Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Whitney Franklin"'
Autor:
Ali Bootwala, Hyun Hwan An, Meghan Whitney Franklin, Benjamin J. Manning, Lucy Y. Xu, Shruti Panchal, Joseph D. Garlick, Reshica Baral, Michael E. Hudson, Gevorg Grigoryan, Mark A. Murakami, Kristen Hopson, Daniel S. Leventhal
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The optimal use of many biotherapeutics is restricted by Anti-drug antibodies (ADAs) and hypersensitivity responses which can affect potency and ability to administer a treatment. Here we demonstrate that Re-surfacing can be utilized as a generalizab
Externí odkaz:
https://doaj.org/article/4a3b4c9302ed43f8bcb616f28001d45c
Autor:
Maria-Adelaide Micci, Balaji Krishnan, Elizabeth Bishop, Wen-Ru Zhang, Jutatip Guptarak, Auston Grant, Olga Zolochevska, Batbayar Tumurbaatar, Whitney Franklin, Claudia Marino, Steven G. Widen, Arjun Luthra, Steven G. Kernie, Giulio Taglialatela
Publikováno v:
Molecular Neurodegeneration, Vol 14, Iss 1, Pp 1-22 (2019)
Abstract Background Adult hippocampal neurogenesis plays an important role in synaptic plasticity and cogntive function. We reported that higher numbers of neural stem cells (NSC) in the hippocampus of cognitively-intact individuals with high Alzheim
Externí odkaz:
https://doaj.org/article/558165347ed14f368a584933fe424384
Autor:
Meghan Whitney Franklin, Sergey Nepomnyachyi, Ryan Feehan, Nir Ben-Tal, Rachel Kolodny, Joanna SG Slusky
Publikováno v:
eLife, Vol 7 (2018)
Outer membrane proteins (OMPs) are the proteins in the surface of Gram-negative bacteria. These proteins have diverse functions but a single topology: the β-barrel. Sequence analysis has suggested that this common fold is a β-hairpin repeat protein
Externí odkaz:
https://doaj.org/article/69259f8ebb4d4194a9db6262707ed056
Autor:
Fady Baky, Yair Lotan, Tolulope Bakare, Whitney Franklin, Steve Hudak, Jessica Mears, Solomon L. Woldu, Ryan Hutchinson, Brett A. Johnson, Kyle S. Ames, Andrew Barefoot, Jodi Antonelli, Patricia Magness, Jorge Sanchez, Somer Blair
Publikováno v:
Urology. 149:98-102
Objective To evaluate factors associated with simple nephrectomy at a safety net hospital with a diverse patient population and large catchment area. Simple nephrectomy is an underreported surgery. Performance of simple nephrectomy may represent a fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6490d2fef0478f642ae0c1e3636db7a3
https://doi.org/10.1016/j.urology.2020.12.013
https://doi.org/10.1016/j.urology.2020.12.013
Autor:
Steven G. Widen, Arjun Luthra, Steven G. Kernie, Wen Ru Zhang, Maria-Adelaide Micci, Jutatip Guptarak, Batbayar Tumurbaatar, Auston Cody Grant, Balaji Krishnan, Giulio Taglialatela, Olga Zolochevska, Elizabeth Bishop, Whitney Franklin, Claudia Marino
Publikováno v:
Molecular Neurodegeneration, Vol 14, Iss 1, Pp 1-22 (2019)
Molecular Neurodegeneration
Molecular Neurodegeneration
Background Adult hippocampal neurogenesis plays an important role in synaptic plasticity and cogntive function. We reported that higher numbers of neural stem cells (NSC) in the hippocampus of cognitively-intact individuals with high Alzheimer’s di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ece685cfa61341fdd3d912148ddf7ba
http://link.springer.com/article/10.1186/s13024-019-0322-8
http://link.springer.com/article/10.1186/s13024-019-0322-8
Outer membrane proteins are all beta barrels and these barrels have a variety of well-documented loop conformations. Here we test the effect of three different loop types on outer membrane protein A (OmpA) folding. We designed twelve 5-residue loops
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8a4da4d03474e0524dac9c09eb6ed38
https://doi.org/10.1101/2020.10.08.331546
https://doi.org/10.1101/2020.10.08.331546
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports
Scientific Reports
Traumatic brain injury (TBI) is a risk factor for Alzheimer’s disease (AD), although the mechanisms contributing to this increased risk are unknown. Insulin resistance is an additional risk factor for AD whereby decreased insulin signaling increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::777d90c857feb2867f2e21dd35e8ac50
https://doi.org/10.1038/s41598-019-44635-z
https://doi.org/10.1038/s41598-019-44635-z
Autor:
Holly M. Brown-Borg, Colin K. Combs, Kendra L. Puig, Whitney Franklin, Joshua A. Kulas, Giulio Taglialatela, Sharlene G. Rakoczy
Publikováno v:
Neurobiology of Aging. 40:22-40
APP/PS1 double transgenic mice expressing human mutant amyloid precursor protein (APP) and presenilin-1 (PS-1) demonstrate robust brain Aβ peptide containing plaque deposition, increased markers of oxidative stress, behavioral dysfunction, and proin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::979805e716a05e098c014403e67764c9
https://doi.org/10.1016/j.neurobiolaging.2015.12.021
https://doi.org/10.1016/j.neurobiolaging.2015.12.021
Autor:
Giulio Taglialatela, Whitney Franklin
Publikováno v:
Journal of Neuroscience Methods. 261:128-134
Background Studying the insulin signaling response at the synapse is an important approach to understand molecular mechanisms involved in disease-related neurodegenerative processes. New method We developed a method for studying the insulin responsiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::061857bd9f27bcf2f3107f1400f3fd0f
https://doi.org/10.1016/j.jneumeth.2016.01.006
https://doi.org/10.1016/j.jneumeth.2016.01.006
Autor:
Colin K. Combs, Rachel D. Hendrix, Steven W. Barger, Whitney Franklin, Kumi Nagamoto-Combs, Kendra L. Puig, Nicholas A. Smith, Joshua A. Kulas, Gunjan D. Manocha, Giulio Taglialatela
The amyloid precursor protein (APP) is a type I transmembrane glycoprotein widely studied for its role as the source of β-amyloid peptide, accumulation of which is causal in at least some cases of Alzheimer’s disease (AD). APP is expressed ubiquit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08839e879ebb8be57e8c1e561e25a3c8
https://europepmc.org/articles/PMC6417684/
https://europepmc.org/articles/PMC6417684/