Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Whitney C. Weber"'
Autor:
Whitney C. Weber, Takeshi F. Andoh, Craig N. Kreklywich, Zachary J. Streblow, Michael Denton, Magdalene M. Streblow, John M. Powers, Gauthami Sulgey, Samuel Medica, Igor Dmitriev, David T. Curiel, Nicole N. Haese, Daniel N. Streblow
Publikováno v:
Vaccines, Vol 12, Iss 9, p 970 (2024)
Chikungunya virus (CHIKV) is a pathogenic arthritogenic alphavirus responsible for large-scale human epidemics for which a vaccine was recently approved for use. Mayaro virus (MAYV) is a related emerging alphavirus with epidemic potential with circul
Externí odkaz:
https://doaj.org/article/a5c3ecbf3e444fc38d200d6716b2545d
Autor:
Whitney C. Weber, Zachary J. Streblow, Craig N. Kreklywich, Michael Denton, Gauthami Sulgey, Magdalene M. Streblow, Dorca Marcano, Paola N. Flores, Rachel M. Rodriguez-Santiago, Luisa I. Alvarado, Vanessa Rivera-Amill, William B. Messer, Romana Hochreiter, Karin Kosulin, Katrin Dubischar, Vera Buerger, Daniel N. Streblow
Publikováno v:
Vaccines, Vol 12, Iss 8, p 893 (2024)
The first vaccine against chikungunya virus (CHIKV) was recently licensed in the U.S., Europe, and Canada (brand IXCHIQ®, referred to as VLA1553). Other pathogenic alphaviruses co-circulate with CHIKV and major questions remain regarding the potenti
Externí odkaz:
https://doaj.org/article/bffc37a281b04519b216184bce06b458
Autor:
Xiao L. Chang, Gabriela M. Webb, Helen L. Wu, Justin M. Greene, Shaheed Abdulhaqq, Katherine B. Bateman, Jason S. Reed, Cleiton Pessoa, Whitney C. Weber, Nicholas Maier, Glen M. Chew, Roxanne M. Gilbride, Lina Gao, Rebecca Agnor, Travis Giobbi, Jeffrey Torgerson, Don Siess, Nicole Burnett, Miranda Fischer, Oriene Shiel, Cassandra Moats, Bruce Patterson, Kush Dhody, Scott Kelly, Nader Pourhassan, Diogo M. Magnani, Jeremy Smedley, Benjamin N. Bimber, Nancy L. Haigwood, Scott G. Hansen, Timothy R. Brown, Lishomwa C. Ndhlovu, Jonah B. Sacha
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
CCR5 is a co-receptor for many transmitted HIV strains. Here, the authors show that biweekly injection of the CCR5-specific antibody Leronlimab protects rhesus macaques against infection following repeated intrarectal challenges of a CCR5-tropic SHIV
Externí odkaz:
https://doaj.org/article/e057d02dc1bf44278b9075dfe29c62e7
Autor:
Xiao L Chang, Jason S Reed, Gabriela M Webb, Helen L Wu, Jimmy Le, Katherine B Bateman, Justin M Greene, Cleiton Pessoa, Courtney Waytashek, Whitney C Weber, Joseph Hwang, Miranda Fischer, Cassandra Moats, Oriene Shiel, Rachele M Bochart, Hugh Crank, Don Siess, Travis Giobbi, Jeffrey Torgerson, Rebecca Agnor, Lina Gao, Kush Dhody, Jacob P Lalezari, Ivo Sah Bandar, Alnor M Carnate, Alina S Pang, Michael J Corley, Scott Kelly, Nader Pourhassan, Jeremy Smedley, Benjamin N Bimber, Scott G Hansen, Lishomwa C Ndhlovu, Jonah B Sacha
Publikováno v:
PLoS Pathogens, Vol 18, Iss 3, p e1010396 (2022)
The CCR5-specific antibody Leronlimab is being investigated as a novel immunotherapy that can suppress HIV replication with minimal side effects. Here we studied the virological and immunological consequences of Leronlimab in chronically CCR5-tropic
Externí odkaz:
https://doaj.org/article/e58ad860af654e17bfc075a249a3a48a
Autor:
Helen L. Wu, Kathleen Busman-Sahay, Whitney C. Weber, Courtney M. Waytashek, Carla D. Boyle, Katherine B. Bateman, Jason S. Reed, Joseph M. Hwang, Christine Shriver-Munsch, Tonya Swanson, Mina Northrup, Kimberly Armantrout, Heidi Price, Mitch Robertson-LeVay, Samantha Uttke, Mithra R. Kumar, Emily J. Fray, Sol Taylor-Brill, Stephen Bondoc, Rebecca Agnor, Stephanie L. Junell, Alfred W. Legasse, Cassandra Moats, Rachele M. Bochart, Joseph Sciurba, Benjamin N. Bimber, Michelle N. Sullivan, Brandy Dozier, Rhonda P. MacAllister, Theodore R. Hobbs, Lauren D. Martin, Angela Panoskaltsis-Mortari, Lois M.A. Colgin, Robert F. Siliciano, Janet D. Siliciano, Jacob D. Estes, Jeremy V. Smedley, Michael K. Axthelm, Gabrielle Meyers, Richard T. Maziarz, Benjamin J. Burwitz, Jeffrey J. Stanton, Jonah B. Sacha
Publikováno v:
Immunity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93b382225fa6efa51126f59c14a8877a
https://doi.org/10.1016/j.immuni.2023.04.019
https://doi.org/10.1016/j.immuni.2023.04.019
