Zobrazeno 1 - 10 of 27 pro vyhledávání: '"Wieke W Kremer"'
1
Akademický článek
Role of FAM19A4/miR124-2 methylation analysis in predicting regression or non-regression of CIN2/3 lesions: a protocol of an observational longitudinal cohort study
Autor: Wieke W Kremer, Johannes Berkhof, Maaike CG Bleeker, Daniëlle AM Heideman, Nienke E van Trommel, Marchien W van Baal, Harold R Verhoeve, Chris JLM Meijer, Gemma G Kenter
Publikováno v: BMJ Open, Vol 9, Iss 7 (2019)
Introduction The clinical course of high-grade cervical intraepithelial neoplasia (CIN2/3) is characterised by a high spontaneous regression rate. Histological assessment is unable to differentiate between CIN2/3 lesions likely to regress and those l
Externí odkaz: https://doaj.org/article/d614a9aafa4c4986ab14deced4800b7a
Zobrazit plný text záznamu
2
Post-treatment monitoring by ASCL1/LHX8 methylation analysis in women with HIV treated for cervical intraepithelial neoplasia grade 2/3
Autor: Frederique J. Vink, Renske D.M. Steenbergen, Wieke W. Kremer, Birgit I. Lissenberg-Witte, Daniëlle A.M. Heideman, Maaike C.G. Bleeker, Marjolein van Zummeren, Erika Breytenbach, Cathy Visser, Azwidowi Lukhwareni, Chris J.L.M. Meijer, Greta Dreyer
Publikováno v: AIDS (London, England), 36(7), 953-961. Lippincott Williams and Wilkins
Vink, F J, Steenbergen, R D M, Kremer, W W, Lissenberg-Witte, B I, Heideman, D A M, Bleeker, M C G, van Zummeren, M, Breytenbach, E, Visser, C, Lukhwareni, A, Meijer, C J L M & Dreyer, G 2022, ' Post-treatment monitoring by ASCL1/LHX8 methylation analysis in women with HIV treated for cervical intraepithelial neoplasia grade 2/3 ', AIDS (London, England), vol. 36, no. 7, pp. 953-961 . https://doi.org/10.1097/QAD.0000000000003197
Objective:Women with HIV (WWH) have an increased risk to develop recurrent cervical intraepithelial neoplasia grade 2/3 (rCIN2/3) after treatment compared with HIV-negative women. Therefore, appropriate posttreatment monitoring of WWH is important. T
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0057fcc248c3853650a2db213c8cb807
https://research.vumc.nl/en/publications/368d8035-bcf9-4d12-b4f7-b5fda9373928
Zobrazit plný text záznamu
3
Clinical Regression of High-Grade Cervical Intraepithelial Neoplasia Is Associated With Absence of
Autor: Wieke W, Kremer, Stèfanie, Dick, Daniëlle A M, Heideman, Renske D M, Steenbergen, Maaike C G, Bleeker, Harold R, Verhoeve, W Marchien, van Baal, Nienke, van Trommel, Gemma G, Kenter, Chris J L M, Meijer, Johannes, Berkhof
Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 40(26)
Cervical screening can prevent cancer by detection and treatment of cervical intraepithelial neoplasia grade 2 or 3 (CIN2/3). Screening also results in considerable overtreatment because many CIN2/3 lesions show spontaneous regression when left untre
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cc0c639391af0895c580c3878d05070d
https://pubmed.ncbi.nlm.nih.gov/35594490
Zobrazit plný text záznamu
4
Clinical Regression of High-Grade Cervical Intraepithelial Neoplasia Is Associated With Absence of FAM19A4/miR124-2 DNA Methylation (CONCERVE Study)
Autor: Wieke W. Kremer, Stèfanie Dick, Daniëlle A.M. Heideman, Renske D.M. Steenbergen, Maaike C.G. Bleeker, Harold R. Verhoeve, W. Marchien van Baal, Nienke van Trommel, Gemma G. Kenter, Chris J.L.M. Meijer, Johannes Berkhof
Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. American Society of Clinical Oncology
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 189:e2102433. American Society of Clinical Oncology
