Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Whitney C Weber"'
Autor:
Whitney C Weber, Caralyn S Labriola, Craig N Kreklywich, Karina Ray, Nicole N Haese, Takeshi F Andoh, Michael Denton, Samuel Medica, Magdalene M Streblow, Patricia P Smith, Nobuyo Mizuno, Nina Frias, Miranda B Fisher, Aaron M Barber-Axthelm, Kimberly Chun, Samantha Uttke, Danika Whitcomb, Victor DeFilippis, Shauna Rakshe, Suzanne S Fei, Michael K Axthelm, Jeremy V Smedley, Daniel N Streblow
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 11, p e0011742 (2023)
Mayaro virus (MAYV) is a mosquito-transmitted alphavirus that causes debilitating and persistent arthritogenic disease. While MAYV was previously reported to infect non-human primates (NHP), characterization of MAYV pathogenesis is currently lacking.
Externí odkaz:
https://doaj.org/article/9deed2140f2e40a9aabdd1d8e7593a3d
Autor:
John M Powers, Zoe L Lyski, Whitney C Weber, Michael Denton, Magdalene M Streblow, Adam T Mayo, Nicole N Haese, Chad D Nix, Rachel Rodríguez-Santiago, Luisa I Alvarado, Vanessa Rivera-Amill, William B Messer, Daniel N Streblow
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 3, p e0011154 (2023)
Infections with Chikungunya virus, a mosquito-borne alphavirus, cause an acute febrile syndrome often followed by chronic arthritis that persists for months to years post-infection. Neutralizing antibodies are the primary immune correlate of protecti
Externí odkaz:
https://doaj.org/article/894808822a7c4cfb80eeb9c69640586f
Autor:
Dawn K Slifka, Hans-Peter Raué, Whitney C Weber, Takeshi F Andoh, Craig N Kreklywich, Victor R DeFilippis, Daniel N Streblow, Mark K Slifka, Ian J Amanna
Publikováno v:
PLoS Pathogens, Vol 18, Iss 7, p e1010695 (2022)
Chikungunya virus (CHIKV) is an emerging/re-emerging mosquito-borne pathogen responsible for explosive epidemics of febrile illness characterized by debilitating polyarthralgia and the risk of lethal infection among the most severe cases. Despite the
Externí odkaz:
https://doaj.org/article/bd601b20f14f4acd9fe7197a3cc82baf
Autor:
Xiao L Chang, Jason S Reed, Gabriela M Webb, Helen L Wu, Jimmy Le, Katherine B Bateman, Justin M Greene, Cleiton Pessoa, Courtney Waytashek, Whitney C Weber, Joseph Hwang, Miranda Fischer, Cassandra Moats, Oriene Shiel, Rachele M Bochart, Hugh Crank, Don Siess, Travis Giobbi, Jeffrey Torgerson, Rebecca Agnor, Lina Gao, Kush Dhody, Jacob P Lalezari, Ivo Sah Bandar, Alnor M Carnate, Alina S Pang, Michael J Corley, Scott Kelly, Nader Pourhassan, Jeremy Smedley, Benjamin N Bimber, Scott G Hansen, Lishomwa C Ndhlovu, Jonah B Sacha
Publikováno v:
PLoS Pathogens, Vol 18, Iss 3, p e1010396 (2022)
The CCR5-specific antibody Leronlimab is being investigated as a novel immunotherapy that can suppress HIV replication with minimal side effects. Here we studied the virological and immunological consequences of Leronlimab in chronically CCR5-tropic
Externí odkaz:
https://doaj.org/article/e58ad860af654e17bfc075a249a3a48a
Autor:
Gabriela M Webb, Jhomary Molden, Kathleen Busman-Sahay, Shaheed Abdulhaqq, Helen L Wu, Whitney C Weber, Katherine B Bateman, Jason S Reed, Mina Northrup, Nicholas Maier, Shiho Tanaka, Lina Gao, Brianna Davey, Benjamin L Carpenter, Michael K Axthelm, Jeffrey J Stanton, Jeremy Smedley, Justin M Greene, Jeffrey T Safrit, Jacob D Estes, Pamela J Skinner, Jonah B Sacha
Publikováno v:
PLoS Pathogens, Vol 16, Iss 3, p e1008339 (2020)
Despite the success of antiretroviral therapy (ART) to halt viral replication and slow disease progression, this treatment is not curative and there remains an urgent need to develop approaches to clear the latent HIV reservoir. The human IL-15 super
Externí odkaz:
https://doaj.org/article/01a8e5f9eca0493ca269580027d9bf0e
Autor:
Xiao L. Chang, Gabriela M. Webb, Helen L. Wu, Justin M. Greene, Shaheed Abdulhaqq, Katherine B. Bateman, Jason S. Reed, Cleiton Pessoa, Whitney C. Weber, Nicholas Maier, Glen M. Chew, Roxanne M. Gilbride, Lina Gao, Rebecca Agnor, Travis Giobbi, Jeffrey Torgerson, Don Siess, Nicole Burnett, Miranda Fischer, Oriene Shiel, Cassandra Moats, Bruce Patterson, Kush Dhody, Scott Kelly, Nader Pourhassan, Diogo M. Magnani, Jeremy Smedley, Benjamin N. Bimber, Nancy L. Haigwood, Scott G. Hansen, Timothy R. Brown, Lishomwa C. Ndhlovu, Jonah B. Sacha
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
CCR5 is a co-receptor for many transmitted HIV strains. Here, the authors show that biweekly injection of the CCR5-specific antibody Leronlimab protects rhesus macaques against infection following repeated intrarectal challenges of a CCR5-tropic SHIV
Externí odkaz:
https://doaj.org/article/e057d02dc1bf44278b9075dfe29c62e7
Autor:
Helen L. Wu, Kathleen Busman-Sahay, Whitney C. Weber, Courtney M. Waytashek, Carla D. Boyle, Katherine B. Bateman, Jason S. Reed, Joseph M. Hwang, Christine Shriver-Munsch, Tonya Swanson, Mina Northrup, Kimberly Armantrout, Heidi Price, Mitch Robertson-LeVay, Samantha Uttke, Mithra R. Kumar, Emily J. Fray, Sol Taylor-Brill, Stephen Bondoc, Rebecca Agnor, Stephanie L. Junell, Alfred W. Legasse, Cassandra Moats, Rachele M. Bochart, Joseph Sciurba, Benjamin N. Bimber, Michelle N. Sullivan, Brandy Dozier, Rhonda P. MacAllister, Theodore R. Hobbs, Lauren D. Martin, Angela Panoskaltsis-Mortari, Lois M.A. Colgin, Robert F. Siliciano, Janet D. Siliciano, Jacob D. Estes, Jeremy V. Smedley, Michael K. Axthelm, Gabrielle Meyers, Richard T. Maziarz, Benjamin J. Burwitz, Jeffrey J. Stanton, Jonah B. Sacha
Publikováno v:
Immunity.
Autor:
Bruce K. Patterson, Whitney C. Weber, Gabriela M. Webb, Katherine B. Bateman, Cleiton Pessoa, Shaheed A. Abdulhaqq, Lina Gao, Benjamin N. Bimber, Jonah B. Sacha, Scott G. Hansen, Xiao L. Chang, Justin M. Greene, Kush Dhody, Scott Kelly, Nancy L. Haigwood, Rebecca Agnor, Cassandra Moats, Glen M. Chew, Roxanne M. Gilbride, Jeremy Smedley, Nicole D Burnett, Oriene Shiel, Nicholas Maier, Don Siess, Lishomwa C. Ndhlovu, Miranda Fischer, Timothy R. Brown, Diogo M. Magnani, Jason S. Reed, Travis Giobbi, Jeffrey Torgerson, Helen L. Wu, Nader Pourhassan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications
Nature Communications
In the absence of a prophylactic vaccine, the use of antiretroviral therapy (ART) as pre-exposure prophylaxis (PrEP) to prevent HIV acquisition by uninfected individuals is a promising approach to slowing the epidemic, but its efficacy is hampered by
Autor:
Alfred W. Legasse, Mina Northrup, Michael K. Axthelm, Tonya Swanson, Cassandra Moats, Whitney C. Weber, Jeremy Smedley, Kimberly Armantrout, Lauren D. Martin, Christine Shriver-Munsch, Helen L. Wu, Katherine B. Bateman, Justin M. Greene, Richard T. Maziarz, Benjamin J. Burwitz, Theodore R. Hobbs, Jonah B. Sacha, Nicholas Maier
Publikováno v:
J Clin Apher
Macaques are physiologically relevant animal models of human immunology and infectious disease that have provided key insights and advanced clinical treatment in transplantation, vaccinology, and HIV/AIDS. However, the small size of macaques is a stu
Autor:
Dawn K. Slifka, Hans-Peter Raué, Whitney C. Weber, Takeshi F. Andoh, Craig N. Kreklywich, Victor R. DeFilippis, Daniel N. Streblow, Mark K. Slifka, Ian J. Amanna
Publikováno v:
PLoS pathogens. 18(7)
Chikungunya virus (CHIKV) is an emerging/re-emerging mosquito-borne pathogen responsible for explosive epidemics of febrile illness characterized by debilitating polyarthralgia and the risk of lethal infection among the most severe cases. Despite the