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pro vyhledávání: '"Whitney Purtha"'
Autor:
Yue Hao, Whitney Purtha, Christa Cortesio, Huan Rui, Yan Gu, Hao Chen, E Allen Sickmier, Paolo Manzanillo, Xin Huang
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200374 (2018)
Cathepsin H is a member of the papain superfamily of lysosomal cysteine proteases. It is the only known aminopeptidase in the family and is reported to be involved in cancer and other major diseases. Like many other proteases, it is synthesized as an
Externí odkaz:
https://doaj.org/article/bc889651b61041d4af51369ee8d2fabc
Autor:
Shen Dong, Daqi Xu, Jennifer Anne Bridge, Whitney Purtha, Allyson Spence, Danny Wells, Xiao hua Wang, Qizhi Tang, Mark S. Anderson, Jeffrey A. Bluestone
Publikováno v:
The Journal of Immunology. 200:101.12-101.12
Antigen specific Tregs are more efficient than polyclonal Tregs in their suppressive capacity, which makes them attractive tools for further targeted tolerogenic therapy. Autoreactive T cells specificity has been well characterized in type 1-diabetes
Publikováno v:
The Journal of Immunology. 186:105.16-105.16
Memory B cells (MBC) and long-lived plasma cells (LLPC) are generated after infection, but the significance of each population in conferring protection against secondary challenge remains unclear. Using a mouse model of West Nile virus (WNV) infectio