Kremer, W W, Dick, S, Heideman, D A M, Steenbergen, R D M, Bleeker, M C G, Verhoeve, H R, van Baal, W M, van Trommel, N, Kenter, G G, Meijer, C J L M & Berkhof, J 2022, ' Clinical Regression of High-Grade Cervical Intraepithelial Neoplasia Is Associated With Absence of FAM19A4/miR124-2 DNA Methylation (CONCERVE Study) ', Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol. 189, e2102433, pp. JCO2102433 . https://doi.org/10.1200/JCO.21.02433
Journal of Clinical Oncology, 189:e2102433. American Society of Clinical Oncology
PURPOSE Cervical screening can prevent cancer by detection and treatment of cervical intraepithelial neoplasia grade 2 or 3 (CIN2/3). Screening also results in considerable overtreatment because many CIN2/3 lesions show spontaneous regression when le
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::effda8b855240bfdaeee96e37c9439c4
https://research.vumc.nl/en/publications/65040442-b625-4746-92f1-e159dc3c302a
Zobrazit plný text záznamu
5
Akademický článek
HPV16-Related Cervical Cancers and Precancers Have Increased Levels of Host Cell DNA Methylation in Women Living with HIV
Autor: Wieke W. Kremer, Marjolein van Zummeren, Daniëlle A. M. Heideman, Birgit I. Lissenberg-Witte, Peter J. F. Snijders, Renske D. M. Steenbergen, Greta Dreyer, Chris J. L. M. Meijer
Publikováno v: International Journal of Molecular Sciences, Vol 19, Iss 11, p 3297 (2018)
Data on human papillomavirus (HPV) type-specific cervical cancer risk in women living with human immunodeficiency virus (WLHIV) are needed to understand HPV–HIV interaction and to inform prevention programs for this population. We assessed high-ris
Externí odkaz: https://doaj.org/article/25eb3ea2782048a8a3e24d0beef3f9c7
Zobrazit plný text záznamu
6
The use of host cell DNA methylation analysis in the detection and management of women with advanced cervical intraepithelial neoplasia: A review
Autor: Christophorus Joannes Lambertus Maria Meijer, Renske D.M. Steenbergen, Wieke W. Kremer, Daniëlle A M Heideman, Gemma G. Kenter
Publikováno v: Kremer, W W, Steenbergen, R D M, Heideman, D A M, Kenter, G G & Meijer, C J L M 2021, ' The use of host cell DNA methylation analysis in the detection and management of women with advanced cervical intraepithelial neoplasia: A review ', Obstetrical and Gynecological Survey, vol. 76, no. 5, pp. 273-274 . https://doi.org/10.1097/ogx.0000000000000922
Bjog
Kremer, W W, Steenbergen, R, Heideman, D, Kenter, G G & Meijer, C 2021, ' The use of host cell DNA methylation analysis in the detection and management of women with advanced cervical intraepithelial neoplasia : a review ', BJOG: An International Journal of Obstetrics & Gynaecology, vol. 128, no. 3, pp. 504-514 . https://doi.org/10.1111/1471-0528.16395
This paper briefly reviews the role of hypermethylation of host cell genes in cervical carcinogenesis and discusses potential clinical applications of methylation analysis in the management of high‐risk HPV (hrHPV) ‐positive women. We argue that
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d99bd4b8f41b0dbc43c8cfb10bf51ccb
https://research.vumc.nl/en/publications/69cc2228-1f62-4f08-8e1e-b0f309389267
Zobrazit plný text záznamu
7
Characterization of cervical biopsies of women with HIV and HPV co-infection using p16ink4a, ki-67 and HPV E4 immunohistochemistry and DNA methylation
Autor: Wieke W. Kremer, Greta Dreyer, Frederique J Vink, Marjolein van Zummeren, Chris J.L.M. Meijer, Lawrence Rozendaal, Maaike C G Bleeker, John Doorbar
Publikováno v: Modern Pathology, 33(10), 1968-1978. Nature Publishing Group
Kremer, W W, Vink, F J, van Zummeren, M, Dreyer, G, Rozendaal, L, Doorbar, J, Bleeker, M C G & Meijer, C J L M 2020, ' Characterization of cervical biopsies of women with HIV and HPV co-infection using p16ink4a, ki-67 and HPV E4 immunohistochemistry and DNA methylation ', Modern Pathology, vol. 33, no. 10, pp. 1968-1978 . https://doi.org/10.1038/s41379-020-0528-x, https://doi.org/10.1038/s41379-020-0528-x
