Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Whitney R. Baldwin"'
Autor:
Camilo J. Acosta, Francesco Nordio, David A. Boltz, Whitney R. Baldwin, Greg Hather, Eloi Kpamegan
Publikováno v:
Microorganisms, Vol 12, Iss 6, p 1177 (2024)
A traditional phase 3 clinical efficacy study for a Zika vaccine may be unfeasible because of the current low transmission of Zika virus (ZIKV). An alternative clinical development approach to evaluate Zika vaccine efficacy (VE) is therefore required
Externí odkaz:
https://doaj.org/article/9bdd98c738f1404ab622ff8754bcf668
Autor:
Whitney R. Baldwin, Holli A. Giebler, Janae L. Stovall, Ginger Young, Kelly J. Bohning, Hansi J. Dean, Jill A. Livengood, Claire Y.-H. Huang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Here the authors generate a live-attenuated Zika vaccine based on a clinically proven dengue virus serotype-2 vaccine backbone and show that one dose protects mice and non-human primates from Zika virus infection.
Externí odkaz:
https://doaj.org/article/b8778b7cdf1e454aa4f4bbc9276e3404
Autor:
Camilo J Acosta, Clemente Diaz, Francesco Nordio, Htay-Htay Han, Kelley J Moss, Kelly Bohning, Pradeep Kumar, Mengya Liu, Hetal Patel, Filippo Pacciarini, Vincent Mwangi, Elke Walter, Tim D Powell, Hana M El Sahly, Whitney R Baldwin, Joseph Santangelo, Evan J Anderson, Gary Dubin
Publikováno v:
The Journal of infectious diseases.
Background We report 2-year persistence of immune response to Takeda's prophylactic purified formalin-inactivated whole Zika virus vaccine candidate (TAK-426) compared with that observed after natural infection. Methods A randomized, observer-blind,