Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Wicke, Karsten"'
Autor:
Cassar, Steven, Breidenbach, Laura, Olson, Amanda, Huang, Xin, Britton, Heather, Woody, Clarissa, Sancheti, Pankajkumar, Stolarik, DeAnne, Wicke, Karsten, Hempel, Katja, LeRoy, Bruce
Publikováno v:
In Journal of Pharmacological and Toxicological Methods November 2017 88 Part 1:56-63
Autor:
Bespalov, Anton Y., van Gaalen, Marcel M., Sukhotina, Irina A., Wicke, Karsten, Mezler, Mario, Schoemaker, Hans, Gross, Gerhard
Publikováno v:
In European Journal of Pharmacology 2008 592(1):96-102
Autor:
Harri Rahn, Tina Zimmermann, Wicke Karsten, Georg C. Terstappen, Christopher Untucht, Stapf Marcus, Axel Meyer, Dong Ye, Michael Rohe, Heiko Manninga, Sergey Sotnikov, Victoria Demina, Mario Mezler, Christian L. Ried
Publikováno v:
Nanoscale advances. 3(9)
Hollow viral vectors, such as John Cunningham virus-like particles (JC VLPs), provide a unique opportunity to deliver drug cargo into targeted cells and tissue. Current understanding of the entry of JC virus in brain cells has remained insufficient.
Akademický článek
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Autor:
Wilfried Hornberger, Achim Moeller, Yanbin Lao, Kennan C. Marsh, Karla Drescher, Wicke Karsten, Andreas Kling, Ana Lucia Relo, Volker Nimmrich, Charles W. Hutchins, Katja Jantos, Helmut Mack
Publikováno v:
Journal of Medicinal Chemistry. 60:7123-7138
Calpain overactivation has been implicated in a variety of pathological disorders including ischemia/reperfusion injury, cataract formation, and neurodegenerative diseases such as Alzheimer's disease (AD). Herein we describe our efforts leading to th
Publikováno v:
Good Research Practice in Non-Clinical Pharmacology and Biomedicine ISBN: 9783030336554
Good Research Practice in Non-Clinical Pharmacology and Biomedicine
Handbook of Experimental Pharmacology
Handbook of Experimental Pharmacology-Good Research Practice in Non-Clinical Pharmacology and Biomedicine
Good Research Practice in Non-Clinical Pharmacology and Biomedicine
Handbook of Experimental Pharmacology
Handbook of Experimental Pharmacology-Good Research Practice in Non-Clinical Pharmacology and Biomedicine
Most, if not all, guidelines, recommendations, and other texts on Good Research Practice emphasize the importance of blinding and randomization. There is, however, very limited specific guidance on when and how to apply blinding and randomization. Th
Autor:
Wicke, Karsten, Garcia-Ladona, Javier *
Publikováno v:
In European Journal of Pharmacology 2001 424(2):85-90
Autor:
Wicke, Karsten M.1 karsten.wicke@abbott.com, Rex, Andre2, Jongen-Relo, Ana1, Groth, Ilona1, Gross, Gerhard1
Publikováno v:
Psychopharmacology. Nov2007, Vol. 195 Issue 1, p95-102. 8p. 1 Diagram, 9 Graphs.
Autor:
Wicke Karsten, Volker Nimmrich, David Hermann, Claus Bruehl, Andreas Draguhn, Mario Mezler, Michaela K. Müller, Gerhard Gross
Publikováno v:
European Journal of Pharmacology. 702:44-55
Alzheimer's disease is accompanied by increased brain levels of soluble amyloid-β (Aβ) oligomers. It has been suggested that oligomers directly impair synaptic function, thereby causing cognitive deficits in Alzheimer's disease patients. Recently,
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 386:155-166
The potential of D3 receptor antagonism to treat positive, negative, and cognitive symptoms of schizophrenia is reviewed on the basis of preclinical results and preliminary clinical data. Dopamine D3 receptors are expressed in mesencephalic, limbic,