Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Whitney A. Spannuth"'
Autor:
Charles N. Landen, Tae-Jin Kim, Yvonne G. Lin, William M. Merritt, Aparna A. Kamat, Liz Y. Han, Whitney A. Spannuth, Alpa M. Nick, Nicholas B. Jennnings, Michael S. Kinch, David Tice, Anil K. Sood
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 10, Iss 11, Pp 1259-1267 (2008)
The αvβ3 integrin is expressed on proliferating endothelial cells and some cancer cells, but its expression on ovarian cancer cells and its potential as a therapeutic target are unknown. In this study, expression of the αvβ3 integrin on ovarian c
Externí odkaz:
https://doaj.org/article/f1b1524dd8434c41b2694de3d3bf3073
Autor:
Anil K. Sood, Parkash S. Gill, Gabriel Lopez-Berestein, Valery Krasnoperov, Yue Zhou, Pablo E. Vivas-Mejia, Robert L. Coleman, William M. Merritt, Yvonne G. Lin, Nicholas B. Jennings, Ren Liu, Alpa M. Nick, Myrthala Moreno-Smith, Sun-Joo Lee, Mian M.K. Shahzad, Masato Nishimura, Amy R. Carroll, Rebecca L. Stone, Lingegowda S. Mangala, Whitney A. Spannuth
EphB4 is a transmembrane receptor tyrosine kinase that plays an important role in neural plasticity and angiogenesis. EphB4 is overexpressed in ovarian cancer and is predictive of poor clinical outcome. However, the biological significance of EphB4 i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8501cbac8362877b0e4244ba73e2362c
https://doi.org/10.1158/1535-7163.c.6531744
https://doi.org/10.1158/1535-7163.c.6531744
Autor:
Anil K. Sood, Svetlana Lutsenko, Gabriel Lopez-Berestein, Zahid H. Siddik, Robert L. Coleman, Judith K. Wolf, Pablo E. Vivas-Mejia, Nicholas B. Jennings, Jeong-Won Lee, Christopher G. Danes, Alpa M. Nick, Yvonne G. Lin, Mian M.K. Shahzad, Takemi Tanaka, Whitney A. Spannuth, Guillermo N. Armaiz-Pena, Jyotsna B. Halder, Erik S. Leshane, Rosemarie Schmandt, Vesna Zuzel, Lingegowda S. Mangala
Purpose: Resistance to platinum chemotherapy remains a significant problem in ovarian carcinoma. Here, we examined the biological mechanisms and therapeutic potential of targeting a critical platinum resistance gene, ATP7B, using both in vitro and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::574928cbefc6bae28a5acd99194701ef
https://doi.org/10.1158/1078-0432.c.6517644
https://doi.org/10.1158/1078-0432.c.6517644
Autor:
Anil K. Sood, Parkash S. Gill, Gabriel Lopez-Berestein, Valery Krasnoperov, Yue Zhou, Pablo E. Vivas-Mejia, Robert L. Coleman, William M. Merritt, Yvonne G. Lin, Nicholas B. Jennings, Ren Liu, Alpa M. Nick, Myrthala Moreno-Smith, Sun-Joo Lee, Mian M.K. Shahzad, Masato Nishimura, Amy R. Carroll, Rebecca L. Stone, Lingegowda S. Mangala, Whitney A. Spannuth
Supplementary Figure 1 from Converging Evidence for Efficacy from Parallel EphB4-Targeted Approaches in Ovarian Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55d51450314c4e9a5c62f57cd6364469
https://doi.org/10.1158/1535-7163.22485048
https://doi.org/10.1158/1535-7163.22485048
Autor:
Anil K. Sood, William R. Brinkley, Diane C. Bodurka, Robert L. Coleman, Michael J. Gray, Kwong K. Wong, Charles N. Landen, Alpa M. Nick, Whitney A. Spannuth, Liz Y. Han, Aparna A. Kamat, Chunhua Lu, Guillermo N. Armaiz-Pena, Yvonne T.M. Tsang, Mian M.K. Shahzad, Seung Wook Kim, Lingegowda S. Mangala, William M. Merritt, Anand Immaneni, Yvonne G. Lin