This study aims to characterize cervical intraepithelial neoplasia (CIN) in women living with HIV using biomarkers. Immunohistochemical (IHC) staining for human papillomavirus (HPV) E4 protein indicates CIN with productive HPV infection, whereas Ki-6
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8553f3390b268cc0c63f5c1b050c6f58
https://research.vumc.nl/en/publications/1043b088-cbce-4ff2-890f-6dd65d0064d9
Zobrazit plný text záznamu
8
Three-tiered score for Ki-67 and p16ink4a improves accuracy and reproducibility of grading CIN lesions
Autor: Renske D.M. Steenbergen, Annemiek Leeman, Peter J.F. Snijders, Marjolein van Zummeren, Maaike C G Bleeker, Wieke W. Kremer, Chris J.L.M. Meijer, Johannes Berkhof, Daniëlle A.M. Heideman, Miekel M. van de Sandt, David G. Jenkins, Wim Quint
Publikováno v: Journal of Clinical Pathology
AimsTo investigate the accuracy and reproducibility of a scoring system for cervical intraepithelial neoplasia (CIN1–3) based on immunohistochemical (IHC) biomarkers Ki-67 and p16ink4a.Methods115 cervical tissue specimens were reviewed by three exp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86b1119ed680d75e8a705e6d0f7ba20e
http://europepmc.org/articles/PMC6225805
Zobrazit plný text záznamu
9
The use of molecular markers for cervical screening of women living with HIV in South Africa
Autor: Renske D.M. Steenbergen, Wieke W. Kremer, Erika Breytenbach, Marjolein van Zummeren, Chris J.L.M. Meijer, Greta Dreyer, Karin Louise Richter
Publikováno v: AIDS, 33(13), 2035-2042. Lippincott Williams and Wilkins
Kremer, W W, van Zummeren, M, Breytenbach, E, Richter, K L, Steenbergen, R D M, Meijer, C J L M & Dreyer, G 2019, ' The use of molecular markers for cervical screening of women living with HIV in South Africa ', AIDS, vol. 33, no. 13, pp. 2035-2042 . https://doi.org/10.1097/QAD.0000000000002325
AIDS (London, England)
Supplemental Digital Content is available in the text
Objective: To determine the performance of molecular screening strategies for detection of cervical intraepithelial neoplasia grade 3 or worse (CIN3+) in comparison with cytology screening in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f61e0acfa0e09e75aa463bc0f1e2a070
https://research.vumc.nl/en/publications/8c624ddf-3126-498a-a3ad-81c4aa106a7c
Zobrazit plný text záznamu
10
Long-term CIN3+ risk of HPV positive women after triage with FAM19A4/miR124-2 methylation analysis
Autor: Wieke W. Kremer, Renske D.M. Steenbergen, Daniëlle A M Heideman, Birgit I. Lissenberg-Witte, Stèfanie Dick, Chris J.L.M. Meijer, Lise M.A. De Strooper, Johannes Berkhof
Publikováno v: Dick, S, Kremer, W W, De Strooper, L M A, Lissenberg-Witte, B I, Steenbergen, R D M, Meijer, C J L M, Berkhof, J & Heideman, D A M 2019, ' Long-term CIN3+ risk of HPV positive women after triage with FAM19A4/miR124-2 methylation analysis ', Gynecologic Oncology, vol. 154, no. 2, pp. 368-373 . https://doi.org/10.1016/j.ygyno.2019.06.002
Gynecologic Oncology, 154(2), 368-373. Academic Press Inc.
OBJECTIVE: This study evaluates the long-term risk for cervical intraepithelial neoplasia grade 3 or worse (CIN3+) among HPV positive women triaged with FAM19A4/miR124-2 methylation analysis.METHODS: In a post hoc analysis, data on FAM19A4/miR124-2 m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::023e78585c88904f52bc963b5b83d4c4
https://research.vumc.nl/en/publications/7bcd3602-1b96-4699-a92f-a904edb47ccc
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje