Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Whitney M. Nolte"'
Publikováno v:
Med Chem Res
Modification of endogenous proteins by drugs and drug metabolites are thought to be a cause of idiosyncratic adverse drug reactions (IADRs). Trimethoprim (TMP) is a commonly prescribed antibiotic that has been implicated in IADRs; however, there is n
Publikováno v:
Drug Metabolism and Pharmacokinetics. 35:S74
Autor:
Whitney M. Nolte, Philip A. Carpino
Publikováno v:
Allosterism in Drug Discovery ISBN: 9781782624592
Positive allosteric modulators (PAMs) of G-protein-coupled receptors (GPCRs) potentiate the activity of ligands that act at orthosteric sites on the receptors. While the majority of GPCR PAMs bind reversibly to allosteric sites on receptors to induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82d1e350e8d776d54ca049e4db8b2a46
https://doi.org/10.1039/9781782629276-00271
https://doi.org/10.1039/9781782629276-00271
Publikováno v:
Annual Review of Immunology. 30:611-646
Stressors ranging from nutrient deprivation to immune signaling can induce the degradation of cytoplasmic material by a process known as autophagy. Increasingly, research on autophagy has begun to focus on its role in inflammation and the immune resp
Publikováno v:
The AAPS Journal. 12:483-491
The prolyl peptidases are a family of enzymes characterized by a biochemical preference for cleaving proline-containing peptides. The members of this enzyme family include prolyl endopeptidase, prolyl endopeptidase-like, dipeptidyl peptidase 4 (DPP4)
Publikováno v:
Chemistry of Materials. 21:442-446
A diazonium salt-derived organoimido hexamolybdate was synthesized and directly covalently immobilized on Si surfaces using diazonium chemistry to form both monolayers and multilayers. These monolayers and multilayers were characterized by ellipsomet
Autor:
Whitney M. Nolte
Publikováno v:
The FASEB Journal. 29
Autor:
Jianli He, James M. Tour, Harry Pang, William F Reus, David P. Nackashi, Bo Chen, Whitney M. Nolte, Paul D. Franzon, Meng Lu, Tao He
Publikováno v:
Journal of the American Chemical Society. 128:14537-14541
We have controllably modulated the drain current (I(D)) and threshold voltage (V(T)) in pseudo metal-oxide-semiconductor field-effect transistors (MOSFETs) by grafting a monolayer of molecules atop oxide-free H-passivated silicon surfaces. An electro
Autor:
Rajeev K. Wahi, Whitney M. Nolte, Yunping Liu, Michelle L. Mejia, William W. Yu, Vicki L. Colvin, Joshua C. Falkner
Publikováno v:
Journal of Molecular Catalysis A: Chemical. 242:48-56
The effects of various physical properties (particle size, shape, surface area, crystal structure, and phase composition) on the photocatalytic performance of nanosized TiO2 were studied through the photodegradation of Congo Red. Kinetic results show
Autor:
David Price, Heather Eng, David A. Griffith, Whitney M. Nolte, Raman Sharma, Thomas S. McDonald, Benjamin D. Stevens, Chris Limberakis, Margaret Jackson, Xianping Li, David J. Edmonds, Jean-Phillippe Fortin, Amit S. Kalgutkar
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 41(8)
4-(3-(Benzyloxy)phenyl)-2-(ethylsulfinyl)-6-(trifluoromethyl)pyrimidine (BETP) represents a novel small-molecule activator of the glucagon-like peptide-1 receptor (GLP-1R), and exhibits glucose-dependent insulin secretion in rats following i.v. (but