Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Whitney S. Irvin"'
Autor:
Suzanne Sullivan, Mark D. Handschumacher, Philipp E. Bartko, J. Luis Guerrero, Jill Wylie-Sears, Margo M. Seybolt, Whitney S. Irvin, Dae-Hee Kim, Catherine Szymanski, Robert A. Levine, Elena Aikawa, Albert Hagège, Joyce Bischoff, Michael L. Garcia, Emmanuel Messas, Jonathan Beaudoin, Jacob P. Dal-Bianco, Alain Carpentier, James S. Titus
After myocardial infarction (MI), mitral valve (MV) tethering stimulates adaptive leaflet growth, but counterproductive leaflet thickening and fibrosis augment mitral regurgitation (MR), doubling heart failure and mortality. MV fibrosis post-MI is as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7786271082081710c01a8c19773d9d12
https://europepmc.org/articles/PMC5679094/
https://europepmc.org/articles/PMC5679094/
Autor:
Jonathan Beaudoin, Robert A. Levine, Guillem Casanovas, Brittan Morris, Philipp E. Bartko, Margo M. Seybolt, Whitney S. Irvin, Joyce Bischoff, Michael L. Garcia, Elena Aikawa, Dae-Hee Kim, Suzanne Sullivan, Jacob P. Dal-Bianco, Joshua Keegan, Jill Wylie-Sears, J. Luis Guerrero
Rationale : Ischemic mitral regurgitation, a complication after myocardial infarction (MI), induces adaptive mitral valve (MV) responses that may be initially beneficial but eventually lead to leaflet fibrosis and MV dysfunction. We sought to examine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0cda9b614482ae0b227090cbcd0a2e9
https://europepmc.org/articles/PMC5215059/
https://europepmc.org/articles/PMC5215059/
Autor:
Joshua D. Hutcheson, Carlijn V. C. Bouten, Whitney S. Irvin, Elena Aikawa, Eduardo Martínez-Martínez, Sergio Bertazzo, Jona B. Krohn, MP Michelle Bendeck
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology, 36(3), 525-533. Lippincott Williams and Wilkins Ltd.
Objective— Collagen accumulation and calcification are major determinants of atherosclerotic plaque stability. Extracellular vesicle (EV)–derived microcalcifications in the collagen-poor fibrous cap may promote plaque rupture. In this study, we h
Autor:
Margo M. Seybolt, Philipp E. Bartko, Suzanne Sullivan, Mark D. Handschumacher, Jonathan Beaudoin, Miguel Chaput, Jacob P. Dal-Bianco, Emmanuel Messas, Michael L. Garcia, Whitney S. Irvin, J. Luis Guerrero, Albert Hagège, Joyce Bischoff, Robert A. Levine, Elena Aikawa, Catherine Szymanski, Jesper Hjortnaes, Jill Wylie-Sears, Alain Carpentier, Adam Mauskapf, James S. Titus
Publikováno v:
Journal of the American College of Cardiology, 67(3), 275. Elsevier USA
BACKGROUND: In patients with myocardial infarction (MI), leaflet tethering by displaced papillary muscles induces mitral regurgitation (MR), which doubles mortality. Mitral valves (MVs) are larger in such patients but fibrosis sets in counterproducti