Zobrazeno 1 - 10
of 2 581
pro vyhledávání: '"White matter hyperintensity"'
Publikováno v:
Zhongguo cuzhong zazhi, Vol 19, Iss 8, Pp 931-937 (2024)
目的 探讨不同亚型脑白质高信号(white matter hyperintensity,WMH)及脑白质高信号半暗带(white matter hyperintensity penumbra,WMH-P)内血流灌注、微结构损伤与认知障碍的关系。 方法 前瞻性连续
Externí odkaz:
https://doaj.org/article/f79a82004b8f43dba4b6cd76e3d3abee
Autor:
Aishwarya Pradeep, Sheelakumari Raghavan, Scott A. Przybelski, Gregory M. Preboske, Christopher G. Schwarz, Val J. Lowe, David S. Knopman, Ronald C. Petersen, Clifford R. Jack, Jonathan Graff-Radford, Petrice M. Cogswell, Prashanthi Vemuri
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Background White matter hyperintensities (WMH) are considered hallmark features of cerebral small vessel disease and have recently been linked to Alzheimer’s disease (AD) pathology. Their distinct spatial distributions, namely periventricu
Externí odkaz:
https://doaj.org/article/e98a5ea8c19f4da7a4b877bae77a1e08
Autor:
Masashi Kuwabara, Fusao Ikawa, Shinji Nakazawa, Saori Koshino, Daizo Ishii, Hiroshi Kondo, Takeshi Hara, Yuyo Maeda, Ryo Sato, Taiki Kaneko, Shiyuki Maeyama, Yuki Shimahara, Nobutaka Horie
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract We aimed to develop a new artificial intelligence software that can automatically extract and measure the volume of white matter hyperintensities (WMHs) in head magnetic resonance imaging (MRI) using only thick-slice fluid-attenuated inversi
Externí odkaz:
https://doaj.org/article/06bd9e17a7434a2f9326c8c39e414b5c
Autor:
Rongxiang Tang, Erik Buchholz, Anders M. Dale, Robert A. Rissman, Christine Fennema-Notestine, Nathan A. Gillespie, Donald J Hagler, Michael J. Lyons, Michael C. Neale, Matthew S. Panizzon, Olivia K. Puckett, Chandra A. Reynolds, Carol E. Franz, William S. Kremen, Jeremy A. Elman
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-11 (2024)
Abstract Background Plasma neurofilament light chain (NfL) is a promising biomarker of neurodegeneration with potential clinical utility in monitoring the progression of neurodegenerative diseases. However, the cross-sectional associations of plasma
Externí odkaz:
https://doaj.org/article/76973dd443624b90a1ebf2477b1724ec
Autor:
Hyun Song, Pradyumna K. Bharadwaj, David A. Raichlen, Christian G. Habeck, Matthew D. Grilli, Matthew J. Huentelman, Georg A. Hishaw, Theodore P. Trouard, Gene E. Alexander
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
Homocysteine (Hcy) is a cardiovascular risk factor implicated in cognitive impairment and cerebrovascular disease but has also been associated with Alzheimer’s disease. In 160 healthy older adults (mean age = 69.66 ± 9.95 years), we sought to inve
Externí odkaz:
https://doaj.org/article/f5320eed5a0245309c690ea3f60b1ff3
Autor:
Ying Zhou, Rui Xue, Yifei Li, Wang Ran, Yuping Chen, Zhongyu Luo, Kemeng Zhang, Ruoxia Zhang, Junjun Wang, Mengmeng Fang, Cong Chen, Min Lou
Publikováno v:
Advanced Science, Vol 11, Iss 26, Pp n/a-n/a (2024)
Abstract White matter hyperintensity (WMH) represents a critical global medical concern linked to cognitive decline and dementia, yet its underlying mechanisms remain poorly understood. Here, humans are directly demonstrated that high WMH burden corr
Externí odkaz:
https://doaj.org/article/b985d4b0aa984363b283f29564a54b0f
Autor:
Woo-Jin Cha, Dahyun Yi, Hyejin Ahn, Min Soo Byun, Yoon Young Chang, Jung-Min Choi, Kyungtae Kim, Hyeji Choi, Gijung Jung, Koung Mi Kang, Chul-Ho Sohn, Yun-Sang Lee, Yu Kyeong Kim, Dong Young Lee
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-9 (2024)
Abstract Background Growing evidence suggests that not only cerebrovascular disease but also Alzheimer’s disease (AD) pathological process itself cause cerebral white matter degeneration, resulting in white matter hyperintensities (WMHs). Some prec
Externí odkaz:
https://doaj.org/article/b77a8402b6f2467792715e93d6937e7b
Autor:
Binghan Li, Zhengsheng Gu, Weisen Wang, Bingying Du, Chenghao Wu, Bin Li, Tianren Wang, Ge Yin, Xin Gao, Jingjing Chen, Xiaoying Bi, Hailing Zhang, Xu Sun
Publikováno v:
BMC Neurology, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background The global prevalence of VCI has increased steadily in recent years, but diagnostic biomarkers for VCI in patients with non-disabling ischemic cerebrovascular incidents (NICE) remain indefinite. The primary objective of this resea
Externí odkaz:
https://doaj.org/article/0fb865a4cf1b4ea7b2f8fdd9081d3aec
Autor:
Rayan Anbar, Siana Jones, Nish Chaturvedi, Carole Sudre, Marcus Richards, Salahaden R. Sultan, Alun D. Hughes
Publikováno v:
Atherosclerosis Plus, Vol 55, Iss , Pp 39-46 (2024)
Background: Cognitive function has an important role in determining the quality of life of older adults. Cardiovascular disease (CVD) is common in older people and may compromise cognitive performance; however, the extent to which this is related to
Externí odkaz:
https://doaj.org/article/7578fadabd074f959903c85c39333b58
Publikováno v:
BMC Neurology, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Objective This study aimed to investigate the association between white matter hyperintensity (WMH) burden and pial collaterals in acute strokes caused by intracranial large artery occlusion treated with mechanical thrombectomy in the anteri
Externí odkaz:
https://doaj.org/article/25453594899645ba892463aec9b81f8d