Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Wibke Bechtel-Walz"'
Autor:
Haihua Guo, Manuel Rogg, Julia Keller, Ann-Kathrin Scherzinger, Julia Jäckel, Charlotte Meyer, Alena Sammarco, Martin Helmstädter, Oliver Gorka, Olaf Groß, Christoph Schell, Wibke Bechtel-Walz
Publikováno v:
Antioxidants, Vol 13, Iss 1, p 81 (2024)
(1) Background: Differentiated podocytes are particularly vulnerable to oxidative stress and cellular waste products. The disease-related loss of postmitotic podocytes is a direct indicator of renal disease progression and aging. Podocytes use highly
Externí odkaz:
https://doaj.org/article/9d0e7c481d1746ec910e91b95688da91
Autor:
Ellen Gebauer, Wibke Bechtel-Walz, Christoph Schell, Michelle Erbel, Gerd Walz, Tobias Hermle
Publikováno v:
Case Reports in Nephrology and Dialysis, Vol 11, Iss 3, Pp 270-274 (2021)
Immunotherapy using immune checkpoint inhibitors revolutionized therapies for a variety of malignancies. Nivolumab, an antibody blocking programmed cell death 1 protein, and ipilimumab that blocks cytotoxic T-lymphocyte-associated protein 4 effective
Externí odkaz:
https://doaj.org/article/30ba350cb1104f398d457bf92ed14587
Autor:
Björn Tampe, Desiree Tampe, Elisabeth M. Zeisberg, Gerhard A. Müller, Wibke Bechtel-Walz, Michael Koziolek, Raghu Kalluri, Michael Zeisberg
Publikováno v:
EBioMedicine, Vol 2, Iss 1, Pp 19-36 (2015)
Progression of chronic kidney disease remains a principal problem in clinical nephrology and there is a pressing need for novel therapeutics and biomarkers. Aberrant promoter CpG island methylation and subsequent transcriptional silencing of specific
Externí odkaz:
https://doaj.org/article/500fe40de07f4144b5b2f7b4768ad0ed
Autor:
Esther Nkuipou-Kenfack, Joost P Schanstra, Seerat Bajwa, Martin Pejchinovski, Claire Vinel, Cédric Dray, Philippe Valet, Jean-Loup Bascands, Antonia Vlahou, Thomas Koeck, Melanie Borries, Hauke Busch, Wibke Bechtel-Walz, Tobias B Huber, Karl L Rudolph, Andreas Pich, Harald Mischak, Petra Zürbig
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0166875 (2017)
Ageing is a complex process characterised by a systemic and progressive deterioration of biological functions. As ageing is associated with an increased prevalence of age-related chronic disorders, understanding its underlying molecular mechanisms ca
Externí odkaz:
https://doaj.org/article/eac3adf9042747e2a2439c4936619bea
Autor:
Markus M. Rinschen, Jennifer L. Harder, Madalina E. Carter-Timofte, Luis Zanon Rodriguez, Carmen Mirabelli, Fatih Demir, Naziia Kurmasheva, Suresh K. Ramakrishnan, Madlen Kunke, Yifan Tan, Anja Billing, Eileen Dahlke, Alexey A. Larionov, Wibke Bechtel-Walz, Ute Aukschun, Marlen Grabbe, Rikke Nielsen, Erik I. Christensen, Matthias Kretzler, Tobias B. Huber, Christiane E. Wobus, David Olagnier, Gary Siuzdak, Florian Grahammer, Franziska Theilig
Publikováno v:
Rinschen, M M, Harder, J L, Carter-Timofte, M E, Zanon Rodriguez, L, Mirabelli, C, Demir, F, Kurmasheva, N, Ramakrishnan, S K, Kunke, M, Tan, Y, Billing, A, Dahlke, E, Larionov, A A, Bechtel-Walz, W, Aukschun, U, Grabbe, M, Nielsen, R, Christensen, E I, Kretzler, M, Huber, T B, Wobus, C E, Olagnier, D, Siuzdak, G, Grahammer, F & Theilig, F 2022, ' VPS34-dependent control of apical membrane function of proximal tubule cells and nutrient recovery by the kidney ', Science Signaling, vol. 15, no. 762, pp. eabo7940 . https://doi.org/10.1126/scisignal.abo7940
The lipid kinase VPS34 orchestrates autophagy, endocytosis, and metabolism and is implicated in cancer and metabolic disease. The proximal tubule in the kidney is a key metabolic organ that controls reabsorption of nutrients such as fatty acids, amin
Autor:
Wibke Bechtel-Walz, Gerd Walz, Christoph Schell, Michelle Erbel, Ellen Gebauer, Tobias Hermle
Publikováno v:
Case Reports in Nephrology and Dialysis
Case reports in nephrology and dialysis, 11(3):270-274
Case Reports in Nephrology and Dialysis, Vol 11, Iss 3, Pp 270-274 (2021)
Case reports in nephrology and dialysis, 11(3):270-274
Case Reports in Nephrology and Dialysis, Vol 11, Iss 3, Pp 270-274 (2021)
Immunotherapy using immune checkpoint inhibitors revolutionized therapies for a variety of malignancies. Nivolumab, an antibody blocking programmed cell death 1 protein, and ipilimumab that blocks cytotoxic T-lymphocyte-associated protein 4 effective
Autor:
Wibke Bechtel-Walz, Nicola Wanner
Publikováno v:
Cell and Tissue Research. 369:75-92
DNA methylation and histone modifications determine renal programming and the development and progression of renal disease. The identification of the way in which the renal cell epigenome is altered by environmental modifiers driving the onset and pr
Autor:
Désirée Tampe, Raghu Kalluri, Wibke Bechtel-Walz, Elisabeth M. Zeisberg, Gerhard A. Müller, Michael Koziolek, Björn Tampe, Michael Zeisberg
Publikováno v:
EBioMedicine, Vol 2, Iss 1, Pp 19-36 (2015)
EBioMedicine
EBioMedicine
Progression of chronic kidney disease remains a principal problem in clinical nephrology and there is a pressing need for novel therapeutics and biomarkers. Aberrant promoter CpG island methylation and subsequent transcriptional silencing of specific
Autor:
Cédric Dray, Philippe Valet, Esther Nkuipou-Kenfack, Joost P. Schanstra, Karl Lenhard Rudolph, Thomas Koeck, Jean-Loup Bascands, Martin Pejchinovski, Harald Mischak, Tobias B. Huber, Hauke Busch, Melanie Börries, Wibke Bechtel-Walz, Andreas Pich, Antonia Vlahou, Petra Zürbig, Claire Vinel, Seerat Bajwa
Publikováno v:
PLOS ONE, 12(2):e0166875
PLoS ONE
PLoS ONE, Vol 12, Iss 2, p e0166875 (2017)
PLoS ONE
PLoS ONE, Vol 12, Iss 2, p e0166875 (2017)
Ageing is a complex process characterised by a systemic and progressive deterioration of biological functions. As ageing is associated with an increased prevalence of age-related chronic disorders, understanding its underlying molecular mechanisms ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db6ccde636d93ff8535d27a5538ea821
https://eprints.gla.ac.uk/137045/1/137045.pdf
https://eprints.gla.ac.uk/137045/1/137045.pdf
Autor:
Wibke Bechtel-Walz, Tobias B. Huber
Publikováno v:
Cell and Tissue Research. 356:601-608
Epigenetic mechanisms are fundamental key features of developing cells connecting developmental regulatory factors to chromatin modification. Changes in the environment during renal development can have long-lasting effects on the permanent tissue st