Zobrazeno 1 - 10
of 2 156
pro vyhledávání: '"Wieder P"'
The increasing size of screening libraries poses a significant challenge for the development of virtual screening methods for drug discovery, necessitating a re-evaluation of traditional approaches in the era of big data. Although 3D pharmacophore sc
Externí odkaz:
http://arxiv.org/abs/2409.06316
Autor:
Wang, Yuanqing, Takaba, Kenichiro, Chen, Michael S., Wieder, Marcus, Xu, Yuzhi, Zhu, Tong, Zhang, John Z. H., Nagle, Arnav, Yu, Kuang, Wang, Xinyan, Cole, Daniel J., Rackers, Joshua A., Cho, Kyunghyun, Greener, Joe G., Eastman, Peter, Martiniani, Stefano, Tuckerman, Mark E.
A force field as accurate as quantum mechanics (QM) and as fast as molecular mechanics (MM), with which one can simulate a biomolecular system efficiently enough and meaningfully enough to get quantitative insights, is among the most ardent dreams of
Externí odkaz:
http://arxiv.org/abs/2409.01931
Autor:
In-Won Kim, Axel Timmermann, Ji-Eun Kim, Keith B. Rodgers, Sun-Seon Lee, Hanna Lee, William R. Wieder
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Unabated 21st-century climate change will accelerate Arctic-Subarctic permafrost thaw which can intensify microbial degradation of carbon-rich soils, methane emissions, and global warming. The impact of permafrost thaw on future Arctic-Subar
Externí odkaz:
https://doaj.org/article/df95484f4be64fbab045a6b50545e850
Autor:
Ross O’Hagan, MD, Samir Kamat, MD, Shira Wieder, MD, Marcel Perl, MD, Jonathan I. Silverberg, MD, PhD, MPH, Nanette B. Silverberg, MD
Publikováno v:
JAAD International, Vol 16, Iss , Pp 127-129 (2024)
Externí odkaz:
https://doaj.org/article/50f00e523a2a42728cbc2035a0173e99
Autor:
Ross O’Hagan, MD, Shira Wieder, MD, Marcel Perl, MD, Jonathan I. Silverberg, MD, PhD, MPH, Nanette B. Silverberg, MD
Publikováno v:
International Journal of Women's Dermatology, Vol 10, Iss 3, p e177 (2024)
Externí odkaz:
https://doaj.org/article/3eeec976a945469cb129a4a8cd4b9801
We present a new perspective on loss minimization and the recent notion of Omniprediction through the lens of Outcome Indistingusihability. For a collection of losses and hypothesis class, omniprediction requires that a predictor provide a loss-minim
Externí odkaz:
http://arxiv.org/abs/2210.08649
Autor:
Nechama Wieder, Elston N. D’Souza, Alexandra C. Martin-Geary, Frederik H. Lassen, Jonathan Talbot-Martin, Maria Fernandes, Sonia P. Chothani, Owen J. L. Rackham, Sebastian Schafer, Julie L. Aspden, Daniel G. MacArthur, Robert W. Davies, Nicola Whiffin
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-16 (2024)
Abstract Background Untranslated regions (UTRs) are important mediators of post-transcriptional regulation. The length of UTRs and the composition of regulatory elements within them are known to vary substantially across genes, but little is known ab
Externí odkaz:
https://doaj.org/article/419dbeb079c94514871454c4158e40f1
Autor:
Schindler, Frank, Tsirkin, Stepan S., Neupert, Titus, Bernevig, B. Andrei, Wieder, Benjamin J.
Publikováno v:
Nat. Commun. 13, 5791 (2022)
In insulating crystals, it was previously shown that defects with two fewer dimensions than the bulk can bind topological electronic states. We here further extend the classification of topological defect states by demonstrating that the corners of c
Externí odkaz:
http://arxiv.org/abs/2207.10112
Autor:
Lin, Kuan-Sen, Palumbo, Giandomenico, Guo, Zhaopeng, Hwang, Yoonseok, Blackburn, Jeremy, Shoemaker, Daniel P., Mahmood, Fahad, Wang, Zhijun, Fiete, Gregory A., Wieder, Benjamin J., Bradlyn, Barry
Publikováno v:
Nature Communications 15, 550 (2024)
Symmetry-protected topological crystalline insulators (TCIs) have primarily been characterized by their gapless boundary states. However, in time-reversal- ($\mathcal{T}$-) invariant (helical) 3D TCI$\unicode{x2014}$termed higher-order TCIs (HOTIs)$\
Externí odkaz:
http://arxiv.org/abs/2207.10099
Autor:
Gordon B. Bonan, Oliver Lucier, Deborah R. Coen, Adrianna C. Foster, Jacquelyn K. Shuman, Marysa M. Laguë, Abigail L. S. Swann, Danica L. Lombardozzi, William R. Wieder, Kyla M. Dahlin, Adrian V. Rocha, Michael D. SanClements
Publikováno v:
Journal of Advances in Modeling Earth Systems, Vol 16, Iss 8, Pp n/a-n/a (2024)
Abstract Terrestrial, aquatic, and marine ecosystems regulate climate at local to global scales through exchanges of energy and matter with the atmosphere and assist with climate change mitigation through nature‐based climate solutions. Climate sci
Externí odkaz:
https://doaj.org/article/61f6153125834e71a5055adbcbf19050