambridge, Cambridge, UK., Schoemaker MH; Mead Johnson Pediatric Nutrition Institute, Nijmegen, the Netherlands., van Tol EAF; Mead Johnson Pediatric Nutrition Institute, Nijmegen, the Netherlands; Department of Metabolic Health Research, The Netherlands Organization for Applied Scientific Research (TNO), Leiden, The Netherlands., van Duyvenvoorde W; Department of Metabolic Health Research, The Netherlands Organization for Applied Scientific Research (TNO), Leiden, The Netherlands., Wielinga PY; Department of Metabolic Health Research, The Netherlands Organization for Applied Scientific Research (TNO), Leiden, The Netherlands., Ong KK; Department of Paediatrics, University of Cambridge, Cambridge, UK; MRC Epidemiology Unit, Wellcome Trust-MRC Institute of Metabolic Science, NIHR Cambridge Comprehensive Biomedical Research Centre, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK; Wellcome-MRC Institute of Metabolic Science-Metabolic Research Laboratories' or (IMS-MRL), University of Cambridge, Cambridge, UK., Dunger DB; Department of Paediatrics, University of Cambridge, Cambridge, UK; Wellcome-MRC Institute of Metabolic Science-Metabolic Research Laboratories' or (IMS-MRL), University of Cambridge, Cambridge, UK., Kleemann R; Department of Metabolic Health Research, The Netherlands Organization for Applied Scientific Research (TNO), Leiden, The Netherlands; Department of Vascular Surgery, Leiden University Medical Center, Leiden, The Netherlands., Koulman A; Core Metabolomics and Lipidomics Laboratory, Metabolic Research Laboratories, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK; MRC Epidemiology Unit, Wellcome Trust-MRC Institute of Metabolic Science, NIHR Cambridge Comprehensive Biomedical Research Centre, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK; Wellcome-MRC Institute of Metabolic Science-Metabolic Research Laboratories' or (IMS-MRL), University of Cambridge, Cambridge, UK. Electronic address: ak675@medschl.cam.ac.uk.

Publikováno v: EBioMedicine [EBioMedicine] 2021 Jan; Vol. 63, pp. 103198. Date of Electronic Publication: 2021 Jan 07.

Obeticholic Acid Modulates Serum Metabolites and Gene Signatures Characteristic of Human NASH and Attenuates Inflammation and Fibrosis Progression in Ldlr-/-.Leiden Mice.

Autor: Morrison MC; Department of Metabolic Health Research Netherlands Organization for Applied Scientific Research Leiden The Netherlands., Verschuren L; Department of Microbiology and Systems Biology Netherlands Organisation for Applied Scientific Research Zeist The Netherlands., Salic K; Department of Metabolic Health Research Netherlands Organization for Applied Scientific Research Leiden The Netherlands., Verheij J; Department of Pathology Amsterdam Medical Center Amsterdam The Netherlands., Menke A; Department of Pathology Triskelion B.V. Zeist The Netherlands., Wielinga PY; Department of Metabolic Health Research Netherlands Organization for Applied Scientific Research Leiden The Netherlands., Iruarrizaga-Lejarreta M; OWL Metabolomics Derio Spain., Gole L; Computational BioImage Analysis Unit, Agency of Science, Technology and Research (ASTAR), Institute of Molecular and Cell Biology Singapore., Yu WM; Computational BioImage Analysis Unit, Agency of Science, Technology and Research (ASTAR), Institute of Molecular and Cell Biology Singapore., Turner S; Kinemed Inc. Emeryville CA., Caspers MPM; Department of Microbiology and Systems Biology Netherlands Organisation for Applied Scientific Research Zeist The Netherlands., Martínez-Arranz I; OWL Metabolomics Derio Spain., Pieterman E; Department of Metabolic Health Research Netherlands Organization for Applied Scientific Research Leiden The Netherlands., Stoop R; Department of Metabolic Health Research Netherlands Organization for Applied Scientific Research Leiden The Netherlands., van Koppen A; Department of Metabolic Health Research Netherlands Organization for Applied Scientific Research Leiden The Netherlands., van den Hoek AM; Department of Metabolic Health Research Netherlands Organization for Applied Scientific Research Leiden The Netherlands., Mato JM; CIC bioGUNE, CIBERehd Derio Spain., Hanemaaijer R; Department of Metabolic Health Research Netherlands Organization for Applied Scientific Research Leiden The Netherlands., Alonso C; OWL Metabolomics Derio Spain., Kleemann R; Department of Metabolic Health Research Netherlands Organization for Applied Scientific Research Leiden The Netherlands.

