Validation of diffusion tensor MRI measurements of cardiac microstructure with structure tensor synchrotron radiation imaging

Autor: Teh, Irvin, McClymont, Darryl, Zdora, Marie-Christine, Whittington, Hannah J., Davidoiu, Valentina, Lee, Jack, Lygate, Craig A., Rau, Christoph, Zanette, Irene, Schneider, Jürgen E.

Publikováno v: In Journal of Cardiovascular Magnetic Resonance 5 December 2016 19(1)

Increasing creatine kinase activity protects against hypoxia / reoxygenation injury but not against anthracycline toxicity in vitro.

Autor: Zervou, Sevasti¹ szervou@well.ox.ac.uk, Whittington, Hannah J.¹, Ostrowski, Philip J.¹, Cao, Fang¹, Tyler, Jack¹, Lake, Hannah A.¹, Neubauer, Stefan¹, Lygate, Craig A.¹

Publikováno v: PLoS ONE. 8/14/2017, Vol. 12 Issue 8, p1-14. 14p.

Impaired cardiac contractile function in arginine:glycine amidinotransferase knockout mice devoid of creatine is rescued by homoarginine but not creatine

Autor: Faller, Kiterie M E, Atzler, Dorothee, McAndrew, Debra J, Zervou, Sevasti, Whittington, Hannah J, Simon, Jillian N, Aksentijevic, Dunja, Hove, Michiel Ten, Choe, Chi-Un, Isbrandt, Dirk, Casadei, Barbara, Schneider, Jurgen E, Neubauer, Stefan, Lygate, Craig A

Publikováno v: Cardiovascular Research
Cardiovascular research 114(3), 417-430 (2017). doi:10.1093/cvr/cvx242
Faller, K M E, Atzler, D, McAndrew, D J, Zervou, S, Whittington, H J, Simon, J N, Aksentijevic, D, Hove, M T, Choe, C-U, Isbrandt, D, Casadei, B, Schneider, J E, Neubauer, S & Lygate, C A 2018, ' Impaired cardiac contractile function in arginine:glycine amidinotransferase knockout mice devoid of creatine is rescued by homoarginine but not creatine ', Cardiovascular Research, vol. 114, no. 3, pp. 417–430 . https://doi.org/10.1093/cvr/cvx242

Aims: Creatine buffers cellular ATP via the creatine kinase reaction. Creatine levels are reduced in heart failure, but their contribution to pathophysiology is unclear. Arginine:glycine amidinotransferase (AGAT) in the kidney catalyses both the firs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5ade5982fdc47a2fda05b07b4ea7f627
http://europepmc.org/articles/PMC5982714

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The Diabetic Heart: Too Sweet for Its Own Good?

Autor: Whittington, Hannah J.¹, Babu, Girish G.¹, Mocanu, Mihaela M.¹, Yellon, Derek M.¹, Hausenloy, Derek J.¹ d.hausenloy@ucl.ac.uk

Publikováno v: Cardiology Research & Practice. 2012, p1-15. 15p. 4 Diagrams, 3 Charts.