Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Wiebke Nadolni"'
Autor:
Monika I. Hollenhorst, Rajender Nandigama, Saskia B. Evers, Igor Gamayun, Noran Abdel Wadood, Alaa Salah, Mario Pieper, Amanda Wyatt, Alexey Stukalov, Anna Gebhardt, Wiebke Nadolni, Wera Burow, Christian Herr, Christoph Beisswenger, Soumya Kusumakshi, Fabien Ectors, Tatjana I. Kichko, Lisa Hübner, Peter Reeh, Antje Munder, Sandra-Maria Wienhold, Martin Witzenrath, Robert Bals, Veit Flockerzi, Thomas Gudermann, Markus Bischoff, Peter Lipp, Susanna Zierler, Vladimir Chubanov, Andreas Pichlmair, Peter König, Ulrich Boehm, Gabriela Krasteva-Christ
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 13 (2022)
Constant exposure of the airways to inhaled pathogens requires efficient early immune responses protecting against infections. How bacteria on the epithelial surface are detected and first-line protective mechanisms are initiated are not well underst
Externí odkaz:
https://doaj.org/article/b6c462ddd8474b69bfe5c8500b0b830e
Autor:
Wiebke Nadolni, Roland Immler, Kilian Hoelting, Marco Fraticelli, Myriam Ripphahn, Simone Rothmiller, Masayuki Matsushita, Ingrid Boekhoff, Thomas Gudermann, Markus Sperandio, Susanna Zierler
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
During inflammation, neutrophils are one of the first responding cells of innate immunity, contributing to a fast clearance of infection and return to homeostasis. However, excessive neutrophil infiltration accelerates unsolicited disproportionate in
Externí odkaz:
https://doaj.org/article/7c8ee04e5a11479d9b310f0f5b376134
Autor:
Andrea Romagnani, Valentina Vettore, Tanja Rezzonico-Jost, Sarah Hampe, Elsa Rottoli, Wiebke Nadolni, Michela Perotti, Melanie A. Meier, Constanze Hermanns, Sheila Geiger, Gunther Wennemuth, Camilla Recordati, Masayuki Matsushita, Susanne Muehlich, Michele Proietti, Vladimir Chubanov, Thomas Gudermann, Fabio Grassi, Susanna Zierler
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Gut-homing and colonization of T cells are important for maintaining local immune homoeostasis and protective immunity. Here the authors show that the kinase activity of TRPM7 regulates Th17 differentiation and T cell alloreactivity in the gut by mod
Externí odkaz:
https://doaj.org/article/81c11da70637480eb4d002bc8644c76b
Autor:
Wiebke Nadolni, Susanna Zierler
Publikováno v:
Cells, Vol 7, Iss 8, p 109 (2018)
The enzyme-coupled transient receptor potential channel subfamily M member 7, TRPM7, has been associated with immunity and immune cell signalling. Here, we review the role of this remarkable signalling protein in lymphocyte proliferation, differentia
Externí odkaz:
https://doaj.org/article/169a9a62969e493794423f33098eee48
Autor:
Birgit Hoeger, Wiebke Nadolni, Sarah Hampe, Kilian Hoelting, Marco Fraticelli, Nadja Zaborsky, Anna Madlmayr, Viktoria Sperrer, Laura Fraticelli, Lynda Addington, Dirk Steinritz, Vladimir Chubanov, Roland Geisberger, Richard Greil, Andreas Breit, Ingrid Boekhoff, Thomas Gudermann, Susanna Zierler
Cyclooxygenase-2 (COX-2) is a key regulator of inflammation. High constitutive COX-2 expression enhances survival and proliferation of tumor cells, whereas it adversely impacts anti-tumor immunity. We recently identified the melastatin-like transient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8374d52eaed27635ab2c7d59a5de35ff
https://doi.org/10.21203/rs.3.rs-2405917/v1
https://doi.org/10.21203/rs.3.rs-2405917/v1
Autor:
Eytan R Barnea, Ina Rohwedder, Thomas Gudermann, Sergi Masgrau-Alsina, Susanna Zierler, Scott I. Simon, Anna Yevtushenko, Markus Sperandio, Oliver Soehnlein, Annika Bertsch, Roland Immler, Markus Moser, Wiebke Nadolni, Markus Rehberg, Monika Pruenster, Tobias Schroll, Vasilios A. Morikis
Publikováno v:
Cardiovasc. Res. 118, 1289–1302 (2022)
Aims Neutrophil trafficking within the vasculature strongly relies on intracellular calcium signaling. Sustained Ca2+ influx into the cell requires a compensatory efflux of potassium to maintain membrane potential. Here, we aimed to investigate wheth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3086c045419381c6b4e58c771708946a
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=61889
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=61889
Autor:
Thomas J O'Neill, Martin Biel, Andreas Breit, Thomas Gudermann, Elisabeth Arlt, Christian Wahl-Schott, Gunther Wennemuth, Susanna Zierler, Marc Freichel, Wiebke Nadolni, Marco Fraticelli, Volodymyr Tsvilovskyy, Christian Grimm, Stefanie Resenberger, Ingrid Boekhoff, Norbert Klugbauer
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 117(30)
Mast cells and basophils are main drivers of allergic reactions and anaphylaxis, for which prevalence is rapidly increasing. Activation of these cells leads to a tightly controlled release of inflammatory mediators stored in secretory granules. The r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7775ec7c25dc57139fa33f4d5b344d8
https://pubmed.ncbi.nlm.nih.gov/33027744
https://pubmed.ncbi.nlm.nih.gov/33027744
Autor:
Gunther Wennemuth, Susanna Zierler, Wiebke Nadolni, Constanze Hermanns, Masayuki Matsushita, Valentina Vettore, Susanne Muehlich, Elsa Rottoli, Michele Proietti, Camilla Recordati, Michela Perotti, Thomas Gudermann, Fabio Grassi, Vladimir Chubanov, Sarah Hampe, Tanja Rezzonico-Jost, Melanie A Meier, Andrea Romagnani, Sheila Geiger
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Nature Communications
Nature Communications
The melastatin-like transient-receptor-potential-7 protein (TRPM7), harbouring a cation channel and a serine/threonine kinase, has been implicated in thymopoiesis and cytokine expression. Here we show, by analysing TRPM7 kinase-dead mutant (Trpm7 R/R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b12c7d2a0fa9281bc07a9f0d5a60e3f6
http://doc.rero.ch/record/327179/files/Romagnani_NC_2017.pdf
http://doc.rero.ch/record/327179/files/Romagnani_NC_2017.pdf
Autor:
Laura Schreyer, Susanne Muehlich, Wiebke Nadolni, Vladimir Chubanov, Kerstin Holzer, Silvia Ferioli, Stephan Singer, Susanna Zierler, Bernhard Liebl, Constanze Mittermeier, Katharina Woerther, Sandra Voringer, Thomas Gudermann, Melanie A Meier
Publikováno v:
Oncogene. 39(11)
Myocardin-related transcription factors A and B (MRTFs) are coactivators of Serum Response Factor (SRF) that mediates the expression of genes involved in cell proliferation, migration and differentiation. There is mounting evidence that MRTFs and SRF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18fcaf6bc65ff1db0aec86848c270b93
https://pubmed.ncbi.nlm.nih.gov/31844251
https://pubmed.ncbi.nlm.nih.gov/31844251
Autor:
Susanna Zierler, Wiebke Nadolni
Publikováno v:
Cells, Vol 7, Iss 8, p 109 (2018)
Cells
Cells
The enzyme-coupled transient receptor potential channel subfamily M member 7, TRPM7, has been associated with immunity and immune cell signalling. Here, we review the role of this remarkable signalling protein in lymphocyte proliferation, differentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed76d59c84c38c4d695da5c17a68a6b1
http://www.mdpi.com/2073-4409/7/8/109
http://www.mdpi.com/2073-4409/7/8/109