Publikováno v: Hepatology communications [Hepatol Commun] 2018 Oct 29; Vol. 2 (12), pp. 1513-1532. Date of Electronic Publication: 2018 Oct 29 (Print Publication: 2018).

Protective effect of rosiglitazone on kidney function in high-fat challenged human-CRP transgenic mice: a possible role for adiponectin and miR-21?

Autor: Morrison MC; Department of Metabolic Health Research, Netherlands Organization for Applied Scientific Research (TNO), Zernikedreef 9, 2333, CK, Leiden, The Netherlands. martine.morrison@tno.nl., Yakala GK; Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Hanzeplein 1 (EA11), 9713, GZ, Groningen, The Netherlands., Liang W; Department of Metabolic Health Research, Netherlands Organization for Applied Scientific Research (TNO), Zernikedreef 9, 2333, CK, Leiden, The Netherlands., Wielinga PY; Department of Metabolic Health Research, Netherlands Organization for Applied Scientific Research (TNO), Zernikedreef 9, 2333, CK, Leiden, The Netherlands., Salic K; Department of Metabolic Health Research, Netherlands Organization for Applied Scientific Research (TNO), Zernikedreef 9, 2333, CK, Leiden, The Netherlands., van Koppen A; Department of Metabolic Health Research, Netherlands Organization for Applied Scientific Research (TNO), Zernikedreef 9, 2333, CK, Leiden, The Netherlands., Tomar T; Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Hanzeplein 1 (EA11), 9713, GZ, Groningen, The Netherlands., Kleemann R; Department of Metabolic Health Research, Netherlands Organization for Applied Scientific Research (TNO), Zernikedreef 9, 2333, CK, Leiden, The Netherlands., Heeringa P; Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Hanzeplein 1 (EA11), 9713, GZ, Groningen, The Netherlands., Kooistra T; Department of Metabolic Health Research, Netherlands Organization for Applied Scientific Research (TNO), Zernikedreef 9, 2333, CK, Leiden, The Netherlands.

Publikováno v: Scientific reports [Sci Rep] 2017 Jun 06; Vol. 7 (1), pp. 2915. Date of Electronic Publication: 2017 Jun 06.

CAT-2003: A novel sterol regulatory element-binding protein inhibitor that reduces steatohepatitis, plasma lipids, and atherosclerosis in apolipoprotein E*3-Leiden mice.

Autor: Zimmer M; Catabasis Pharmaceuticals Cambridge MA., Bista P; Catabasis Pharmaceuticals Cambridge MA., Benson EL; Catabasis Pharmaceuticals Cambridge MA., Lee DY; Catabasis Pharmaceuticals Cambridge MA., Liu F; Catabasis Pharmaceuticals Cambridge MA., Picarella D; Catabasis Pharmaceuticals Cambridge MA., Vega RB; Catabasis Pharmaceuticals Cambridge MA., Vu CB; Catabasis Pharmaceuticals Cambridge MA., Yeager M; Catabasis Pharmaceuticals Cambridge MA., Ding M; Department of Molecular Genetics University of Texas Southwestern Medical Center at Dallas Dallas TX., Liang G; Department of Molecular Genetics University of Texas Southwestern Medical Center at Dallas Dallas TX., Horton JD; Department of Molecular Genetics University of Texas Southwestern Medical Center at Dallas Dallas TX.; Department of Internal Medicine University of Texas Southwestern Medical Center at Dallas Dallas TX.; Center for Human Nutrition University of Texas Southwestern Medical Center at Dallas Dallas TX., Kleemann R; Netherlands Organization for Applied Scientific Research, Department of Metabolic Health Research Leiden the Netherlands., Kooistra T; Netherlands Organization for Applied Scientific Research, Department of Metabolic Health Research Leiden the Netherlands., Morrison MC; Netherlands Organization for Applied Scientific Research, Department of Metabolic Health Research Leiden the Netherlands., Wielinga PY; Netherlands Organization for Applied Scientific Research, Department of Metabolic Health Research Leiden the Netherlands., Milne JC; Catabasis Pharmaceuticals Cambridge MA., Jirousek MR; Catabasis Pharmaceuticals Cambridge MA., Nichols AJ; Catabasis Pharmaceuticals Cambridge MA.

Publikováno v: Hepatology communications [Hepatol Commun] 2017 May 12; Vol. 1 (4), pp. 311-325. Date of Electronic Publication: 2017 May 12 (Print Publication: 2017).