Zobrazeno 1 - 10 of 540 pro vyhledávání: '"Wiek H Van Gilst"'
1
Akademický článek
A Kinase Interacting Protein 1 (AKIP1) promotes cardiomyocyte elongation and physiological cardiac remodelling
Autor: Kirsten T. Nijholt, Pablo I. Sánchez-Aguilera, Harmen G. Booij, Silke U. Oberdorf-Maass, Martin M. Dokter, Anouk H. G. Wolters, Ben N. G. Giepmans, Wiek H. van Gilst, Joan H. Brown, Rudolf A. de Boer, Herman H. W. Silljé, B. Daan Westenbrink
Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract A Kinase Interacting Protein 1 (AKIP1) is a signalling adaptor that promotes physiological hypertrophy in vitro. The purpose of this study is to determine if AKIP1 promotes physiological cardiomyocyte hypertrophy in vivo. Therefore, adult ma
Externí odkaz: https://doaj.org/article/ed562cee66ed427ca8cecb89312bca87
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2
Akademický článek
Fibroblast Growth Factor 23 and Risk of New Onset Heart Failure With Preserved or Reduced Ejection Fraction: The PREVEND Study
Autor: S. Heleen Binnenmars, Georgette E. Hoogslag, Stanley M. H. Yeung, Frank P. Brouwers, Stephan J. L. Bakker, Wiek H. van Gilst, Ron T. Gansevoort, Gerjan Navis, Adriaan A. Voors, Martin H. de Borst
Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 15 (2022)
Background The role of fibroblast growth factor 23 (FGF23) in the development of new‐onset heart failure (HF) with reduced (HFrEF) or preserved ejection fraction (HFpEF) in the general population is unknown. Therefore, we set out to investigate ass
Externí odkaz: https://doaj.org/article/82473be853ec4938a5b5c823404e5ba4
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3
Galectin-3 and Blood Group: Binding Properties, Effects on Plasma Levels, and Consequences for Prognostic Performance
Autor: Carolin Pozder, Elles M. Screever, A. Rogier van der Velde, Herman H. Silljé, Janne Suwijn, Saskia de Rond, Marcus E. Kleber, Graciela Delgado, Jan Jacob Schuringa, Wiek H. van Gilst, Wouter C. Meijers, Winfried März, Rudolf A. de Boer
Publikováno v: International Journal of Molecular Sciences, 24(5):4415. MDPI AG
International Journal of Molecular Sciences
Volume 24
Issue 5
Pages: 4415
International Journal of Molecular Sciences, 24(5):4415. Multidisciplinary Digital Publishing Institute (MDPI)
Previous studies have reported an association between ABO type blood group and cardiovascular (CV) events and outcomes. The precise mechanisms underpinning this striking observation remain unknown, although differences in von Willebrand factor (VWF)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e889e728c734f0f670ad1bd4da0d9437
https://research.rug.nl/en/publications/2301f162-8288-41ab-9449-dc30ba22ca23
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4
Risk, Clinical Course, and Outcome of Ischemic Stroke in Patients Hospitalized With COVID-19
Autor: Wouter M. Sluis, Marijke Linschoten, Julie E. Buijs, J. Matthijs Biesbroek, Heleen M. den Hertog, Tessa Ribbers, Dennis J. Nieuwkamp, Reinier C. van Houwelingen, Andreas Dias, Ingeborg W.M. van Uden, Joost P. Kerklaan, H. Paul Bienfait, Sarah E. Vermeer, Sonja W. de Jong, Mariam Ali, Marieke J.H. Wermer, Marieke T. de Graaf, Paul J.A.M. Brouwers, Folkert W. Asselbergs, L. Jaap Kappelle, H. Bart van der Worp, Annemijn M. Algra, Richard C.J.M. Donders, D. Martijn O. Pruissen, Aaf F.M. Kuijper, Clara E.E. van Ofwegen-Hanekamp, Rik S. Hermanides, Hortence E. Haerkens-Arends, Rutger L. Anthonio, Mireille E. Emans, René A. Tio, Jur M. ten Berg, Björn E. Groenemeijer, Ron Pisters, P. Marc van der Zee, Hans-Marc J. Siebelink, Derk O. Verschure, Matthijs F.L. Meijs, Astrid Schut, Robert G. Tieleman, Wanda Hermans-van Ast, Jeroen Schaap, Lucia S. Jewbali, Peter C. Smits, Pim van der Harst, Maarten van Smeden, Wiek H. van Gilst
