ASCL1 represses a SOX9 ⁺ neural crest stem-like state in small cell lung cancer.

Autor: Olsen RR; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA., Ireland AS; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA., Kastner DW; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA., Groves SM; Department of Biochemistry, Vanderbilt University, Nashville, Tennessee 37212, USA., Spainhower KB; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA., Pozo K; Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA., Kelenis DP; Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA., Whitney CP; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA., Guthrie MR; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA., Wait SJ; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA., Soltero D; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA., Witt BL; Department of Pathology, University of Utah, Salt Lake City, Utah 84112, USA.; ARUP Laboratories at University of Utah, Salt Lake City, Utah 84108, USA., Quaranta V; Department of Biochemistry, Vanderbilt University, Nashville, Tennessee 37212, USA., Johnson JE; Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.; Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA., Oliver TG; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA.

Publikováno v: Genes & development [Genes Dev] 2021 Jun; Vol. 35 (11-12), pp. 847-869. Date of Electronic Publication: 2021 May 20.

MYC paralog-dependent apoptotic priming orchestrates a spectrum of vulnerabilities in small cell lung cancer.

Autor: Dammert MA; Molecular Pathology, Institute of Pathology, University Hospital of Cologne, 50937, Cologne, Germany.; Department of Translational Genomics, Center of Integrated Oncology Cologne-Bonn, Medical Faculty, University of Cologne, 50931, Cologne, Germany.; Center for Molecular Medicine Cologne, University of Cologne, 50931, Cologne, Germany., Brägelmann J; Molecular Pathology, Institute of Pathology, University Hospital of Cologne, 50937, Cologne, Germany.; Department of Translational Genomics, Center of Integrated Oncology Cologne-Bonn, Medical Faculty, University of Cologne, 50931, Cologne, Germany.; Center for Molecular Medicine Cologne, University of Cologne, 50931, Cologne, Germany.; Else Kröner Forschungskolleg Clonal Evolution in Cancer, University Hospital Cologne, 50931, Cologne, Germany., Olsen RR; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, 84112, USA., Böhm S; Department of Translational Genomics, Center of Integrated Oncology Cologne-Bonn, Medical Faculty, University of Cologne, 50931, Cologne, Germany.; Center for Molecular Medicine Cologne, University of Cologne, 50931, Cologne, Germany., Monhasery N; Molecular Pathology, Institute of Pathology, University Hospital of Cologne, 50937, Cologne, Germany.; Department of Translational Genomics, Center of Integrated Oncology Cologne-Bonn, Medical Faculty, University of Cologne, 50931, Cologne, Germany.; Center for Molecular Medicine Cologne, University of Cologne, 50931, Cologne, Germany., Whitney CP; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, 84112, USA., Chalishazar MD; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, 84112, USA., Tumbrink HL; Molecular Pathology, Institute of Pathology, University Hospital of Cologne, 50937, Cologne, Germany.; Department of Translational Genomics, Center of Integrated Oncology Cologne-Bonn, Medical Faculty, University of Cologne, 50931, Cologne, Germany.; Center for Molecular Medicine Cologne, University of Cologne, 50931, Cologne, Germany., Guthrie MR; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, 84112, USA., Klein S; Department of Translational Genomics, Center of Integrated Oncology Cologne-Bonn, Medical Faculty, University of Cologne, 50931, Cologne, Germany.; Center for Molecular Medicine Cologne, University of Cologne, 50931, Cologne, Germany.; Else Kröner Forschungskolleg Clonal Evolution in Cancer, University Hospital Cologne, 50931, Cologne, Germany.; Institute of Pathology, University Hospital of Cologne, 50937, Cologne, Germany., Ireland AS; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, 84112, USA., Ryan J; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, 02215, USA., Schmitt A; Department I of Internal Medicine, University Hospital of Cologne, 50931, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Response in Aging-Associated Diseases, University of Cologne, 50931, Cologne, Germany., Marx A; Molecular Pathology, Institute of Pathology, University Hospital of Cologne, 50937, Cologne, Germany.; Department of Translational Genomics, Center of Integrated Oncology Cologne-Bonn, Medical Faculty, University of Cologne, 50931, Cologne, Germany.; Center for Molecular Medicine Cologne, University of Cologne, 50931, Cologne, Germany., Ozretić L; Department of Cellular Pathology, Royal Free Hospital, London, NW3 2QG, UK., Castiglione R; Else Kröner Forschungskolleg Clonal Evolution in Cancer, University Hospital Cologne, 50931, Cologne, Germany.; Institute of Pathology, University Hospital of Cologne, 50937, Cologne, Germany., Lorenz C; Molecular Pathology, Institute of Pathology, University Hospital of Cologne, 50937, Cologne, Germany.; Department of Translational Genomics, Center of Integrated Oncology Cologne-Bonn, Medical Faculty, University of Cologne, 50931, Cologne, Germany.; Center for Molecular Medicine Cologne, University of Cologne, 50931, Cologne, Germany., Jachimowicz RD; Department I of Internal Medicine, University Hospital of Cologne, 50931, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Response in Aging-Associated Diseases, University of Cologne, 50931, Cologne, Germany., Wolf E; Theodor Boveri Institute, Biocenter, University of Würzburg, 97074, Würzburg, Germany., Thomas RK; Department of Translational Genomics, Center of Integrated Oncology Cologne-Bonn, Medical Faculty, University of Cologne, 50931, Cologne, Germany., Poirier JT; Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Büttner R; Institute of Pathology, University Hospital of Cologne, 50937, Cologne, Germany., Sen T; Department of Thoracic and Head & Neck Medical Oncology, University of Texas, MD Anderson Cancer Center, Houston, TX, 77030, USA., Byers LA; Department of Thoracic and Head & Neck Medical Oncology, University of Texas, MD Anderson Cancer Center, Houston, TX, 77030, USA., Reinhardt HC; Else Kröner Forschungskolleg Clonal Evolution in Cancer, University Hospital Cologne, 50931, Cologne, Germany.; Department I of Internal Medicine, University Hospital of Cologne, 50931, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Response in Aging-Associated Diseases, University of Cologne, 50931, Cologne, Germany., Letai A; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, 02215, USA., Oliver TG; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, 84112, USA. trudy.oliver@hci.utah.edu., Sos ML; Molecular Pathology, Institute of Pathology, University Hospital of Cologne, 50937, Cologne, Germany. martin.sos@uni-koeln.de.; Department of Translational Genomics, Center of Integrated Oncology Cologne-Bonn, Medical Faculty, University of Cologne, 50931, Cologne, Germany. martin.sos@uni-koeln.de.; Center for Molecular Medicine Cologne, University of Cologne, 50931, Cologne, Germany. martin.sos@uni-koeln.de.

