Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Wiebke, Sihver"'
Autor:
Wiebke Sihver, Anne-Kathrin Nitt-Weber, Stephan Behrens, Martin Ullrich, Hans-Jürgen Pietzsch, Negin Namazian Jam, Florian Schmieder, Frank Sonntag
Publikováno v:
Current Directions in Biomedical Engineering. 8:532-535
Radiopharmaceuticals can be used for targetspecific functional diagnostics, such as PET or SPECT imaging, or radionuclide therapy of diseased tissue, depending on the incorporated radionuclide. Following initial in vitro testing, radiopharmaceutical
Autor:
Franziska Striese, Christin Neuber, Sandy Gräßel, Claudia Arndt, Martin Ullrich, Jörg Steinbach, Jens Pietzsch, Ralf Bergmann, Hans-Jürgen Pietzsch, Wiebke Sihver, Marcus Frenz, Anja Feldmann, Michael P. Bachmann
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9420
Prostate specific membrane antigen (PSMA) is an excellent target for imaging and treatment of prostate carcinoma (PCa). Unfortunately, not all PCa cells express PSMA. Therefore, alternative theranostic targets are required. The membrane protein prost
Autor:
Wiebke Sihver, Jens Pietzsch, Mechthild Krause, Michael Baumann, Jörg Steinbach, Hans-Jürgen Pietzsch
Publikováno v:
Pharmaceuticals, Vol 7, Iss 3, Pp 311-338 (2014)
The epidermal growth factor receptor (EGFR) has evolved over years into a main molecular target for the treatment of different cancer entities. In this regard, the anti-EGFR antibody cetuximab has been approved alone or in combination with: (a) chemo
Externí odkaz:
https://doaj.org/article/811e2bf1eabe4247b3131cadf7bfad32
Autor:
Felix Neumaier, Annette Schulze, Birte Drewes, Wiebke Sihver, Dirk Bier, Franziska Wedekind, Marcus H. Holschbach, Bernd Neumaier, Andreas Bauer
Publikováno v:
Journal of radioanalytical and nuclear chemistry 326(3), 1691-1697 (2020). doi:10.1007/s10967-020-07465-2
5-Iodotubercidin is a prototype adenosine kinase (AK) inhibitor with potent anti-seizure activity in rodent epilepsy models. Using the chloramine-T method for radioiodination of tubercidin with 131I, we prepared no-carrier-added 5-[131I]iodotubercidi
Autor:
Wiebke Sihver, Nico Liske, Robert Wodtke, Florian Brandt, Martin Walther, Michael Bachmann, Klaus Kopka, Hans-Jurgen Pietzsch
Publikováno v:
Nuclear Medicine and Biology 108-109(2022)Suppl. 1, P-300
Objective: The somatostatin receptor subtype 2 (SSTR2) is a suitable target for the diagnosis and therapy of neuroendocrine tumors using radiolabeled ligands [1]. BON-1S cells have been described to express SSTR2 receptors in vitro [2]. We therefore
Autor:
Antje, Dietrich, Michael, Andreeff, Lydia, Koi, Ralf, Bergmann, Maik, Schubert, Lena, Schreiner, Steffen, Löck, Wiebke, Sihver, Robert, Freudenberg, Sandra, Hering, Hans-Jürgen, Pietzsch, Jörg, Steinbach, Jörg, Kotzerke, Michael, Baumann, Mechthild, Krause
Publikováno v:
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 161
Autor:
Lydia Koi, Maik Schubert, Jörg Steinbach, Wiebke Sihver, Michael Andreeff, Hans-Jürgen Pietzsch, Michael Baumann, Ralf Bergmann, Antje Dietrich, Lena Schreiner, Mechthild Krause, Robert Freudenberg, Jörg Kotzerke, Sandra Hering, Steffen Löck
Publikováno v:
Radiotherapy and Oncology 155(2021), 285-292
Background and purpose Systemic molecular radiotherapy utilizes internal irradiation by radionuclide-labeled tumor-targeting agents with the potential to destroy (micro-)metastases. However, doses that are applicable in solid tumors do not reach the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8650f0d9130c446f0f8bd6fb4f595628
https://www.hzdr.de/publications/Publ-32289-1
https://www.hzdr.de/publications/Publ-32289-1
Autor:
Maik Schubert, Jörg Steinbach, Steffen Löck, Michael Andreeff, Michael Baumann, Hans-Jürgen Pietzsch, Mechthild Krause, Antje Dietrich, Ralf Bergmann, Jörg Kotzerke, Lydia Koi, Lena Schreiner, Robert Freudenberg, Sandra Hering, Wiebke Sihver
Publikováno v:
Radiotherapy and Oncology. 161:261-262
Autor:
Jörg Steinbach, Feng Gao, Hans-Jürgen Pietzsch, Ralf Bergmann, Jens Pietzsch, Franziska Striese, Wiebke Sihver, Martin Walther
Publikováno v:
Amino Acids. 50:1415-1431
The epidermal growth factor receptor (EGFR) represents an important molecular target for both radiotracer-based diagnostic imaging and radionuclide therapy of various cancer entities. For the delivery of radionuclides to the tumor, peptides hold grea
Autor:
Mechthild Krause, Ariane Christel Kühn, Louis Feindt, Annett Linge, Michael Baumann, Cläre von Neubeck, Lydia Koi, Hans-Jürgen Pietzsch, Antje Dietrich, Wiebke Sihver, Jörg Kotzerke, Robert Freudenberg, Johannes Müller, Enes Cevik, Treewut Rassamegevanon, Steffen Löck
Publikováno v:
Cancers
Cancers, Vol 13, Iss 5595, p 5595 (2021)
Cancers 13(2021)22, 5595
Volume 13
Issue 22
Cancers, Vol 13, Iss 5595, p 5595 (2021)
Cancers 13(2021)22, 5595
Volume 13
Issue 22
Combination treatment of molecular targeted and external radiotherapy is a promising strategy and was shown to improve local tumor control in a HNSCC xenograft model. To enhance the therapeutic value of this approach, this study investigated the unde