Zobrazeno 1 - 10 of 192 pro vyhledávání: '"Wickenhagen, A"'
1
Akademický článek
Jamaican fruit bat (Artibeus jamaicensis) insusceptibility to mucosal inoculation with SARS-CoV-2 Delta variant is not caused by receptor compatibility
Autor: Julia R. Port, Jade C. Riopelle, Sarah van Tol, Arthur Wickenhagen, Eric Bohrnsen, Daniel E. Sturdevant, Rebecca Rosenke, Jamie Lovaglio, Justin Lack, Sarah L. Anzick, Kathleen Cordova, Kwe Claude Yinda, Patrick W. Hanley, Tony Schountz, Lon V. Kendall, Carl I. Shaia, Greg Saturday, Craig Martens, Benjamin Schwarz, Vincent J. Munster
Publikováno v: npj Viruses, Vol 2, Iss 1, Pp 1-15 (2024)
Abstract The ancestral sarbecovirus giving rise to SARS-CoV-2 is posited to have originated in bats. While SARS-CoV-2 causes asymptomatic to severe respiratory disease in humans, little is known about the biology, virus tropism, and immunity of SARS-
Externí odkaz: https://doaj.org/article/04082be39d684a2987f4130c09c16462
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2
Report
Bichromatic UV detection system for atomically-resolved imaging of ions
Autor: Nordmann, T., Wickenhagen, S., Doležal, M., Mehlstäubler, T. E.
We present a compact and bichromatic imaging system, located outside of the vacuum chamber of a trapped ion apparatus, that collects the fluorescence of 230.6 nm and 369.5 nm photons simultaneously on a shared EMCCD camera. The system contains two le
Externí odkaz: http://arxiv.org/abs/2302.02489
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3
Akademický článek
Resurrection of 2'-5'-oligoadenylate synthetase 1 (OAS1) from the ancestor of modern horseshoe bats blocks SARS-CoV-2 replication.
Autor: Spyros Lytras, Arthur Wickenhagen, Elena Sugrue, Douglas G Stewart, Simon Swingler, Anna Sims, Hollie Jackson Ireland, Emma L Davies, Eliza M Ludlam, Zhuonan Li, Joseph Hughes, Sam J Wilson
Publikováno v: PLoS Biology, Vol 21, Iss 11, p e3002398 (2023)
The prenylated form of the human 2'-5'-oligoadenylate synthetase 1 (OAS1) protein has been shown to potently inhibit the replication of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the virus responsible for the Coronavirus Disease 20
Externí odkaz: https://doaj.org/article/044c4448a3ee4d4ab82590b54230a869
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4
Akademický článek
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5
Akademický článek
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6
Akademický článek
Human metapneumovirus driven IFN-β production antagonizes macrophage transcriptional induction of IL1-β in response to bacterial pathogens
Autor: Simon Loevenich, Nicola P. Montaldo, Arthur Wickenhagen, Tatyana Sherstova, Barbara van Loon, Victor Boyartchuk, Marit W. Anthonsen
Publikováno v: Frontiers in Immunology, Vol 14 (2023)
Human metapneumovirus (HMPV) is a pneumovirus that may cause severe respiratory disease in humans. HMPV infection has been found to increase susceptibility to bacterial superinfections leading to increased morbidity and mortality. The molecular mecha
Externí odkaz: https://doaj.org/article/2f7c75507af942d99e8d201f9636c812
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7
Akademický článek
Resurrection of 2′-5′-oligoadenylate synthetase 1 (OAS1) from the ancestor of modern horseshoe bats blocks SARS-CoV-2 replication.
Autor: Lytras, Spyros1 (AUTHOR) spyros.lytras@glasgow.ac.uk, Wickenhagen, Arthur1 (AUTHOR), Sugrue, Elena1 (AUTHOR), Stewart, Douglas G.1 (AUTHOR), Swingler, Simon1 (AUTHOR), Sims, Anna1 (AUTHOR), Jackson Ireland, Hollie1 (AUTHOR), Davies, Emma L.1 (AUTHOR), Ludlam, Eliza M.1 (AUTHOR), Li, Zhuonan1 (AUTHOR), Hughes, Joseph1 (AUTHOR), Wilson, Sam J.1,2 (AUTHOR) spyros.lytras@glasgow.ac.uk
Publikováno v: PLoS Biology. 11/28/2023, Vol. 21 Issue 11, p1-17. 17p.
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8
Akademický článek
The apparent interferon resistance of transmitted HIV-1 is possibly a consequence of enhanced replicative fitness.
Autor: Elena Sugrue, Arthur Wickenhagen, Nardus Mollentze, Muhamad Afiq Aziz, Vattipally B Sreenu, Sven Truxa, Lily Tong, Ana da Silva Filipe, David L Robertson, Joseph Hughes, Suzannah J Rihn, Sam J Wilson
Publikováno v: PLoS Pathogens, Vol 18, Iss 11, p e1010973 (2022)
HIV-1 transmission via sexual exposure is an inefficient process. When transmission does occur, newly infected individuals are colonized by the descendants of either a single virion or a very small number of establishing virions. These transmitted fo
Externí odkaz: https://doaj.org/article/312eb46f19e0404c960c54ff41b6efb3
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9
Akademický článek
Quantitative proteomic analysis of SARS-CoV-2 infection of primary human airway ciliated cells and lung epithelial cells demonstrates the effectiveness of SARS-CoV-2 innate immune evasion [version 1; peer review: 2 approved]
Autor: Paul J. Lehner, Frank McCaughan, Edward J.D. Greenwood, Thomas W.M. Crozier, Wenrui Guo, James C. Williamson, Ildar Gabaev, Linsey M. Porter, Guinevere L. Grice, Ana Teixeira-Silva, Richard J. Stanton, Arthur Wickenhagen, Sam J. Wilson, Eddie C. Y. Wang, James A. Nathan, Nicholas J. Matheson
Publikováno v: Wellcome Open Research, Vol 7 (2022)
Background: Quantitative proteomics is able to provide a comprehensive, unbiased description of changes to cells caused by viral infection, but interpretation may be complicated by differential changes in infected and uninfected ‘bystander’ cells
Externí odkaz: https://doaj.org/article/ebbb57c2f26649a4b38fb103c69777b6
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10
Akademický článek
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