Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Whitney Bullard"'
Autor:
Nathan Ungerleider, Whitney Bullard, Mehmet Kara, Xia Wang, Claire Roberts, Rolf Renne, Scott Tibbetts, Erik K Flemington
Publikováno v:
PLoS Pathogens, Vol 17, Iss 5, p e1009217 (2021)
The Epstein Barr virus (EBV) contributes to the tumor phenotype through a limited set of primarily non-coding viral RNAs, including 31 mature miRNAs. Here we investigated the impact of EBV miRNAs on remodeling the tumor cell transcriptome. Strikingly
Externí odkaz:
https://doaj.org/article/125eb20df3264987b2591a0c8ed0096e
Autor:
Ramani N. Chavan, Efrem S. Lim, Jacquelyn Kilbourne, Jordan R. Yaron, Simona Kraberger, Barbara H. Munk, Juan Maldonado, Arvind Varsani, Amanda M. Tafoya, Erling Olaf Koppang, Scott A. Tibbetts, Alison Stern-Harbutte, Rosa Krajmalnik-Brown, Liqiang Zhang, Shahar Keinan, Whitney Bullard, Alexandra Lucas, Sriram Ambadapadi
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Immunopathogenesis in systemic viral infections can induce a septic state with leaky capillary syndrome, disseminated coagulopathy, and high mortality with limited treatment options. Murine gammaherpesvirus-68 (MHV-68) intraperitoneal infection is a
Publikováno v:
mBio, Vol 10, Iss 4, p e00996-19 (2019)
mBio, Vol 10, Iss 4 (2019)
mBio, Vol 10, Iss 4 (2019)
Gammaherpesviruses, including the human pathogens Epstein-Barr virus (EBV) and Kaposi’s sarcoma-associated herpesvirus (KSHV), directly contribute to the genesis of multiple types of malignancies, including B cell lymphomas. In vivo, these viruses
Autor:
Rolf Renne, Whitney Bullard, Claire Roberts, Scott A. Tibbetts, Mehmet Kara, Nathan Ungerleider, Erik K. Flemington, Xia Wang
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 5, p e1009217 (2021)
PLoS Pathogens, Vol 17, Iss 5, p e1009217 (2021)
The Epstein Barr virus (EBV) contributes to the tumor phenotype through a limited set of primarily non-coding viral RNAs, including 31 mature miRNAs. Here we investigated the impact of EBV miRNAs on remodeling the tumor cell transcriptome. Strikingly
Autor:
Donghang Zheng, Mee Y Bartee, Liying Liu, Ian B. Hogue, Alexandra Lucas, Scott A. Tibbetts, Whitney Bullard, Liqiang Zhang, Hao Chen, Jordan R. Yaron
Publikováno v:
Viruses, Vol 10, Iss 10, p 518 (2018)
Viruses
Volume 10
Issue 10
Viruses
Volume 10
Issue 10
Inflammatory bowel disease (IBD) and Clostridium difficile infection cause gastrointestinal (GI) distension and, in severe cases, toxic megacolon with risk of perforation and death. Herpesviruses have been linked to severe GI dilatation. MHV-68 is a
Publikováno v:
Trends in cancer. 4(11)
EBV and KSHV are etiologic agents of multiple types of lymphomas and carcinomas. The frequency of EBV(+) or KSHV(+) malignancies arising in immunocompromised individuals reflects the intricate evolutionary balance established between these viruses an
Publikováno v:
Biology methods and protocols
Recently, 5-hydroxymethyluracil (5hmU) was identified in mammalian genomic DNA as an oxidative product of thymine by the ten-eleven translocation (TET) proteins. While the biological role of this modification remains unclear, identifying its genomic
Publikováno v:
Journal of Biological Chemistry. 289:20273-20282
O-linked glucosylation of thymine in DNA (base J) is an important regulatory epigenetic mark in trypanosomatids. β-d-glucopyranosyloxymethyluracil (base J) synthesis is initiated by the JBP1/2 enzymes that hydroxylate thymine, forming 5-hydroxymethy
Autor:
Whitney Bullard, Jordan R. Yaron, Amanda M. Tafoya, Shahar Keinan, Barbara H. Munk, Sriram Ambadapadi, Jacquelyn Kilbourne, E. Lim, Juan Maldonado, Scott A. Tibbetts, Erling Olaf Koppang, L. M. Zhang, Arvind Varsani, Alexandra Lucas, R. Thomas, R. Chavan
Publikováno v:
Atherosclerosis. 287:e76
Autor:
Stephen L. Hajduk, Whitney Bullard, Paul Capewell, Rudo Kieft, Annette MacLeod, Nicola Veitch
Publikováno v:
Virulence
The haptoglobin-hemoglobin receptor (HpHbR) of African trypanosomes plays a critical role in human innate immunity against these parasites. Localized to the flagellar pocket of the veterinary pathogen Trypanosoma brucei brucei this receptor binds Try