Publikováno v: Nature communications [Nat Commun] 2019 Aug 02; Vol. 10 (1), pp. 3485. Date of Electronic Publication: 2019 Aug 02.

Epigenome-wide DNA methylation analysis of small cell lung cancer cell lines suggests potential chemotherapy targets.

Autor: Krushkal, Julia¹ (AUTHOR) julia.krushkal@nih.gov, Silvers, Thomas² (AUTHOR), Reinhold, William C.³ (AUTHOR), Sonkin, Dmitriy¹ (AUTHOR), Vural, Suleyman¹ (AUTHOR), Connelly, John² (AUTHOR), Varma, Sudhir³ (AUTHOR), Meltzer, Paul S.⁴ (AUTHOR), Kunkel, Mark⁵ (AUTHOR), Rapisarda, Annamaria² (AUTHOR), Evans, David² (AUTHOR), Pommier, Yves³ (AUTHOR), Teicher, Beverly A.⁶ (AUTHOR) Beverly.Teicher@nih.gov

Publikováno v: Clinical Epigenetics. 6/25/2020, Vol. 12 Issue 1, p1-28. 28p.

An Annotated Checklist of the Horse Flies, Deer Flies, and Yellow Flies (Diptera: Tabanidae) of Florida.

Autor: Nalen, Catherine M. Zettel¹, Kline, Daniel L.¹, Sutton, Bruce D.², Müller, Günter³, Cilek, James E.⁴

Publikováno v: Florida Entomologist (Florida Entomological Society). Jun2015, Vol. 98 Issue 2, p479-488. 10p.

Mechanisms of small cell lung cancer metastasis.

Autor: Ko, Julie, Winslow, Monte M, Sage, Julien

Publikováno v: EMBO Molecular Medicine; 1/11/2021, Vol. 13 Issue 1, p1-13, 13p