Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Wieke M. van Oostveen"'
Autor:
Tamara A. M. Mocking, Wieke M. van Oostveen, Jacobus P. D. van Veldhoven, Hugo Minnee, Cynthia M. Fehres, Charles E. Whitehurst, Adriaan P. IJzerman, Laura H. Heitman
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
The prostaglandin transporter (PGT, SLCO2A1) mediates transport of prostanoids (a.o. prostaglandin E2 (PGE2)) into cells and thereby promotes their degradation. Overexpression of PGT leads to low extracellular PGE2 levels and has been linked to impai
Externí odkaz:
https://doaj.org/article/e0cc08e3ad25430fb31c87cdf54e7ca2
Autor:
Hubert J. Sijben, Wieke M. van Oostveen, Peter B. R. Hartog, Laura Stucchi, Andrea Rossignoli, Giovanna Maresca, Lia Scarabottolo, Adriaan P. IJzerman, Laura H. Heitman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract The human norepinephrine transporter (NET) is an established drug target for a wide range of psychiatric disorders. Conventional methods that are used to functionally characterize NET inhibitors are based on the use of radiolabeled or fluore
Externí odkaz:
https://doaj.org/article/f31bd47fc7a84a55966bc22ad396c6be
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4, p 2110 (2021)
Background. Alzheimer’s disease (AD) is a progressive neurodegenerative disorder affecting many individuals worldwide with no effective treatment to date. AD is characterized by the formation of senile plaques and neurofibrillary tangles, followed
Externí odkaz:
https://doaj.org/article/960e265a7fc34a35a30025f2548238c1
Autor:
Andrea Rossignoli, Wieke M. van Oostveen, Laura Stucchi, Hubert J. Sijben, Lia Scarabottolo, Adriaan P. IJzerman, Giovanna Maresca, Laura H. Heitman, Peter B. R. Hartog
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports, 11. Springer Science and Business Media LLC
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports, 11. Springer Science and Business Media LLC
The human norepinephrine transporter (NET) is an established drug target for a wide range of psychiatric disorders. Conventional methods that are used to functionally characterize NET inhibitors are based on the use of radiolabeled or fluorescent sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a16662e2c607a773ad0de4e14975ea98
https://doi.org/10.1038/s41598-021-91700-7
https://doi.org/10.1038/s41598-021-91700-7
