Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Whitney R Smith-Kinnaman"'
Autor:
Jose F Victorino, Melanie J Fox, Whitney R Smith-Kinnaman, Sarah A Peck Justice, Katlyn H Burriss, Asha K Boyd, Megan A Zimmerly, Rachel R Chan, Gerald O Hunter, Yunlong Liu, Amber L Mosley
Publikováno v:
PLoS Genetics, Vol 16, Iss 3, p e1008317 (2020)
RNA Polymerase II (RNAPII) transcription termination is regulated by the phosphorylation status of the C-terminal domain (CTD). The phosphatase Rtr1 has been shown to regulate serine 5 phosphorylation on the CTD; however, its role in the regulation o
Externí odkaz:
https://doaj.org/article/8f0ee5c939f841e3a3a5a87eb92adaaa
Publikováno v:
PLoS Genetics, Vol 11, Iss 2, p e1004999 (2015)
The exosome and its nuclear specific subunit Rrp6 form a 3'-5' exonuclease complex that regulates diverse aspects of RNA biology including 3' end processing and degradation of a variety of noncoding RNAs (ncRNAs) and unstable transcripts. Known targe
Externí odkaz:
https://doaj.org/article/b8d26a25fa6b452f97067a853cd6813e
Autor:
Christine A. Berryhill, Emma H. Doud, Jocelyne N. Hanquier, Whitney R. Smith-Kinnaman, Devon L. McCourry, Amber L. Mosley, Evan M. Cornett
Publikováno v:
Biomolecules, Vol 14, Iss 7, p 817 (2024)
DZNep (3-deazaneplanocin A) is commonly used to reduce lysine methylation. DZNep inhibits S-adenosyl-l-homocysteine hydrolase (AHCY), preventing the conversion of S-adenosyl-l-homocysteine (SAH) into L-homocysteine. As a result, the SAM-to-SAH ratio
Externí odkaz:
https://doaj.org/article/3affc577ee8d49dc8c5f0c2dd1b4fb8b
Autor:
Amber L. Mosley, Phoebe A Nguyen, Cody M. Rogers, Whitney R. Smith-Kinnaman, Elsbeth Sanders, Matthew L. Bochman
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 12, Pp 4347-4357 (2020)
G3: Genes|Genomes|Genetics
G3: Genes|Genomes|Genetics
The human genome encodes five RecQ helicases (RECQL1, BLM, WRN, RECQL4, and RECQL5) that participate in various processes underpinning genomic stability. Of these enzymes, the disease-associated RECQL4 is comparatively understudied due to a variety o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f523e9aad0615fc054a65f06fcaa752
https://doi.org/10.1534/g3.120.401864
https://doi.org/10.1534/g3.120.401864
Autor:
Rachel R. Chan, Jose F. Victorino, Whitney R. Smith-Kinnaman, Asha K. Boyd, Megan A. Zimmerly, Gerald O. Hunter, Yunlong Liu, Hongyu Gao, Amber L. Mosley, Melanie J. Fox, Sarah A. Peck Justice
RNA Polymerase II (RNAPII) transcription termination is regulated by the phosphorylation status of the C-terminal domain (CTD). Using disruption-compensation (DisCo) protein-protein interaction network analysis, interaction changes were observed with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b9286b6777cb73068c1d88c3e9bf12
Autor:
Gerald O. Hunter, Sarah A. Peck Justice, Asha K. Boyd, Melanie J. Fox, Amber L. Mosley, Rachel R. Chan, Katlyn Hughes Burriss, Whitney R. Smith-Kinnaman, Megan A. Zimmerly, Jose F. Victorino, Yunlong Liu
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 16, Iss 3, p e1008317 (2020)
PLoS Genetics, Vol 16, Iss 3, p e1008317 (2020)
RNA Polymerase II (RNAPII) transcription termination is regulated by the phosphorylation status of the C-terminal domain (CTD). The phosphatase Rtr1 has been shown to regulate serine 5 phosphorylation on the CTD; however, its role in the regulation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1ca3b799b30962cd02a2f42c9c56e9c
https://pubmed.ncbi.nlm.nih.gov/32187185
https://pubmed.ncbi.nlm.nih.gov/32187185
Autor:
Zachary Golay, Lynn Glowczewski Bedard, Amber L. Mosley, Whitney R. Smith-Kinnaman, Nada Alakhras, Asha K. Boyd, Nichole Dyer
Publikováno v:
The FASEB Journal. 31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbcf4f946c8242bbf88551d0902d4d00
https://doi.org/10.1096/fasebj.31.1_supplement.752.8
https://doi.org/10.1096/fasebj.31.1_supplement.752.8
Autor:
Amber L. Mosley, Wen Yang, Peter L. Hsu, Fan Yang, Jae Eun Song, Gabriele Varani, Whitney R. Smith-Kinnaman
Publikováno v:
Journal of Molecular Biology. 426:2970-2981
The phosphorylation state of heptapeptide repeats within the C-terminal domain (CTD) of the largest subunit of RNA Polymerase II (PolII) controls the transcription cycle and is maintained by the competing action of kinases and phosphatases. Rtr1 was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::177e24c9ff4dbc3d579fbd8ca9ce2dbc
https://doi.org/10.1016/j.jmb.2014.06.010
https://doi.org/10.1016/j.jmb.2014.06.010
Autor:
Gabriele Varani, Jason D. True, Whitney R. Smith-Kinnaman, Gabriela I. Cabello, Peter L. Hsu, Melanie J. Fox, Gerald O. Hunter, Michael J. Berna, Amber L. Mosley
Publikováno v:
Mol. BioSyst.. 10:1730-1741
The phosphatase Rtr1 has been implicated in dephosphorylation of the RNA Polymerase II (RNAPII) C-terminal domain (CTD) during transcription elongation and in regulation of nuclear import of RNAPII. Although it has been shown that Rtr1 interacts with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3fc2b881e2904467dedb6151b3c649c
https://doi.org/10.1039/c4mb00109e
https://doi.org/10.1039/c4mb00109e
Autor:
Gerald O. Hunter, Amber L. Mosley, Madelaine Gogol, Whitney R. Smith-Kinnaman, Melanie J. Fox, Brian Fleharty
In eukaryotes, the C-terminal domain (CTD) of Rpb1 contains a heptapeptide repeat sequence of (Y1S2P3T4S5P6S7)n that undergoes reversible phosphorylation through the opposing action of kinases and phosphatases. Rtr1 is a conserved protein that coloca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37c7b0fda0b0b970aa440fff83453912
https://europepmc.org/articles/PMC4985930/
https://europepmc.org/articles/PMC4985930/