Zobrazeno 1 - 2
of 2
pro vyhledávání: '"White People/genetics"'
Autor:
Yi Ding, Kangcheng Hou, Ziqi Xu, Aditya Pimplaskar, Ella Petter, Kristin Boulier, Florian Privé, Bjarni J. Vilhjálmsson, Loes M. Olde Loohuis, Bogdan Pasaniuc
Publikováno v:
Nature, vol 618, iss 7966
Ding, Y, Hou, K, Xu, Z, Pimplaskar, A, Petter, E, Boulier, K, Privé, F, Vilhjálmsson, B J, Olde Loohuis, L M & Pasaniuc, B 2023, ' Polygenic scoring accuracy varies across the genetic ancestry continuum ', Nature, vol. 618, pp. 774-781 . https://doi.org/10.1038/s41586-023-06079-4
Ding, Y, Hou, K, Xu, Z, Pimplaskar, A, Petter, E, Boulier, K, Privé, F, Vilhjálmsson, B J, Olde Loohuis, L M & Pasaniuc, B 2023, ' Polygenic scoring accuracy varies across the genetic ancestry continuum ', Nature, vol. 618, pp. 774-781 . https://doi.org/10.1038/s41586-023-06079-4
Polygenic scores (PGSs) have limited portability across different groupings of individuals (for example, by genetic ancestries and/or social determinants of health), preventing their equitable use1–3. PGS portability has typically been assessed usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::228435a6191fd5baceca508fb65d8edf
https://escholarship.org/uc/item/4m17p3jq
https://escholarship.org/uc/item/4m17p3jq
Autor:
Gerome Breen, Suzanne Sniekers, Neil Pendleton, Robert Plomin, Antony Payton, Magnus Johannesson, Anke R. Hammerschlag, Sven Stringer, Philipp Koellinger, Matt McGue, David Cesarini, Najaf Amin, Christopher F. Chabris, Delilah Zabaneh, Cornelia M. van Duijn, Cornelius A. Rietveld, Aysu Okbay, Jonathan R. I. Coleman, Michael B. Miller, Danielle Posthuma, Eva Krapohl, Erdogan Taskesen, William G. Iacono, Kyoko Watanabe, Philip R. Jansen, Patrik K. E. Magnusson, William E R Ollier, James J. Lee, Henning Tiemeier, M. Arfan Ikram
Publikováno v:
Nature Genetics, 49(7), 1107-1112. Nature Publishing Group
Sniekers, S, Stringer, S, Watanabe, K, Jansen, P R, Coleman, J R I, Krapohl, E, Taskesen, E, Hammerschlag, A R, Okbay, A, Zabaneh, D, Amin, N, Breen, G, Cesarini, D, Chabris, C F, Iacono, W G, Ikram, M A, Johannesson, M, Koellinger, P, Lee, J J, Magnusson, P K E, McGue, M, Miller, M B, Ollier, W E R, Payton, A, Pendleton, N, Plomin, R, Rietveld, C A, Tiemeier, H, Van Duijn, C M & Posthuma, D 2017, ' Genome-wide association meta-A nalysis of 78,308 individuals identifies new loci and genes influencing human intelligence ', Nature Genetics, vol. 49, no. 7, pp. 1107-1112 . https://doi.org/10.1038/ng.3869
Nature Genetics
Sniekers, S, Stringer, S, Watanabe, K, Jansen, P R, Coleman, J R I, Krapohl, E, Taskesen, E, Hammerschlag, A R, Okbay, A, Zabaneh, D, Amin, N, Breen, G, Cesarini, D, Chabris, C F, Iacono, W G, Ikram, M A, Johannesson, M, Koellinger, P, Lee, J J, Magnusson, P K E, McGue, M, Miller, M B, Ollier, W E R, Payton, A, Pendleton, N, Plomin, R, Rietveld, C A, Tiemeier, H, van Duijn, C M & Posthuma, D 2017, ' Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence ', Nature Genetics, vol. 49, no. 7, pp. 1107-1112 . https://doi.org/10.1038/ng.3869
Nature genetics
Nature genetics, 49(7), 1107-1112. Nature Publishing Group
Sniekers, S, Stringer, S, Watanabe, K, Jansen, P R, Coleman, J, Krapohl, E, Taskesen, E, Hammerschlag, A R, Okbay, A, Zabaneh, D, Amin, N, Breen, G, Cesarini, D, Chabris, C F, Iacono, W G, Ikram, M A, Johannesson, M, Koellinger, P, Lee, J J, Magnusson, P K E, McGue, M, Miller, M B, Ollier, W E R, Payton, A, Pendleton, N, Plomin, R, Rietveld, C A, Tiemeier, H, van Duijn, C M & Posthuma, D 2017, ' Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence ', Nature Genetics, vol. 49, no. 7, pp. 1107–1112 . https://doi.org/10.1038/ng.3869
Sniekers, S, Stringer, S, Watanabe, K, Jansen, P R, Coleman, J R I, Krapohl, E, Taskesen, E, Hammerschlag, A R, Okbay, A, Zabaneh, D, Amin, N, Breen, G, Cesarini, D, Chabris, C F, Iacono, W G, Ikram, M A, Johannesson, M, Koellinger, P, Lee, J J, Magnusson, P K E, McGue, M, Miller, M B, Ollier, W E R, Payton, A, Pendleton, N, Plomin, R, Rietveld, C A, Tiemeier, H, Van Duijn, C M & Posthuma, D 2017, ' Genome-wide association meta-A nalysis of 78,308 individuals identifies new loci and genes influencing human intelligence ', Nature Genetics, vol. 49, no. 7, pp. 1107-1112 . https://doi.org/10.1038/ng.3869
Nature Genetics
Sniekers, S, Stringer, S, Watanabe, K, Jansen, P R, Coleman, J R I, Krapohl, E, Taskesen, E, Hammerschlag, A R, Okbay, A, Zabaneh, D, Amin, N, Breen, G, Cesarini, D, Chabris, C F, Iacono, W G, Ikram, M A, Johannesson, M, Koellinger, P, Lee, J J, Magnusson, P K E, McGue, M, Miller, M B, Ollier, W E R, Payton, A, Pendleton, N, Plomin, R, Rietveld, C A, Tiemeier, H, van Duijn, C M & Posthuma, D 2017, ' Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence ', Nature Genetics, vol. 49, no. 7, pp. 1107-1112 . https://doi.org/10.1038/ng.3869
Nature genetics
Nature genetics, 49(7), 1107-1112. Nature Publishing Group
Sniekers, S, Stringer, S, Watanabe, K, Jansen, P R, Coleman, J, Krapohl, E, Taskesen, E, Hammerschlag, A R, Okbay, A, Zabaneh, D, Amin, N, Breen, G, Cesarini, D, Chabris, C F, Iacono, W G, Ikram, M A, Johannesson, M, Koellinger, P, Lee, J J, Magnusson, P K E, McGue, M, Miller, M B, Ollier, W E R, Payton, A, Pendleton, N, Plomin, R, Rietveld, C A, Tiemeier, H, van Duijn, C M & Posthuma, D 2017, ' Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence ', Nature Genetics, vol. 49, no. 7, pp. 1107–1112 . https://doi.org/10.1038/ng.3869
Intelligence is associated with important economic and health-related life outcomes. Despite intelligence having substantial heritability (0.54) and a confirmed polygenic nature, initial genetic studies were mostly underpowered. Here we report a meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::547e1e3e477a5461cb76752c5e210a0e
http://www.scopus.com/inward/record.url?scp=85020899420&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85020899420&partnerID=8YFLogxK
