Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Wiebke Handke"'
Autor:
Marline Kirsch, Jessica Rach, Wiebke Handke, Axel Seltsam, Iliyana Pepelanova, Sarah Strauß, Peter Vogt, Thomas Scheper, Antonina Lavrentieva
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2021)
In vitro two-dimensional (2D) and three-dimensional (3D) cultivation of mammalian cells requires supplementation with serum. Mesenchymal stem cells (MSCs) are widely used in clinical trials for bioregenerative medicine and in most cases, in vitro exp
Externí odkaz:
https://doaj.org/article/4ae9c8fc372241b08b3a846918603190
Autor:
Marline Kirsch, Annabelle-Christin Herder, Cécile Boudot, Andreas Karau, Jessica Rach, Wiebke Handke, Axel Seltsam, Thomas Scheper, Antonina Lavrentieva
Publikováno v:
Materials, Vol 13, Iss 15, p 3399 (2020)
The development of alloplastic resorbable materials can revolutionize the field of implantation technology in regenerative medicine. Additional opportunities to colonize the three-dimensionally (3D) printed constructs with the patient’s own cells p
Externí odkaz:
https://doaj.org/article/7be3427a897a4101ae183a9c4330a594
Autor:
Marline Kirsch, Luise Birnstein, Iliyana Pepelanova, Wiebke Handke, Jessica Rach, Axel Seltsam, Thomas Scheper, Antonina Lavrentieva
Publikováno v:
Bioengineering, Vol 6, Iss 3, p 76 (2019)
Three-dimensional (3D) cell culture is a major focus of current research, since cultivation under physiological conditions provides more reliable information about in vivo cell behavior. 3D cell cultures are used in basic research to better understan
Externí odkaz:
https://doaj.org/article/e7b8ef4be811458eb7519d33524e0c62
Akademický článek
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Autor:
Wiebke Handke, Ute Gravemann, Thomas H. Müller, Franz F. Wagner, Torsten J. Schulze, Axel Seltsam
Publikováno v:
Transfusion. 62:2314-2323
Pathogen inactivation (PI) technologies for platelet concentrates and plasma are steadily becoming more established, but new PI treatment options for red blood cells (RBCs), the most commonly used blood component, still need to be developed. We prese
Autor:
Thomas R. L. Klei, Stephane Begue, Anaïs Lotens, Ólafur E. Sigurjónsson, Michael D. Wiltshire, Chloë George, Peter J. M. van den Burg, Ryan Evans, Linda Larsson, Stephen Thomas, Tome Najdovski, Wiebke Handke, Juha Eronen, Birte Mallas, Dirk de Korte
Publikováno v:
Vox sanguinisREFERENCES.
DEHP, di(2-ethylhexyl) phthalate, is the most common member of the class of ortho-phthalates, which are used as plasticizers. The Medical Device Regulation has restricted the use of phthalates in medical devices. Also DEHP has been added to the Annex
Publikováno v:
Transfusion. 60:1821-1827
Background UVC illumination of agitated platelet concentrates (PCs) inactivates pathogens and white blood cells by modifications of their nucleic acids. Related effects on mitochondrial DNA (mtDNA) in platelets serve as a basis for an efficient monit
Autor:
Axel Seltsam, Frank Tolksdorf, Markus Eickmann, Thomas Müller, Wiebke Handke, Ute Gravemann, Stefan Reichenberg
Publikováno v:
Vox Sanguinis
Background Emerging viruses like severe acute respiratory syndrome coronavirus (SARS-CoV), Crimean-Congo haemorrhagic fever virus (CCHFV) and Nipah virus (NiV) have been identified to pose a potential threat to transfusion safety. In this study, the
Publikováno v:
Transfusion. 59:1324-1332
Background The THERAFLEX UV-Platelets system (Maco Pharma) uses ultraviolet C (UVC) light for pathogen inactivation (PI) of platelet concentrates (PCs) without any additional photoactive compound. The aim of the study was to systematically investigat
Autor:
Martina Friesland, Ute Gravemann, Thomas Müller, Wiebke Handke, Daniel Todt, Patrick Behrendt, Axel Seltsam, Dimas F. Praditya, Eike Steinmann
Publikováno v:
Vox sanguinisReferences. 115(7)
Background and objectives As previous investigations have shown, THERAFLEX UV-Platelets, a UVC-based pathogen inactivation (PI) system, is effective against non-enveloped transfusion-relevant viruses such as hepatitis A virus (HAV), which are insensi