Publikováno v: Stroke, 52(12), 3978-3986. LIPPINCOTT WILLIAMS & WILKINS
Stroke, 52(12), 3978-3986. Lippincott Williams and Wilkins
Stroke, 52(12), 3978-3986. Lippincott Williams & Wilkins
Background and Purpose: The frequency of ischemic stroke in patients with coronavirus disease 2019 (COVID-19) varies in the current literature, and risk factors are unknown. We assessed the incidence, risk factors, and outcomes of acute ischemic stro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bdef6d527a91e1daeac6ec5170ab0d2
https://doi.org/10.1161/strokeaha.121.034787
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6
Akademický článek
Cardiac LXRα protects against pathological cardiac hypertrophy and dysfunction by enhancing glucose uptake and utilization
Autor: Megan V Cannon, Herman HW Silljé, Jürgen WA Sijbesma, Inge Vreeswijk‐Baudoin, Jolita Ciapaite, Bart van der Sluis, Jan van Deursen, Gustavo JJ Silva, Leon J de Windt, Jan‐Åke Gustafsson, Pim van der Harst, Wiek H van Gilst, Rudolf A de Boer
Publikováno v: EMBO Molecular Medicine, Vol 7, Iss 9, Pp 1229-1243 (2015)
Abstract Pathological cardiac hypertrophy is characterized by a shift in metabolic substrate utilization from fatty acids to glucose, but the molecular events underlying the metabolic remodeling remain poorly understood. Here, we investigated the rol
Externí odkaz: https://doaj.org/article/a60b17b5ab81414fab6747461a6c56fa
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7
The erythropoietin receptor expressed in skeletal muscle is essential for mitochondrial biogenesis and physiological exercise
Autor: Alexander H. Maass, Kirsten T Nijholt, Willem P. T. Ruifrok, B. Daan Westenbrink, Belend Mahmoud, Herman H W Silljé, Salva R. Yurista, Rudolf A. de Boer, Dirk J. van Veldhuisen, Mario G. Pavez-Giani, Wiek H. van Gilst, L. M. G. Meems, Anouk H G Wolters
Publikováno v: Pflugers Archiv
Pflügers Archiv : European Journal of Physiology. SPRINGER
Erythropoietin (EPO) is a haematopoietic hormone that regulates erythropoiesis, but the EPO-receptor (EpoR) is also expressed in non-haematopoietic tissues. Stimulation of the EpoR in cardiac and skeletal muscle provides protection from various forms
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::371e6f2e3e5fb3b86f7a3650108578b2
https://doi.org/10.1007/s00424-021-02577-4
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8
Digital arterial pressure pulse wave analysis and cardiovascular events in the general population
Autor: Arie M. van Roon, Adriaan A. Voors, Douwe J. Mulder, Hendrik T J Bijen, Jens T. Bakker, Maarten A. de Jong, Ron T. Gansevoort, Stephan J. L. Bakker, Martin H. de Borst, Wiek H. van Gilst, Frank P. Brouwers
Publikováno v: Journal of Hypertension, 38(6), 1064-1071. LIPPINCOTT WILLIAMS & WILKINS
Journal of Hypertension
BACKGROUND: Arterial stiffness influences the contour of the digital pressure pulse wave. METHOD: Here, we investigated whether the digital pulse propagation index (DPPI), based on the digital pressure pulse wave, DPPI is associated with cardiovascul
