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Autor:
Martin Lechmann, Birgit Essig, Mario Perro, Ulrike Hopfer, Harald Dürr, Peter Brünker, Leo Kunz, Moritz Rapp, Anne Freimoser-Grundschober, Thomas Emrich, Birte Appelt, Christine Trumpfheller, Anna Maria Giusti, Whitney Shannon Jordaan, Sara Labiano, Felix C. Weber, Elena Menietti, Eva Sum, Pablo Umana, Andrzej Sobieniecki, Marine Le Clech, Philipp Fröbel, Francois Christen, Dario Speziale, Nicolini Valeria G, Roberto Adelfio, Pedro Romero
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 27(14)
Purpose: CD40 agonists hold great promise for cancer immunotherapy (CIT) as they enhance dendritic cell (DC) activation and concomitant tumor-specific T-cell priming. However, the broad expression of CD40 accounts for sink and side effects, hampering