Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Whitney E. Purtha"'
Autor:
Yue Hao, Whitney E Purtha, Christa Cortesio, Huan Rui, Yan Gu, Hao Chen, E Allen Sickmier, Paolo S Manzanillo, Xin Huang
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218063 (2019)
[This corrects the article DOI: 10.1371/journal.pone.0200374.].
Externí odkaz:
https://doaj.org/article/34fad8c3366b45b7b5552fa19e5be426
Autor:
Youmin Kim, Teague Sterling, Shen Dong, Chia-Hsin Ju, Allyson Spence, Mark S. Anderson, William H. Robinson, Qizhi Tang, Janice Tam, Jeffrey A. Bluestone, Maki Nakayama, Whitney E. Purtha
Publikováno v:
Proceedings of the National Academy of Sciences. 115:5265-5270
Regulatory T cells (Tregs) control organ-specific autoimmunity in a tissue antigen-specific manner, yet little is known about their specificity in a natural repertoire. In this study, we used the nonobese diabetic (NOD) mouse model of autoimmune diab
Autor:
Christa L. Cortesio, Paolo Manzanillo, Whitney E. Purtha, Hao Chen, E. Allen Sickmier, Yan Gu, Xin Huang, Yue Hao, Huan Rui
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218063 (2019)
[This corrects the article DOI: 10.1371/journal.pone.0200374.].
Autor:
Maki Nakayama, William H. Robinson, Qizhi Tang, Jeffrey A. Bluestone, Whitney E. Purtha, Janice Tam, Chia-Hsin Ju, Teague Sterling, Allyson Spence, Youmin Kim, Shen Dong, Mark S. Anderson
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 115, iss 24
Regulatory T cells (Tregs) control organ-specific autoimmunity in a tissue antigen-specific manner, yet little is known about their specificity in a natural repertoire. In this study, we used the nonobese diabetic (NOD) mouse model of autoimmune diab
Autor:
Whitney E. Purtha, Brian S. Kim, Mark S. Anderson, Emilie V. Russler-Germain, Mark A. Schroeder, Jaebok Choi, Takeshi Egawa, Matthew L. Cooper, You W. Zhou, Justin S. A. Perry, John F. DiPersio, Chyi-Song Hsieh, Byeong Chel Lee, Vanessa Salazar, Nada A. Abumrad
Publikováno v:
Immunity, vol 48, iss 5
Summary The development of T cell tolerance in the thymus requires the presentation of host proteins by multiple antigen-presenting cell (APC) types. However, the importance of transferring host antigens from transcription factor AIRE-dependent medul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b5f2d9066be1a1c3fc860967ed7cc7f
https://escholarship.org/uc/item/0dj15720
https://escholarship.org/uc/item/0dj15720
Autor:
E. Allen Sickmier, Paolo Manzanillo, Huan Rui, Whitney E. Purtha, Hao Chen, Yue Hao, Christa L. Cortesio, Yan Gu, Xin Huang
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 7, p e0200374 (2018)
PLoS ONE, Vol 13, Iss 7, p e0200374 (2018)
Cathepsin H is a member of the papain superfamily of lysosomal cysteine proteases. It is the only known aminopeptidase in the family and is reported to be involved in cancer and other major diseases. Like many other proteases, it is synthesized as an
Publikováno v:
Journal of Virology. 82:10964-10974
The B-cell response against West Nile virus (WNV), an encephaliticFlavivirusof global concern, is critical to controlling central nervous system dissemination and neurological sequelae, including death. Here, using a well-characterized mouse model of
Autor:
Hirokazu Matsushita, Robert D. Schreiber, Kenneth M. Murphy, Michael S. Diamond, Brian T. Edelson, Boris Calderon, Masako Kohyama, Whitney E. Purtha, Mark S Diamond, Theresa L. Murphy, Barbara U. Schraml, Kai Hildner, Emil R. Unanue
Publikováno v:
Science. 322:1097-1100
Although in vitro observations suggest that cross-presentation of antigens is mediated primarily by CD8α + dendritic cells, in vivo analysis has been hampered by the lack of systems that selectively eliminate this cell lineage. We show that deletion
Autor:
Gregory D. Gromowski, Alan D.T. Barrett, Daved H. Fremont, Grant E. Nybakken, S. Kyle Austin, Theodore Oliphant, Whitney E. Purtha, John T. Roehrig, Michael S. Diamond, Soila Sukupolvi-Petty, Jacob J. Schlesinger
Publikováno v:
Journal of Virology. 81:12816-12826
Neutralization of flaviviruses in vivo correlates with the development of an antibody response against the viral envelope (E) protein. Previous studies demonstrated that monoclonal antibodies (MAbs) against an epitope on the lateral ridge of domain I
Autor:
Daved H. Fremont, Vesselin Mitaksov, Janet M. Connolly, Elizabeth Sitati, Michael S. Diamond, Nancy B. Myers, Whitney E. Purtha, Ted H. Hansen
Publikováno v:
European Journal of Immunology. 37:1845-1854
Infection with West Nile virus (WNV) causes fatal encephalitis in immunocompromised animals. Previous studies in mice have established that T cell protection is required for clearance of WNV infection from tissues and preventing viral persistence. Th