Purpose: The Aurora kinase family plays pivotal roles in mitotic integrity and cell cycle. We sought to determine the effects of inhibiting Aurora kinase on ovarian cancer growth in an orthotopic mouse model using a small molecule pan-Aurora kinase i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::787fd937fd2b197674240a86de459219
https://doi.org/10.1158/1078-0432.c.6516907
https://doi.org/10.1158/1078-0432.c.6516907
Autor:
Anil K. Sood, Rakesh Kumar, Robert L. Coleman, Mian M.K. Shahzad, Rebecca L. Stone, Aparna A. Kamat, Whitney A. Spannuth, Yvonne G. Lin, ShuYun Zhang, Nicholas Jennings, Melissa Dumble, Koji Matsuo, Chunhua Lu, Amy R. Carroll, Alpa M. Nick, William M. Merritt
This study aimed to investigate the antitumor and antiangiogenic effects utilizing a novel therapy regimen of metronomic topotecan and pazopanib, a multireceptor tyrosine kinase inhibitor. In vitro (Western blot) and in vivo dose-finding experiments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bf07fcfcff85d92bfa1417d20bc40f9
https://doi.org/10.1158/1535-7163.c.6532178.v1
https://doi.org/10.1158/1535-7163.c.6532178.v1
Autor:
Anil K. Sood, Svetlana Lutsenko, Gabriel Lopez-Berestein, Zahid H. Siddik, Robert L. Coleman, Judith K. Wolf, Pablo E. Vivas-Mejia, Nicholas B. Jennings, Jeong-Won Lee, Christopher G. Danes, Alpa M. Nick, Yvonne G. Lin, Mian M.K. Shahzad, Takemi Tanaka, Whitney A. Spannuth, Guillermo N. Armaiz-Pena, Jyotsna B. Halder, Erik S. Leshane, Rosemarie Schmandt, Vesna Zuzel, Lingegowda S. Mangala
Supplementary Data from Therapeutic Targeting of ATP7B in Ovarian Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24ff0d02e1547a24fb9f7b22bad2beeb
https://doi.org/10.1158/1078-0432.22440294
https://doi.org/10.1158/1078-0432.22440294
Autor:
Anil K. Sood, Rakesh Kumar, Robert L. Coleman, Mian M.K. Shahzad, Rebecca L. Stone, Aparna A. Kamat, Whitney A. Spannuth, Yvonne G. Lin, ShuYun Zhang, Nicholas Jennings, Melissa Dumble, Koji Matsuo, Chunhua Lu, Amy R. Carroll, Alpa M. Nick, William M. Merritt
Supplementary Data from Bridging the Gap between Cytotoxic and Biologic Therapy with Metronomic Topotecan and Pazopanib in Ovarian Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0174b849e8c2d46c0c5319fa3ed40af5
https://doi.org/10.1158/1535-7163.22485995.v1
https://doi.org/10.1158/1535-7163.22485995.v1
Autor:
Anil K. Sood, Kapil Mehta, Gabriel Lopez-Berestein, Robert L. Coleman, Michael T. Deavers, Pablo E. Vivas-Mejia, Derek J. Fiterman, Alpa M. Nick, Whitney A. Spannuth, William M. Merritt, Yvonne G. Lin, Jansina Y. Fok, Lingegowda S. Mangala, Jee Young Hwang
Supplementary Figure 1 from Clinical and Biological Significance of Tissue Transglutaminase in Ovarian Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c71539f6ec5668e1c00a8251d0493a3
https://doi.org/10.1158/0008-5472.22374885
https://doi.org/10.1158/0008-5472.22374885
Autor:
Anil K. Sood, Vikas Kundra, Robert L. Coleman, David M. Gershenson, Robert Langley, Whitney A. Spannuth, Nicholas Jennings, William M. Merritt, Yvonne G. Lin, Chunhua Lu, Liz Y. Han, Aparna A. Kamat, Charles N. Landen, Murali Ravoori, Tae Jin Kim
Supplementary Figure 1 from Antitumor and Antivascular Effects of AVE8062 in Ovarian Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc45c0d253595d990484e26a6e06792d
https://doi.org/10.1158/0008-5472.22367396
https://doi.org/10.1158/0008-5472.22367396