Autor:
Bruce K. Patterson, Whitney C. Weber, Gabriela M. Webb, Katherine B. Bateman, Cleiton Pessoa, Shaheed A. Abdulhaqq, Lina Gao, Benjamin N. Bimber, Jonah B. Sacha, Scott G. Hansen, Xiao L. Chang, Justin M. Greene, Kush Dhody, Scott Kelly, Nancy L. Haigwood, Rebecca Agnor, Cassandra Moats, Glen M. Chew, Roxanne M. Gilbride, Jeremy Smedley, Nicole D Burnett, Oriene Shiel, Nicholas Maier, Don Siess, Lishomwa C. Ndhlovu, Miranda Fischer, Timothy R. Brown, Diogo M. Magnani, Jason S. Reed, Travis Giobbi, Jeffrey Torgerson, Helen L. Wu, Nader Pourhassan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications
Nature Communications
In the absence of a prophylactic vaccine, the use of antiretroviral therapy (ART) as pre-exposure prophylaxis (PrEP) to prevent HIV acquisition by uninfected individuals is a promising approach to slowing the epidemic, but its efficacy is hampered by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e606e6b89376a17f5abd25dc4b8683a
https://doaj.org/article/e057d02dc1bf44278b9075dfe29c62e7
https://doaj.org/article/e057d02dc1bf44278b9075dfe29c62e7
Autor:
John M. Powers, Zoe L. Lyski, Whitney C. Weber, Michael Denton, Magdalene M. Streblow, Adam T. Mayo, Nicole N. Haese, Chad D. Nix, Rachel Rodríguez-Santiago, Luisa I. Alvarado, Vanessa Rivera-Amill, William B. Messer, Daniel N. Streblow
Publikováno v:
PLOS Neglected Tropical Diseases. 17:e0011154
Infections with Chikungunya virus, a mosquito-borne alphavirus, cause an acute febrile syndrome often followed by chronic arthritis that persists for months to years post-infection. Neutralizing antibodies are the primary immune correlate of protecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4781ada74742fb44400a2e1c2a622cab
https://doi.org/10.1371/journal.pntd.0011154
https://doi.org/10.1371/journal.pntd.0011154
Autor:
Alfred W. Legasse, Mina Northrup, Michael K. Axthelm, Tonya Swanson, Cassandra Moats, Whitney C. Weber, Jeremy Smedley, Kimberly Armantrout, Lauren D. Martin, Christine Shriver-Munsch, Helen L. Wu, Katherine B. Bateman, Justin M. Greene, Richard T. Maziarz, Benjamin J. Burwitz, Theodore R. Hobbs, Jonah B. Sacha, Nicholas Maier
Publikováno v:
J Clin Apher
Macaques are physiologically relevant animal models of human immunology and infectious disease that have provided key insights and advanced clinical treatment in transplantation, vaccinology, and HIV/AIDS. However, the small size of macaques is a stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d97e5ae17f9f8f47221816b8979ead0
https://doi.org/10.1002/jca.21842
https://doi.org/10.1002/jca.21842
Autor:
Dawn K. Slifka, Hans-Peter Raué, Whitney C. Weber, Takeshi F. Andoh, Craig N. Kreklywich, Victor R. DeFilippis, Daniel N. Streblow, Mark K. Slifka, Ian J. Amanna
Publikováno v:
PLoS pathogens. 18(7)
Chikungunya virus (CHIKV) is an emerging/re-emerging mosquito-borne pathogen responsible for explosive epidemics of febrile illness characterized by debilitating polyarthralgia and the risk of lethal infection among the most severe cases. Despite the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a481bfa48b1ea518b20a3609c250fff4
https://pubmed.ncbi.nlm.nih.gov/35788221
https://pubmed.ncbi.nlm.nih.gov/35788221
Autor:
Xiao L. Chang, Jason S. Reed, Gabriela M. Webb, Helen L. Wu, Jimmy Le, Katherine B. Bateman, Justin M. Greene, Cleiton Pessoa, Courtney Waytashek, Whitney C. Weber, Joseph Hwang, Miranda Fischer, Cassandra Moats, Oriene Shiel, Rachele M. Bochart, Hugh Crank, Don Siess, Travis Giobbi, Jeffrey Torgerson, Rebecca Agnor, Lina Gao, Kush Dhody, Jacob P. Lalezari, Ivo Sah Bandar, Alnor M. Carnate, Alina S. Pang, Michael J. Corley, Scott Kelly, Nader Pourhassan, Jeremy Smedley, Benjamin N. Bimber, Scott G. Hansen, Lishomwa C. Ndhlovu, Jonah B. Sacha
Publikováno v:
PLoS pathogens. 18(3)
The CCR5-specific antibody Leronlimab is being investigated as a novel immunotherapy that can suppress HIV replication with minimal side effects. Here we studied the virological and immunological consequences of Leronlimab in chronically CCR5-tropic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::144bb34dc795ff5d767de8ed89e93a35
https://pubmed.ncbi.nlm.nih.gov/35358290
https://pubmed.ncbi.nlm.nih.gov/35358290