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6a0126746b9276684fee331a1e720b3
https://doi.org/10.1097/hjh.0000000000002390
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9
Pectins from various sources inhibit galectin-3-related cardiac fibrosis
Autor: Pieter Muntendam, Carolin Gehlken, Martin M Dokter, Wiek H. van Gilst, Wouter C. Meijers, Henk A. Schols, Rudolf A. de Boer, A. Rogier van der Velde, Herman H W Silljé
Publikováno v: Current Research in Translational Medicine, 70(1):103321
Current Research in Translational Medicine 70 (2022) 1
Current Research in Translational Medicine, 70(1)
Purpose of the study: A major challenge in cardiology remains in finding a therapy for cardiac fibrosis. Inhibition of galectin-3 with pectins attenuates fibrosis in animal models of heart failure. The purpose of this study is to identify pectins wit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd67b1c6f4f133c4f9fe28bb8786a2d1
https://doi.org/10.1016/j.retram.2021.103321
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10
Age-stratified and blood-pressure-stratified effects of blood-pressure-lowering pharmacotherapy for the prevention of cardiovascular disease and death: an individual participant-level data meta-analysis
Autor: Milad Nazarzadeh, Morris J. Brown, Anthony Rodgers, Henry R. Black, Takao Saruta, Hiromichi Suzuki, Sverre E. Kjeldsen, Barry R. Davis, Anushka Patel, Edmund J. Lewis, John B. Kostis, Stevo Julius, Giuseppe Remuzzi, Jan A. Staessen, Stephan Lueders, Lutgarde Thijs, Ji-Guang Wang, Jan Lanke, Rory Collins, Amanda I Adler, Ray Estacio, Gianpaolo Reboldi, Yoshiki Yui, Yoshihiko Kanno, Michel Lievre, Ajay Gupta, Hiroshi Ogawa, Piero Ruggenenti, Maria H Mehlum, Peter Sleight, Craig S. Anderson, Tsuguya Fukui, Ale Algra, Jamie P. Dwyer, William C. Cushman, MA Pfeffer, Ettore Malacco, Julia B. Lewis, Kenji Ueshima, Peter S. Sever, Lars H Lindholm, Steven E. Nissen, Larry Agodoa, Dexter Canoy, Christopher J. Bulpitt, Robert P Byington, Zeinab Bidel, Richard J McManus, Giancarlo Viberti, N Beckett, Jasper J Brugts, Eivind Berge, Frank P. Brouwers, Jacobus Lubsen, Robert W. Schrier, Johan Sundström, Salim Yusuf, Lindon Wing, Zhen-Yu Zhang, Paul K. Whelton, Colin Baigent, Alberto Zanchetti, Toshio Ogihara, Barry M. Brenner, Jeffrey Cutler, Bruce Neal, Paolo Verdecchia, Dick de Zeeuw, Stephen MacMahon, Takayoshi Ohkubo, Emma Copland, Wiek H. van Gilst, Folkert W. Asselbergs, Neil R Poulter, Kristian Wachtell, Vlado Perkovic, Kazem Rahimi, Christopher M. Reid, Peter M. Rothwell, Seiji Umemoto, Hiromi Rakugi, Koon K. Teo, Kim Fox, Malgorzata Wamil, Masao Ishii, Mark Woodward, Fiona Turnbull, Kizuku Kuramoto, Richard B Devereaux, Christopher R. Palmer, Joachim Schrader, Carl J. Pepine, Robert Fagard, Giuseppe Mancia, Rury R. Holman, Masunori Matsuzaki, Eric Boersma, John Chalmers, Jeannette Majert, Gholamreza Salimi-Khorshidi, Bertram Pitt, Yutaka Imai
Publikováno v: The Lancet, 398(10305), 1053-1064. Elsevier Ltd.
Background The effects of pharmacological blood-pressure-lowering on cardiovascular outcomes in individuals aged 70 years and older, particularly when blood pressure is not substantially increased, is uncertain. We compared the effects of blood-press
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b32b7994875e1d4ad1d2b712dd71cf4f
https://doi.org/10.1016/s0140-6736(21)01921-8
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