Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Wiebke, Hartmann"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Helminths are large multicellular parasites that infect one quarter of the human population. To prolong their survival, helminths suppress the immune responses of their hosts. Strongyloides ratti delays its expulsion from the gut by inductio
Externí odkaz:
https://doaj.org/article/f3c26d072329439ea2776bc719c1441d
Autor:
Alexandra Ehrens, Nikolas Rüdiger, Lennart Heepmann, Lara Linnemann, Wiebke Hartmann, Marc P. Hübner, Minka Breloer
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/d4a0a52099844381bee7f3b7a7e1ef95
Publikováno v:
PLoS ONE, Vol 17, Iss 3, p e0266456 (2022)
The world health organization estimates that more than a quarter of the human population is infected with parasitic worms that are called helminths. Many helminths suppress the immune system of their hosts to prolong their survival. This helminth-ind
Externí odkaz:
https://doaj.org/article/a6796fae088240d29363374a54ecf60a
Autor:
Nadine Stetter, Wiebke Hartmann, Marie-Luise Brunn, Stephanie Stanelle-Bertram, Gülsah Gabriel, Minka Breloer
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Helminths still infect a quarter of the human population. They manage to establish chronic infections by downmodulating the immune system of their hosts. Consequently, the immune response of helminth-infected individuals to vaccinations may be impair
Externí odkaz:
https://doaj.org/article/ba2e5fa5e31d4be7a2d99b0402c31a51
Autor:
Alexandra Ehrens, Nikolas Rüdiger, Lennart Heepmann, Lara Linnemann, Wiebke Hartmann, Marc P. Hübner, Minka Breloer
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Parasitic nematodes such as hookworms actively penetrate the skin of their hosts, encountering skin-resident innate immune cells that represent the host´s first line of defense. Here we use Strongyloides ratti as a model for an intestinal helminth p
Externí odkaz:
https://doaj.org/article/5874c8a2b2ac49949d98e9dfb0b2b8b1
Autor:
Michael Delacher, Christian Schmidl, Yonatan Herzig, Minka Breloer, Wiebke Hartmann, Fabian Brunk, Danny Kägebein, Ulrike Träger, Ann-Cathrin Hofer, Sebastian Bittner, Dieter Weichenhan, Charles D. Imbusch, Agnes Hotz-Wagenblatt, Thomas Hielscher, Achim Breiling, Giuseppina Federico, Hermann-Josef Gröne, Roland M. Schmid, Michael Rehli, Jakub Abramson, Markus Feuerer
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-20 (2019)
Transcriptional regulator Rbpj is involved in T-helper subset differentiation. Here the authors show that expression of Rbpj in regulatory T cells is required to both regulate TH2 responses and regulate Treg TH2 differentiation potential.
Externí odkaz:
https://doaj.org/article/f8c425dfd10a45c698bf9c4a6526c87e
Autor:
Minka Breloer, Wiebke Hartmann
Publikováno v:
Immunology Letters. 255:62-66
Autor:
Jana Meiners, Martina Reitz, Nikolas Rüdiger, Jan-Eric Turner, Lennart Heepmann, Lena Rudolf, Wiebke Hartmann, Henry J McSorley, Minka Breloer
Publikováno v:
PLoS Pathogens, Vol 16, Iss 12, p e1009121 (2020)
Parasitic helminths are sensed by the immune system via tissue-derived alarmins that promote the initiation of the appropriate type 2 immune responses. Here we establish the nuclear alarmin cytokine IL-33 as a non-redundant trigger of specifically IL
Externí odkaz:
https://doaj.org/article/58d2186793aa4aa690c31ab0a26af445
Autor:
Lara Christine Linnemann, Martina Reitz, Thorsten B Feyerabend, Minka Breloer, Wiebke Hartmann
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 7, p e0008534 (2020)
Mast cells are innate effector cells that due to their localization in the tissue form the first line of defense against parasites. We have previously shown that specifically mucosal mast cells were essential for the termination of the intestinal Str
Externí odkaz:
https://doaj.org/article/4c01a216f5f94c8da75097922d414f65
Autor:
Wiebke Hartmann, Marie-Luise Brunn, Nadine Stetter, Nicola Gagliani, Franziska Muscate, Stephanie Stanelle-Bertram, Gülsah Gabriel, Minka Breloer
Publikováno v:
Cell Reports, Vol 29, Iss 8, Pp 2243-2256.e4 (2019)
Summary: Helminth parasites infect more than a quarter of the human population and inflict significant changes to the immunological status of their hosts. Here, we analyze the impact of helminth infections on the efficacy of vaccinations using Litomo
Externí odkaz:
https://doaj.org/article/6d41aff946264f798fe526a4d6eafe27