Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Wiebke Herzog"'
Autor:
Dorothee Bornhorst, Peng Xia, Hiroyuki Nakajima, Chaitanya Dingare, Wiebke Herzog, Virginie Lecaudey, Naoki Mochizuki, Carl-Philipp Heisenberg, Deborah Yelon, Salim Abdelilah-Seyfried
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
It is unknown how endocardium growth is coordinated with that of the myocardium in the zebrafish. Here, the authors show that myocardial chamber volume expansion causes increased endocardial tissue tension, which in turn triggers Hippo signaling-medi
Externí odkaz:
https://doaj.org/article/c9a01fbb92ac4026a8b8af2a31775f44
Autor:
Alice Neal, Svanhild Nornes, Sophie Payne, Marsha D. Wallace, Martin Fritzsche, Pakavarin Louphrasitthiphol, Robert N. Wilkinson, Kira M. Chouliaras, Ke Liu, Karen Plant, Radhika Sholapurkar, Indrika Ratnayaka, Wiebke Herzog, Gareth Bond, Tim Chico, George Bou-Gharios, Sarah De Val
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
The establishment of functional vasculatures requires the specification of newly formed vessels into veins and arteries. Here, Neal et al. use a combination of genetic approaches in mice and zebrafish to show that BMP signalling, via ALK3 and SMAD1/5
Externí odkaz:
https://doaj.org/article/10b6663419654c3aa3496b47db2a99e8
Autor:
Kathleen Hübner, Pauline Cabochette, Rodrigo Diéguez-Hurtado, Cora Wiesner, Yuki Wakayama, Kathrin S. Grassme, Marvin Hubert, Stefan Guenther, Heinz-Georg Belting, Markus Affolter, Ralf H. Adams, Benoit Vanhollebeke, Wiebke Herzog
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Wnt signaling is known to regulate the formation of the blood-brain barrier. Here Hübner et al. dissect the underlying mechanisms using high resolution live imaging in zebrafish, and find that Wnt regulates anastomosis of angiogenic sprouts in the b
Externí odkaz:
https://doaj.org/article/24e4c6a49599424898a125c7c9be3b6f
Autor:
Christian SM Helker, Jean Eberlein, Kerstin Wilhelm, Toshiya Sugino, Julian Malchow, Annika Schuermann, Stefan Baumeister, Hyouk-Bum Kwon, Hans-Martin Maischein, Michael Potente, Wiebke Herzog, Didier YR Stainier
Publikováno v:
eLife, Vol 9 (2020)
To form new blood vessels (angiogenesis), endothelial cells (ECs) must be activated and acquire highly migratory and proliferative phenotypes. However, the molecular mechanisms that govern these processes are incompletely understood. Here, we show th
Externí odkaz:
https://doaj.org/article/a7756ce122b04439b2b330f101fbb2e6
Autor:
Stephanie Grainger, Jenna Richter, Raquel Espín Palazón, Claire Pouget, Brianna Lonquich, Sara Wirth, Kathrin Sabine Grassme, Wiebke Herzog, Matthew R. Swift, Brant M. Weinstein, David Traver, Karl Willert
Publikováno v:
Cell Reports, Vol 17, Iss 6, Pp 1595-1606 (2016)
All mature blood cell types in the adult animal arise from hematopoietic stem and progenitor cells (HSPCs). However, the developmental cues regulating HSPC ontogeny are incompletely understood. In particular, the details surrounding a requirement for
Externí odkaz:
https://doaj.org/article/41708572565849e5a7e7ccb860acec85
Autor:
Hyouk-Bum Kwon, Shengpeng Wang, Christian S. M. Helker, S. Javad Rasouli, Hans-Martin Maischein, Stefan Offermanns, Wiebke Herzog, Didier Y. R. Stainier
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Endothelial cells align in the direction of flow in response to shear stress. Here the authors describe a zebrafish model for visualization of endothelial polarization and demonstrate that endothelial cell alignment depends on blood flow and Apelin s
Externí odkaz:
https://doaj.org/article/eac965749fac40fca0169a882620ff6c
Autor:
Damir Jacob Illich, Miao Zhang, Andrei Ursu, Rodrigo Osorno, Kee-Pyo Kim, Juyong Yoon, Marcos J. Araúzo-Bravo, Guangming Wu, Daniel Esch, Davood Sabour, Douglas Colby, Kathrin S. Grassme, Jiayu Chen, Boris Greber, Susanne Höing, Wiebke Herzog, Slava Ziegler, Ian Chambers, Shaorong Gao, Herbert Waldmann, Hans R. Schöler
Publikováno v:
Cell Reports, Vol 15, Iss 4, Pp 787-800 (2016)
It has previously been reported that mouse epiblast stem cell (EpiSC) lines comprise heterogeneous cell populations that are functionally equivalent to cells of either early- or late-stage postimplantation development. So far, the establishment of th
Externí odkaz:
https://doaj.org/article/bcd0b9b6536d410aacc68d28af505701
Autor:
Ryota L Matsuoka, Michele Marass, Avdesh Avdesh, Christian SM Helker, Hans-Martin Maischein, Ann S Grosse, Harmandeep Kaur, Nathan D Lawson, Wiebke Herzog, Didier YR Stainier
Publikováno v:
eLife, Vol 5 (2016)
Vascular networks surrounding individual organs are important for their development, maintenance, and function; however, how these networks are assembled remains poorly understood. Here we show that CNS progenitors, referred to as radial glia, modula
Externí odkaz:
https://doaj.org/article/1e58fcdc1ced422e83652512f7cbad98
Autor:
Christian SM Helker, Annika Schuermann, Cathrin Pollmann, Serene C Chng, Friedemann Kiefer, Bruno Reversade, Wiebke Herzog
Publikováno v:
eLife, Vol 4 (2015)
A key step in the de novo formation of the embryonic vasculature is the migration of endothelial precursors, the angioblasts, to the position of the future vessels. To form the first axial vessels, angioblasts migrate towards the midline and coalesce
Externí odkaz:
https://doaj.org/article/3cc606838efc4427828ca79d15ea9569
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41116 (2012)
Notch signaling controls fundamental aspects of angiogenic blood vessel growth including the selection of sprouting tip cells, endothelial proliferation and arterial differentiation. The E3 ubiquitin ligase Fbxw7 is part of the SCF protein complex re
Externí odkaz:
https://doaj.org/article/79b986596e4349819b96c8c2f4b21276