Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Wiebke Chemnitz"'
Autor:
Wen Luo, Hai Hoang, Katherine E. Miller, Hongwen Zhu, Serena Xu, Xiaokui Mo, Elizabeth A. R. Garfinkle, Heather Costello, Saranga Wijeratne, Wiebke Chemnitz, Ronan Gandhi, Yanling Liao, Janet Ayello, Aliza Gardenswartz, Jeremy M. Rosenblum, Kevin A. Cassady, Elaine R. Mardis, Dean A. Lee, Timothy P. Cripe, Mitchell S. Cairo
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-17 (2024)
Abstract Background Macrophages play important roles in phagocytosing tumor cells. However, tumors escape macrophage phagocytosis in part through the expression of anti-phagocytic signals, most commonly CD47. In Ewing sarcoma (ES), we found that tumo
Externí odkaz:
https://doaj.org/article/ef612054309d4f2fb16fbb5249bba11b
Autor:
Kang, Young-Hoon, Farina, Andrea, Bermudez, Vladimir P., Tappin, Inger, Du, Fang, Galal, Wiebke Chemnitz, Hurwitz, Jerard
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2013 Dec 01. 110(49), 19760-19765.
Externí odkaz:
https://www.jstor.org/stable/23758307
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2012 Apr . 109(16), 6042-6047.
Externí odkaz:
https://www.jstor.org/stable/41588470
Autor:
Jerard Hurwitz, Young-Hoon Kang, Vladimir P. Bermudez, Fang Du, Andrea Farina, Wiebke Chemnitz Galal, Inger Tappin
Publikováno v:
Proceedings of the National Academy of Sciences. 110:19760-19765
Chromosome transmission fidelity 4 (Ctf4) is a conserved protein required for DNA replication. In this report, interactions between human Ctf4 (hCtf4) and the replicative helicase containing the cell division cycle 45 (Cdc45)/minichromosome maintenan
Autor:
James L. Edwards, Miao Pan, Wei Yuan, Wiebke Chemnitz Galal, Jerard Hurwitz, Gary G. Giulian, Zvi Kelman, John P. Marino, Shuwei Li
Publikováno v:
Journal of Biological Chemistry. 287:16220-16229
In the presence of dATP, glycerol, and Tris buffer, the DNA primase isolated from Thermococcus kodakaraensis catalyzed the formation of dAMP and two products that were identified as dAMP-glycerol and dAMP-Tris. These products were formed by the T. ko
Autor:
Miao Pan, Wei Yuan, Zhuo Li, Jerard Hurwitz, Thomas J. Santangelo, Zvi Kelman, James L. Edwards, Wiebke Chemnitz, John N. Reeve
Publikováno v:
Nucleic Acids Research
Chromosomal DNA replication requires the spatial and temporal coordination of the activities of several complexes that constitute the replisome. A previously uncharacterized protein, encoded by TK1252 in the archaeon Thermococcus kodakaraensis, was s
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 109(16)
In eukaryotes, although the Mcm2-7 complex is a key component of the replicative DNA helicase, its association with Cdc45 and GINS (the CMG complex) is required for the activation of the DNA helicase. Here, we show that the CMG complex is localized t
Publikováno v:
The Journal of biological chemistry. 287(20)
In most organisms, DNA replication is initiated by DNA primases, which synthesize primers that are elongated by DNA polymerases. In this study, we describe the isolation and biochemical characterization of the DNA primase complex and its subunits fro
Publikováno v:
Cell Cycle
In eukaryotes, the complex comprised of Mcm2–7, Cdc45 and GINS (CMG) is essential for DNA replication. Several lines of evidence indicate that the Mcm2–7 complex is the motor of the replicative helicase (reviewed in ref. 1), which is activated by
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